Basic Information
Gene ID 2114 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name ETS2
Full Name Protein C-ets-2
Organism Homo sapiens [9606]

Cross Reference
UniProt P15036 UniGene Hs.644231
PDB 4MHV OMIM 164740
KEGG hsa:2114 UCSC uc002yxf.3

Protein Interactions
DIP NULL
IntAct P15036
MINT MINT-132932
STRING 9606.ENSP00000353344

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000353344 Gene3D G3DSA:1.10.10.10 IPR011991 346 466 1.70e-52 Winged helix-turn-helix DNA-binding domain
ENSP00000353344 Gene3D G3DSA:1.10.150.50 IPR013761 81 170 6.20e-35 Sterile alpha motif/pointed domain
ENSP00000353344 Pfam PF00178 IPR000418 363 444 8.10e-40 Ets domain
ENSP00000353344 Pfam PF02198 IPR003118 88 169 9.80e-33 Pointed domain
ENSP00000353344 PIRSF PIRSF001698 IPR016311 1 469 0.00e-00 Transforming protein C-ets
ENSP00000353344 PIRSF PIRSF501032 IPR027276 1 469 0.00e-00 Transforming protein C-ets-2
ENSP00000353344 PRINTS PR00454 IPR000418 363 376 4.90e-31 Ets domain
ENSP00000353344 PRINTS PR00454 IPR000418 387 405 4.90e-31 Ets domain
ENSP00000353344 PRINTS PR00454 IPR000418 406 424 4.90e-31 Ets domain
ENSP00000353344 PRINTS PR00454 IPR000418 425 443 4.90e-31 Ets domain
ENSP00000353344 ProSitePatterns PS00345 IPR000418 365 373 - Ets domain
ENSP00000353344 ProSitePatterns PS00346 IPR000418 409 424 - Ets domain
ENSP00000353344 ProSiteProfiles PS50061 IPR000418 363 443 0.00e-00 Ets domain
ENSP00000353344 ProSiteProfiles PS51433 IPR003118 85 170 0.00e-00 Pointed domain
ENSP00000353344 SMART SM00251 IPR003118 87 170 2.50e-45 Pointed domain
ENSP00000353344 SMART SM00413 IPR000418 362 447 2.80e-59 Ets domain
ENSP00000353344 SUPERFAMILY SSF47769 IPR013761 66 167 0.00e-00 Sterile alpha motif/pointed domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000353344 PF00178 7.69999e-40 Ets Ets-domain
ENSP00000353344 PF02198 5.1e-33 SAM_PNT Sterile alpha motif (SAM)/Pointed domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000353344 GO:0006351 biological_process transcription, DNA-templated
ENSP00000353344 GO:0005634 cellular_component nucleus
ENSP00000353344 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSP00000353344 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9597 Pan paniscus 100968746 9646 Ailuropoda melanoleuca 100477357
9103 Meleagris gallopavo 100545715 9785 Loxodonta africana 100668106
10029 Cricetulus griseus 100774407 9555 Papio anubis 100999646
39432 Saimiri boliviensis 101045985 9669 Mustela putorius furo 101689334
43179 Ictidomys tridecemlineatus 101975209 7897 Latimeria chalumnae 102351338
59463 Myotis lucifugus 102418187 13735 Pelodiscus sinensis 102451780
7955 Danio rerio 326672 9913 Bos taurus ENSBTAG00000009214
9615 Canis familiaris ENSCAFG00000009978 9358 Choloepus hoffmanni ENSCHOG00000008991
9483 Callithrix jacchus ENSCJAG00000005378 10141 Cavia porcellus ENSCPOG00000015014
9361 Dasypus novemcinctus ENSDNOG00000011451 10020 Dipodomys ordii ENSDORG00000006046
9796 Equus caballus ENSECAG00000021269 9365 Erinaceus europaeus ENSEEUG00000015949
9371 Echinops telfairi ENSETEG00000016807 9685 Felis catus ENSFCAG00000007489
9595 Gorilla gorilla ENSGGOG00000015464 8049 Gadus morhua ENSGMOG00000005232
30608 Microcebus murinus ENSMICG00000003203 9544 Macaca mulatta ENSMMUG00000017882
13616 Monodelphis domestica ENSMODG00000020979 61853 Nomascus leucogenys ENSNLEG00000004804
9986 Oryctolagus cuniculus ENSOCUG00000005861 9978 Ochotona princeps ENSOPRG00000002895
9813 Procavia capensis ENSPCAG00000001036 9601 Pongo abelii ENSPPYG00000011421
9598 Pan troglodytes ENSPTRG00000013908 132908 Pteropus vampyrus ENSPVAG00000012135
9305 Sarcophilus harrisii ENSSHAG00000007055 9823 Sus scrofa ENSSSCG00000012068
37347 Tupaia belangeri ENSTBEG00000017397 9478 Tarsius syrichta ENSTSYG00000011695
9739 Tursiops truncatus ENSTTRG00000000796 30538 Vicugna pacos ENSVPAG00000002062
8364 Xenopus tropicalis ENSXETG00000023724 10116 Rattus norvegicus 304063