Basic Information
Gene ID 2186 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name BPTF; FAC1, FALZ
Full Name Nucleosome-remodeling factor subunit BPTF
Organism Homo sapiens [9606]

Cross Reference
UniProt Q12830 UniGene Hs.444200
PDB 3UV2 OMIM 601819
KEGG hsa:2186 UCSC uc002jgf.3

Protein Interactions
DIP DIP-38919N
IntAct Q12830
MINT MINT-3973225
STRING 9606.ENSP00000307208

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000315454 Gene3D G3DSA:1.20.920.10 IPR001487 2803 2822 2.80e-42 Bromodomain
ENSP00000315454 Gene3D G3DSA:1.20.920.10 IPR001487 2932 3033 2.80e-42 Bromodomain
ENSP00000315454 Gene3D G3DSA:3.30.40.10 IPR013083 2862 2918 3.80e-21 Zinc finger, RING/FYVE/PHD-type
ENSP00000315454 Gene3D G3DSA:3.30.40.10 IPR013083 387 445 7.00e-16 Zinc finger, RING/FYVE/PHD-type
ENSP00000315454 PANTHER PTHR22880:SF91 IPR028865 75 3044 0.00e-00 Nucleosome-remodeling factor subunit BPTF, chordates
ENSP00000315454 Pfam PF00439 IPR001487 2937 3018 3.10e-25 Bromodomain
ENSP00000315454 Pfam PF00628 IPR019787 2869 2917 1.10e-09 Zinc finger, PHD-finger
ENSP00000315454 Pfam PF00628 IPR019787 393 435 6.60e-08 Zinc finger, PHD-finger
ENSP00000315454 Pfam PF02791 IPR004022 241 300 2.80e-21 DDT domain
ENSP00000315454 PRINTS PR00503 IPR001487 2947 2960 1.70e-17 Bromodomain
ENSP00000315454 PRINTS PR00503 IPR001487 2961 2977 1.70e-17 Bromodomain
ENSP00000315454 PRINTS PR00503 IPR001487 2977 2995 1.70e-17 Bromodomain
ENSP00000315454 PRINTS PR00503 IPR001487 2995 3014 1.70e-17 Bromodomain
ENSP00000315454 ProSitePatterns PS00633 IPR018359 2949 3006 - Bromodomain, conserved site
ENSP00000315454 ProSitePatterns PS01359 IPR019786 2870 2915 - Zinc finger, PHD-type, conserved site
ENSP00000315454 ProSitePatterns PS01359 IPR019786 393 434 - Zinc finger, PHD-type, conserved site
ENSP00000315454 ProSiteProfiles PS50014 IPR001487 2944 3014 0.00e-00 Bromodomain
ENSP00000315454 ProSiteProfiles PS50016 IPR019787 2867 2918 0.00e-00 Zinc finger, PHD-finger
ENSP00000315454 ProSiteProfiles PS50016 IPR019787 390 437 0.00e-00 Zinc finger, PHD-finger
ENSP00000315454 ProSiteProfiles PS50827 IPR018501 240 300 0.00e-00 DDT domain superfamily
ENSP00000315454 SMART SM00249 IPR001965 2869 2916 2.10e-11 Zinc finger, PHD-type
ENSP00000315454 SMART SM00249 IPR001965 392 435 1.10e-13 Zinc finger, PHD-type
ENSP00000315454 SMART SM00297 IPR001487 2925 3033 6.30e-39 Bromodomain
ENSP00000315454 SMART SM00571 IPR018500 240 300 5.50e-29 DDT domain, subgroup
ENSP00000315454 SUPERFAMILY SSF47370 IPR001487 2927 3031 0.00e-00 Bromodomain
ENSP00000315454 SUPERFAMILY SSF57903 IPR011011 2859 2918 0.00e-00 Zinc finger, FYVE/PHD-type
ENSP00000315454 SUPERFAMILY SSF57903 IPR011011 387 443 0.00e-00 Zinc finger, FYVE/PHD-type

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000315454 PF00439 1.1e-25 Bromodomain Bromodomain
ENSP00000315454 PF02791 1.4e-21 DDT DDT domain
ENSP00000315454 PF00628 4e-18 PHD PHD-finger
ENSP00000315454 PF15612 2.5e-05 WHIM1 WSTF, HB1, Itc1p, MBD9 motif 1

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100121474 7070 Tribolium castaneum 100141790
7029 Acyrthosiphon pisum 100165264 30195 Bombus terrestris 100646137
132113 Bombus impatiens 100744854 10029 Cricetulus griseus 100772838
7463 Apis florea 100871253 143995 Megachile rotundata 100880459
34638 Metaseiulus occidentalis 100900860 9597 Pan paniscus 100969364
9555 Papio anubis 101020184 39432 Saimiri boliviensis 101047770
6087 Hydra magnipapillata 101236749 9361 Dasypus novemcinctus ENSDNOG00000001518
9365 Erinaceus europaeus ENSEEUG00000012433 9371 Echinops telfairi ENSETEG00000012826
9785 Loxodonta africana ENSLAFG00000017552 7757 Petromyzon marinus ENSPMAG00000009229
42254 Sorex araneus ENSSARG00000002933 7227 Drosophila melanogaster 44811
7668 Strongylocentrotus purpuratus 575060 9646 Ailuropoda melanoleuca ENSAMEG00000018402
9913 Bos taurus ENSBTAG00000014598 9615 Canis familiaris ENSCAFG00000011552
9358 Choloepus hoffmanni ENSCHOG00000011361 7719 Ciona intestinalis ENSCING00000022802
9483 Callithrix jacchus ENSCJAG00000031506 51511 Ciona savignyi ENSCSAVG00000011536
7955 Danio rerio ENSDARG00000077361 9796 Equus caballus ENSECAG00000019916
9685 Felis catus ENSFCAG00000001929 69293 Gasterosteus aculeatus ENSGACG00000018507
9031 Gallus gallus ENSGALG00000003627 8049 Gadus morhua ENSGMOG00000017629
7897 Latimeria chalumnae ENSLACG00000013815 9315 Macropus eugenii ENSMEUG00000010285
9103 Meleagris gallopavo ENSMGAG00000007560 30608 Microcebus murinus ENSMICG00000012004
59463 Myotis lucifugus ENSMLUG00000002285 9544 Macaca mulatta ENSMMUG00000009734
13616 Monodelphis domestica ENSMODG00000003866 9669 Mustela putorius furo ENSMPUG00000014688
61853 Nomascus leucogenys ENSNLEG00000001556 9258 Ornithorhynchus anatinus ENSOANG00000008050
9986 Oryctolagus cuniculus ENSOCUG00000015866 30611 Otolemur garnettii ENSOGAG00000007027
8128 Oreochromis niloticus ENSONIG00000006459 9978 Ochotona princeps ENSOPRG00000000527
8090 Oryzias latipes ENSORLG00000015227 9601 Pongo abelii ENSPPYG00000008568
13735 Pelodiscus sinensis ENSPSIG00000008454 9598 Pan troglodytes ENSPTRG00000009568
132908 Pteropus vampyrus ENSPVAG00000009712 9305 Sarcophilus harrisii ENSSHAG00000009658
37347 Tupaia belangeri ENSTBEG00000015933 59729 Taeniopygia guttata ENSTGUG00000004512
99883 Tetraodon nigroviridis ENSTNIG00000014125 31033 Takifugu rubripes ENSTRUG00000001955
9478 Tarsius syrichta ENSTSYG00000006308 9739 Tursiops truncatus ENSTTRG00000013967
8364 Xenopus tropicalis ENSXETG00000001592 8083 Xiphophorus maculatus ENSXMAG00000013629