Basic Information | |||
Gene ID | 21869 ; Check Expression Profles ; Check TFs & Targets Binding | ||
Gene Name | Nkx2-1; Nkx-2.1, Titf1, Ttf1 | ||
Full Name | Homeobox protein Nkx-2.1 | ||
Organism | Mus musculus [10090] |
Cross Reference | |||
UniProt | P50220 | UniGene | Mm.89972 |
PDB | NULL | OMIM | NULL |
KEGG | mmu:21869 | UCSC | uc007npf.3 |
Protein Interactions | |
DIP | NULL |
IntAct | NULL |
MINT | NULL |
STRING | 10090.ENSMUSP00000001536 |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
ENSEMBL | |||
REFSEQ | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSMUSP00000001536 | Gene3D | G3DSA:1.10.10.60 | IPR009057 | 149 | 222 | 4.90e-26 | Homeodomain-like |
ENSMUSP00000001536 | Pfam | PF00046 | IPR001356 | 162 | 218 | 1.00e-20 | Homeobox domain |
ENSMUSP00000001536 | PRINTS | PR00024 | IPR020479 | 183 | 194 | 2.60e-05 | Homeodomain, metazoa |
ENSMUSP00000001536 | PRINTS | PR00024 | IPR020479 | 198 | 208 | 2.60e-05 | Homeodomain, metazoa |
ENSMUSP00000001536 | PRINTS | PR00024 | IPR020479 | 208 | 217 | 2.60e-05 | Homeodomain, metazoa |
ENSMUSP00000001536 | ProSitePatterns | PS00027 | IPR017970 | 194 | 217 | - | Homeobox, conserved site |
ENSMUSP00000001536 | ProSiteProfiles | PS50071 | IPR001356 | 159 | 219 | 0.00e-00 | Homeobox domain |
ENSMUSP00000001536 | SMART | SM00389 | IPR001356 | 161 | 223 | 3.60e-27 | Homeobox domain |
ENSMUSP00000001536 | SUPERFAMILY | SSF46689 | IPR009057 | 139 | 221 | 0.00e-00 | Homeodomain-like |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSMUSP00000001536 | PF00046 | 5.8e-21 | Homeobox | Homeobox domain |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
ENSMUSP00000001536 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
ENSMUSP00000001536 | GO:0043565 | molecular_function | sequence-specific DNA binding |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
9796 | Equus caballus | 100146136 | 9823 | Sus scrofa | 100154384 |
7029 | Acyrthosiphon pisum | 100159676 | 10224 | Saccoglossus kowalevskii | 100303502 |
30195 | Bombus terrestris | 100642447 | 132113 | Bombus impatiens | 100749050 |
30611 | Otolemur garnettii | 100945785 | 9597 | Pan paniscus | 100969731 |
39432 | Saimiri boliviensis | 101045016 | 8083 | Xiphophorus maculatus | 102230451 |
6239 | Caenorhabditis elegans | 179877 | 8364 | Xenopus tropicalis | 100135015 |
9555 | Papio anubis | 101000504 | 9669 | Mustela putorius furo | 101689780 |
7897 | Latimeria chalumnae | 102346775 | 13735 | Pelodiscus sinensis | 102460094 |
7227 | Drosophila melanogaster | 3355151 | 9598 | Pan troglodytes | 452867 |
28377 | Anolis carolinensis | ENSACAG00000001528 | 10141 | Cavia porcellus | ENSCPOG00000021321 |
9685 | Felis catus | ENSFCAG00000010502 | 9595 | Gorilla gorilla | ENSGGOG00000026494 |
9785 | Loxodonta africana | ENSLAFG00000028846 | 9978 | Ochotona princeps | ENSOPRG00000003269 |
132908 | Pteropus vampyrus | ENSPVAG00000008167 | 59729 | Taeniopygia guttata | ENSTGUG00000012009 |
7668 | Strongylocentrotus purpuratus | 373506 | 7070 | Tribolium castaneum | 662616 |
9544 | Macaca mulatta | 696771 | 9646 | Ailuropoda melanoleuca | ENSAMEG00000002893 |
7719 | Ciona intestinalis | ENSCING00000006231 | 9483 | Callithrix jacchus | ENSCJAG00000006994 |
51511 | Ciona savignyi | ENSCSAVG00000005749 | 7955 | Danio rerio | ENSDARG00000019835 |
69293 | Gasterosteus aculeatus | ENSGACG00000011301 | 9031 | Gallus gallus | ENSGALG00000020423 |
8049 | Gadus morhua | ENSGMOG00000009141 | 9315 | Macropus eugenii | ENSMEUG00000011797 |
30608 | Microcebus murinus | ENSMICG00000010129 | 59463 | Myotis lucifugus | ENSMLUG00000011377 |
13616 | Monodelphis domestica | ENSMODG00000012691 | 61853 | Nomascus leucogenys | ENSNLEG00000003932 |
8090 | Oryzias latipes | ENSORLG00000008626 | 9305 | Sarcophilus harrisii | ENSSHAG00000009469 |
43179 | Ictidomys tridecemlineatus | ENSSTOG00000023264 | 31033 | Takifugu rubripes | ENSTRUG00000011900 |
9739 | Tursiops truncatus | ENSTTRG00000009491 |