Basic Information
Gene ID 21869 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Nkx2-1; Nkx-2.1, Titf1, Ttf1
Full Name Homeobox protein Nkx-2.1
Organism Mus musculus [10090]

Cross Reference
UniProt P50220 UniGene Mm.89972
PDB NULL OMIM NULL
KEGG mmu:21869 UCSC uc007npf.3

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 10090.ENSMUSP00000001536

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMUSP00000001536 Gene3D G3DSA:1.10.10.60 IPR009057 149 222 4.90e-26 Homeodomain-like
ENSMUSP00000001536 Pfam PF00046 IPR001356 162 218 1.00e-20 Homeobox domain
ENSMUSP00000001536 PRINTS PR00024 IPR020479 183 194 2.60e-05 Homeodomain, metazoa
ENSMUSP00000001536 PRINTS PR00024 IPR020479 198 208 2.60e-05 Homeodomain, metazoa
ENSMUSP00000001536 PRINTS PR00024 IPR020479 208 217 2.60e-05 Homeodomain, metazoa
ENSMUSP00000001536 ProSitePatterns PS00027 IPR017970 194 217 - Homeobox, conserved site
ENSMUSP00000001536 ProSiteProfiles PS50071 IPR001356 159 219 0.00e-00 Homeobox domain
ENSMUSP00000001536 SMART SM00389 IPR001356 161 223 3.60e-27 Homeobox domain
ENSMUSP00000001536 SUPERFAMILY SSF46689 IPR009057 139 221 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMUSP00000001536 PF00046 5.8e-21 Homeobox Homeobox domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMUSP00000001536 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSMUSP00000001536 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9796 Equus caballus 100146136 9823 Sus scrofa 100154384
7029 Acyrthosiphon pisum 100159676 10224 Saccoglossus kowalevskii 100303502
30195 Bombus terrestris 100642447 132113 Bombus impatiens 100749050
30611 Otolemur garnettii 100945785 9597 Pan paniscus 100969731
39432 Saimiri boliviensis 101045016 8083 Xiphophorus maculatus 102230451
6239 Caenorhabditis elegans 179877 8364 Xenopus tropicalis 100135015
9555 Papio anubis 101000504 9669 Mustela putorius furo 101689780
7897 Latimeria chalumnae 102346775 13735 Pelodiscus sinensis 102460094
7227 Drosophila melanogaster 3355151 9598 Pan troglodytes 452867
28377 Anolis carolinensis ENSACAG00000001528 10141 Cavia porcellus ENSCPOG00000021321
9685 Felis catus ENSFCAG00000010502 9595 Gorilla gorilla ENSGGOG00000026494
9785 Loxodonta africana ENSLAFG00000028846 9978 Ochotona princeps ENSOPRG00000003269
132908 Pteropus vampyrus ENSPVAG00000008167 59729 Taeniopygia guttata ENSTGUG00000012009
7668 Strongylocentrotus purpuratus 373506 7070 Tribolium castaneum 662616
9544 Macaca mulatta 696771 9646 Ailuropoda melanoleuca ENSAMEG00000002893
7719 Ciona intestinalis ENSCING00000006231 9483 Callithrix jacchus ENSCJAG00000006994
51511 Ciona savignyi ENSCSAVG00000005749 7955 Danio rerio ENSDARG00000019835
69293 Gasterosteus aculeatus ENSGACG00000011301 9031 Gallus gallus ENSGALG00000020423
8049 Gadus morhua ENSGMOG00000009141 9315 Macropus eugenii ENSMEUG00000011797
30608 Microcebus murinus ENSMICG00000010129 59463 Myotis lucifugus ENSMLUG00000011377
13616 Monodelphis domestica ENSMODG00000012691 61853 Nomascus leucogenys ENSNLEG00000003932
8090 Oryzias latipes ENSORLG00000008626 9305 Sarcophilus harrisii ENSSHAG00000009469
43179 Ictidomys tridecemlineatus ENSSTOG00000023264 31033 Takifugu rubripes ENSTRUG00000011900
9739 Tursiops truncatus ENSTTRG00000009491