Basic Information
Gene ID 228731 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Nkx2-4; Nkx2d
Full Name Homeobox protein Nkx-2.4
Organism Mus musculus [10090]

Cross Reference
UniProt Q9EQM3 UniGene Mm.315498
PDB NULL OMIM NULL
KEGG mmu:228731 UCSC uc008mss.1

Protein Interactions
DIP NULL
IntAct Q9EQM3
MINT MINT-4103884
STRING 10090.ENSMUSP00000066690

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMUSP00000066690 Gene3D G3DSA:1.10.10.60 IPR009057 182 249 5.10e-26 Homeodomain-like
ENSMUSP00000066690 Pfam PF00046 IPR001356 189 245 9.20e-21 Homeobox domain
ENSMUSP00000066690 PRINTS PR00024 IPR020479 210 221 2.30e-05 Homeodomain, metazoa
ENSMUSP00000066690 PRINTS PR00024 IPR020479 225 235 2.30e-05 Homeodomain, metazoa
ENSMUSP00000066690 PRINTS PR00024 IPR020479 235 244 2.30e-05 Homeodomain, metazoa
ENSMUSP00000066690 ProSitePatterns PS00027 IPR017970 221 244 - Homeobox, conserved site
ENSMUSP00000066690 ProSiteProfiles PS50071 IPR001356 186 246 0.00e-00 Homeobox domain
ENSMUSP00000066690 SMART SM00389 IPR001356 188 250 3.60e-27 Homeobox domain
ENSMUSP00000066690 SUPERFAMILY SSF46689 IPR009057 181 248 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMUSP00000066690 PF00046 6.1e-21 Homeobox Homeobox domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMUSP00000066690 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSMUSP00000066690 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100117472 8364 Xenopus tropicalis 100495653
400682 Amphimedon queenslandica 100631730 10029 Cricetulus griseus 100774339
7463 Apis florea 100863232 143995 Megachile rotundata 100878295
30611 Otolemur garnettii 100949924 8083 Xiphophorus maculatus 102226902
34638 Metaseiulus occidentalis 100906762 9555 Papio anubis 101009227
7460 Apis mellifera 411104 9365 Erinaceus europaeus ENSEEUG00000000616
13616 Monodelphis domestica ENSMODG00000006170 61853 Nomascus leucogenys ENSNLEG00000010047
132908 Pteropus vampyrus ENSPVAG00000004599 9823 Sus scrofa ENSSSCG00000007110
31033 Takifugu rubripes ENSTRUG00000007924 9913 Bos taurus ENSBTAG00000011312
9615 Canis familiaris ENSCAFG00000031316 7955 Danio rerio ENSDARG00000075107
10020 Dipodomys ordii ENSDORG00000007972 9371 Echinops telfairi ENSETEG00000001746
69293 Gasterosteus aculeatus ENSGACG00000006999 9595 Gorilla gorilla ENSGGOG00000027030
8049 Gadus morhua ENSGMOG00000018925 7897 Latimeria chalumnae ENSLACG00000009870
9544 Macaca mulatta ENSMMUG00000011409 9258 Ornithorhynchus anatinus ENSOANG00000002007
8128 Oreochromis niloticus ENSONIG00000018724 9813 Procavia capensis ENSPCAG00000008298
7757 Petromyzon marinus ENSPMAG00000000997 9601 Pongo abelii ENSPPYG00000010756
37347 Tupaia belangeri ENSTBEG00000015943 99883 Tetraodon nigroviridis ENSTNIG00000016893