Basic Information
Gene ID 2294 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name FOXF1; FKHL5, FREAC1
Full Name Forkhead box protein F1
Organism Homo sapiens [9606]

Cross Reference
UniProt Q12946 UniGene Hs.155591
PDB NULL OMIM 601089
KEGG hsa:2294 UCSC uc002fjl.3

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 9606.ENSP00000262426

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000262426 Gene3D G3DSA:1.10.10.10 IPR011991 38 134 1.10e-39 Winged helix-turn-helix DNA-binding domain
ENSP00000262426 Pfam PF00250 IPR001766 48 140 1.10e-38 Transcription factor, fork head
ENSP00000262426 PRINTS PR00053 IPR001766 48 61 1.70e-22 Transcription factor, fork head
ENSP00000262426 PRINTS PR00053 IPR001766 69 86 1.70e-22 Transcription factor, fork head
ENSP00000262426 PRINTS PR00053 IPR001766 92 109 1.70e-22 Transcription factor, fork head
ENSP00000262426 ProSitePatterns PS00657 IPR018122 48 61 - Transcription factor, fork head, conserved site
ENSP00000262426 ProSitePatterns PS00658 IPR018122 92 98 - Transcription factor, fork head, conserved site
ENSP00000262426 ProSiteProfiles PS50039 IPR001766 48 142 0.00e-00 Transcription factor, fork head
ENSP00000262426 SMART SM00339 IPR001766 46 136 7.90e-62 Transcription factor, fork head

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000262426 PF00250 5.3e-39 Fork_head Fork head domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000262426 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSP00000262426 GO:0005634 cellular_component nucleus
ENSP00000262426 GO:0003677 molecular_function DNA binding
ENSP00000262426 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9986 Oryctolagus cuniculus 100341838 9483 Callithrix jacchus 100406681
30195 Bombus terrestris 100649771 143995 Megachile rotundata 100878921
10090 Mus musculus 14238 6239 Caenorhabditis elegans 172331
7425 Nasonia vitripennis 100117699 7070 Tribolium castaneum 100142613
10224 Saccoglossus kowalevskii 100303470 9601 Pongo abelii 100442608
7029 Acyrthosiphon pisum 100573371 8128 Oreochromis niloticus 100699611
132113 Bombus impatiens 100740244 10029 Cricetulus griseus 100760156
7463 Apis florea 100866104 7668 Strongylocentrotus purpuratus 100892692
34638 Metaseiulus occidentalis 100903565 9597 Pan paniscus 100969769
9555 Papio anubis 101023744 39432 Saimiri boliviensis 101027708
31033 Takifugu rubripes 101062107 9595 Gorilla gorilla 101127612
8090 Oryzias latipes 101171563 8083 Xiphophorus maculatus 102220431
7897 Latimeria chalumnae 102346994 7955 Danio rerio 566407
10116 Rattus norvegicus 687536 9544 Macaca mulatta 694454
28377 Anolis carolinensis ENSACAG00000017732 9646 Ailuropoda melanoleuca ENSAMEG00000018266
9913 Bos taurus ENSBTAG00000000009 9615 Canis familiaris ENSCAFG00000019918
7719 Ciona intestinalis ENSCING00000009387 10141 Cavia porcellus ENSCPOG00000000954
51511 Ciona savignyi ENSCSAVG00000008978 10020 Dipodomys ordii ENSDORG00000001552
9796 Equus caballus ENSECAG00000020094 9365 Erinaceus europaeus ENSEEUG00000002843
9685 Felis catus ENSFCAG00000030557 69293 Gasterosteus aculeatus ENSGACG00000015956
8049 Gadus morhua ENSGMOG00000003941 9785 Loxodonta africana ENSLAFG00000002036
9315 Macropus eugenii ENSMEUG00000008968 9103 Meleagris gallopavo ENSMGAG00000017424
30608 Microcebus murinus ENSMICG00000010236 13616 Monodelphis domestica ENSMODG00000004542
9669 Mustela putorius furo ENSMPUG00000008619 30611 Otolemur garnettii ENSOGAG00000011910
9813 Procavia capensis ENSPCAG00000004953 7757 Petromyzon marinus ENSPMAG00000004470
13735 Pelodiscus sinensis ENSPSIG00000004712 9598 Pan troglodytes ENSPTRG00000017662
132908 Pteropus vampyrus ENSPVAG00000007544 9305 Sarcophilus harrisii ENSSHAG00000012906
9823 Sus scrofa ENSSSCG00000000992 43179 Ictidomys tridecemlineatus ENSSTOG00000020735
99883 Tetraodon nigroviridis ENSTNIG00000009284 9478 Tarsius syrichta ENSTSYG00000010094
9739 Tursiops truncatus ENSTTRG00000005881 8364 Xenopus tropicalis ENSXETG00000003565
7227 Drosophila melanogaster 38766 7460 Apis mellifera 726050
9031 Gallus gallus ENSGALG00000005728 59463 Myotis lucifugus ENSMLUG00000030088
9258 Ornithorhynchus anatinus ENSOANG00000007633 9978 Ochotona princeps ENSOPRG00000010077
59729 Taeniopygia guttata ENSTGUG00000004150