Basic Information
Gene ID 2353 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name FOS; G0S7
Full Name Proto-oncogene c-Fos
Organism Homo sapiens [9606]

Cross Reference
UniProt P01100 UniGene Hs.25647
PDB 1S9K OMIM 164810
KEGG hsa:2353 UCSC uc001xrn.3

Protein Interactions
DIP DIP-1047N
IntAct P01100
MINT MINT-105814
STRING 9606.ENSP00000306245

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_005243 Pfam PF00170 IPR004827 135 194 3.70e-09 Basic-leucine zipper domain
NP_005243 PRINTS PR00042 IPR000837 130 146 5.50e-54 Fos transforming protein
NP_005243 PRINTS PR00042 IPR000837 147 163 5.50e-54 Fos transforming protein
NP_005243 PRINTS PR00042 IPR000837 165 186 5.50e-54 Fos transforming protein
NP_005243 PRINTS PR00042 IPR000837 186 209 5.50e-54 Fos transforming protein
NP_005243 PRINTS PR00042 IPR000837 62 79 5.50e-54 Fos transforming protein
NP_005243 ProSitePatterns PS00036 IPR004827 143 157 - Basic-leucine zipper domain
NP_005243 ProSiteProfiles PS50217 IPR004827 137 200 0.00e-00 Basic-leucine zipper domain
NP_005243 SMART SM00338 IPR004827 135 199 5.80e-18 Basic-leucine zipper domain

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_005243 PF00170 2.5e-09 bZIP_1 bZIP transcription factor
NP_005243 PF07716 6.4e-08 bZIP_2 Basic region leucine zipper
NP_005243 PF03131 3.6e-05 bZIP_Maf bZIP Maf transcription factor

Gene Ontology Annotation
Protein Entry Name Space Description
NP_005243 GO:0006355 biological_process regulation of transcription, DNA-templated
NP_005243 GO:0005634 cellular_component nucleus
NP_005243 GO:0005737 cellular_component cytoplasm
NP_005243 GO:0005783 cellular_component endoplasmic reticulum
NP_005243 GO:0005829 cellular_component cytosol
NP_005243 GO:0003677 molecular_function DNA binding
NP_005243 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
NP_005243 GO:0043565 molecular_function sequence-specific DNA binding