Basic Information
Gene ID 2494 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name NR5A2; B1F, CPF, FTF
Full Name Nuclear receptor subfamily 5 group A member 2
Organism Homo sapiens [9606]

Cross Reference
UniProt O00482 UniGene Hs.33446
PDB 4IS8 OMIM 604453
KEGG hsa:2494 UCSC uc001gvb.4

Protein Interactions
DIP DIP-37952N
IntAct O00482
MINT MINT-2997724
STRING 9606.ENSP00000356331

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000356331 Gene3D G3DSA:1.10.565.10 IPR008946 295 540 1.90e-85 Nuclear hormone receptor, ligand-binding
ENSP00000356331 Gene3D G3DSA:3.30.50.10 IPR013088 84 166 9.70e-33 Zinc finger, NHR/GATA-type
ENSP00000356331 Pfam PF00104 IPR000536 325 517 1.30e-33 Nuclear hormone receptor, ligand-binding, core
ENSP00000356331 Pfam PF00105 IPR001628 85 152 4.20e-32 Zinc finger, nuclear hormone receptor-type
ENSP00000356331 PIRSF PIRSF002530 IPR016355 10 541 0.00e-00 Steroidogenic factor 1
ENSP00000356331 PRINTS PR00047 IPR001628 102 117 3.00e-18 Zinc finger, nuclear hormone receptor-type
ENSP00000356331 PRINTS PR00047 IPR001628 135 143 3.00e-18 Zinc finger, nuclear hormone receptor-type
ENSP00000356331 PRINTS PR00047 IPR001628 143 151 3.00e-18 Zinc finger, nuclear hormone receptor-type
ENSP00000356331 PRINTS PR00047 IPR001628 86 102 3.00e-18 Zinc finger, nuclear hormone receptor-type
ENSP00000356331 PRINTS PR00398 IPR001723 147 157 9.80e-27 Steroid hormone receptor
ENSP00000356331 PRINTS PR00398 IPR001723 348 369 9.80e-27 Steroid hormone receptor
ENSP00000356331 PRINTS PR00398 IPR001723 369 385 9.80e-27 Steroid hormone receptor
ENSP00000356331 PRINTS PR00398 IPR001723 441 456 9.80e-27 Steroid hormone receptor
ENSP00000356331 PRINTS PR00398 IPR001723 498 515 9.80e-27 Steroid hormone receptor
ENSP00000356331 ProSitePatterns PS00031 IPR001628 86 112 - Zinc finger, nuclear hormone receptor-type
ENSP00000356331 ProSiteProfiles PS51030 IPR001628 83 158 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSP00000356331 SMART SM00399 IPR001628 83 154 1.80e-43 Zinc finger, nuclear hormone receptor-type
ENSP00000356331 SMART SM00430 IPR000536 347 510 4.10e-46 Nuclear hormone receptor, ligand-binding, core
ENSP00000356331 SUPERFAMILY SSF48508 IPR008946 152 166 0.00e-00 Nuclear hormone receptor, ligand-binding
ENSP00000356331 SUPERFAMILY SSF48508 IPR008946 301 539 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000356331 PF00104 8.6e-34 Hormone_recep Ligand-binding domain of nuclear hormone receptor
ENSP00000356331 PF00105 2.5e-32 zf-C4 Zinc finger, C4 type (two domains)

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000356331 GO:0005634 cellular_component nucleus
ENSP00000356331 GO:0003677 molecular_function DNA binding
ENSP00000356331 GO:0003707 molecular_function steroid hormone receptor activity
ENSP00000356331 GO:0008270 molecular_function zinc ion binding
ENSP00000356331 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9986 Oryctolagus cuniculus 100008896 7029 Acyrthosiphon pisum 100162562
8128 Oreochromis niloticus 100534561 30195 Bombus terrestris 100649882
132113 Bombus impatiens 100741012 7463 Apis florea 100868036
34638 Metaseiulus occidentalis 100901258 9597 Pan paniscus 100988166
39432 Saimiri boliviensis 101037961 9595 Gorilla gorilla 101142071
9669 Mustela putorius furo 101682388 7425 Nasonia vitripennis 100115727
10224 Saccoglossus kowalevskii 100303475 10029 Cricetulus griseus 100766752
9555 Papio anubis 101000895 13735 Pelodiscus sinensis 102449894
10090 Mus musculus 26424 7227 Drosophila melanogaster 40045
9615 Canis familiaris 490252 7668 Strongylocentrotus purpuratus 587072
7070 Tribolium castaneum 658929 7460 Apis mellifera 726450
28377 Anolis carolinensis ENSACAG00000006301 9358 Choloepus hoffmanni ENSCHOG00000004407
7719 Ciona intestinalis ENSCING00000004593 51511 Ciona savignyi ENSCSAVG00000000069
10020 Dipodomys ordii ENSDORG00000006587 9365 Erinaceus europaeus ENSEEUG00000012910
9371 Echinops telfairi ENSETEG00000003796 69293 Gasterosteus aculeatus ENSGACG00000008896
8049 Gadus morhua ENSGMOG00000001147 9785 Loxodonta africana ENSLAFG00000008809
9103 Meleagris gallopavo ENSMGAG00000005896 30608 Microcebus murinus ENSMICG00000011337
9544 Macaca mulatta ENSMMUG00000011185 61853 Nomascus leucogenys ENSNLEG00000018066
9258 Ornithorhynchus anatinus ENSOANG00000005642 9978 Ochotona princeps ENSOPRG00000016263
8090 Oryzias latipes ENSORLG00000006933 7757 Petromyzon marinus ENSPMAG00000001450
9601 Pongo abelii ENSPPYG00000000379 10116 Rattus norvegicus ENSRNOG00000000653
42254 Sorex araneus ENSSARG00000009752 9823 Sus scrofa ENSSSCG00000024975
43179 Ictidomys tridecemlineatus ENSSTOG00000024925 37347 Tupaia belangeri ENSTBEG00000008925
59729 Taeniopygia guttata ENSTGUG00000004419 9478 Tarsius syrichta ENSTSYG00000005740
9739 Tursiops truncatus ENSTTRG00000003256 30538 Vicugna pacos ENSVPAG00000001644
8083 Xiphophorus maculatus ENSXMAG00000006009 9598 Pan troglodytes 469631
10141 Cavia porcellus ENSCPOG00000008775 7955 Danio rerio ENSDARG00000042556
9685 Felis catus ENSFCAG00000012604 9031 Gallus gallus ENSGALG00000002182
7897 Latimeria chalumnae ENSLACG00000000386 59463 Myotis lucifugus ENSMLUG00000013283
132908 Pteropus vampyrus ENSPVAG00000004687 9305 Sarcophilus harrisii ENSSHAG00000011399
99883 Tetraodon nigroviridis ENSTNIG00000004616 31033 Takifugu rubripes ENSTRUG00000009548
8364 Xenopus tropicalis ENSXETG00000000314