Basic Information
Gene ID 2516 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name NR5A1; AD4BP, FTZF1, SF1
Full Name Steroidogenic factor 1
Organism Homo sapiens [9606]

Cross Reference
UniProt Q13285 UniGene Hs.495108
PDB 1ZDT OMIM 613957
KEGG hsa:2516 UCSC uc004boo.1

Protein Interactions
DIP NULL
IntAct Q13285
MINT MINT-215481
STRING 9606.ENSP00000362690

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000362690 Gene3D G3DSA:1.10.565.10 IPR008946 216 460 1.50e-69 Nuclear hormone receptor, ligand-binding
ENSP00000362690 Gene3D G3DSA:3.30.50.10 IPR013088 11 93 4.10e-32 Zinc finger, NHR/GATA-type
ENSP00000362690 Pfam PF00104 IPR000536 259 436 1.00e-22 Nuclear hormone receptor, ligand-binding, core
ENSP00000362690 Pfam PF00105 IPR001628 12 79 8.30e-32 Zinc finger, nuclear hormone receptor-type
ENSP00000362690 PIRSF PIRSF002530 IPR016355 1 461 3.80e-223 Steroidogenic factor 1
ENSP00000362690 PRINTS PR00047 IPR001628 13 29 3.80e-18 Zinc finger, nuclear hormone receptor-type
ENSP00000362690 PRINTS PR00047 IPR001628 29 44 3.80e-18 Zinc finger, nuclear hormone receptor-type
ENSP00000362690 PRINTS PR00047 IPR001628 62 70 3.80e-18 Zinc finger, nuclear hormone receptor-type
ENSP00000362690 PRINTS PR00047 IPR001628 70 78 3.80e-18 Zinc finger, nuclear hormone receptor-type
ENSP00000362690 PRINTS PR00398 IPR001723 268 289 1.80e-25 Steroid hormone receptor
ENSP00000362690 PRINTS PR00398 IPR001723 289 305 1.80e-25 Steroid hormone receptor
ENSP00000362690 PRINTS PR00398 IPR001723 361 376 1.80e-25 Steroid hormone receptor
ENSP00000362690 PRINTS PR00398 IPR001723 418 435 1.80e-25 Steroid hormone receptor
ENSP00000362690 PRINTS PR00398 IPR001723 74 84 1.80e-25 Steroid hormone receptor
ENSP00000362690 ProSitePatterns PS00031 IPR001628 13 39 - Zinc finger, nuclear hormone receptor-type
ENSP00000362690 ProSiteProfiles PS51030 IPR001628 10 85 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSP00000362690 SMART SM00399 IPR001628 10 81 8.10e-41 Zinc finger, nuclear hormone receptor-type
ENSP00000362690 SMART SM00430 IPR000536 267 430 1.20e-37 Nuclear hormone receptor, ligand-binding, core
ENSP00000362690 SUPERFAMILY SSF48508 IPR008946 220 459 0.00e-00 Nuclear hormone receptor, ligand-binding
ENSP00000362690 SUPERFAMILY SSF48508 IPR008946 59 94 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000362690 PF00105 4.1e-32 zf-C4 Zinc finger, C4 type (two domains)
ENSP00000362690 PF00104 6.5e-23 Hormone_recep Ligand-binding domain of nuclear hormone receptor

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000362690 GO:0005634 cellular_component nucleus
ENSP00000362690 GO:0003677 molecular_function DNA binding
ENSP00000362690 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSP00000362690 GO:0003707 molecular_function steroid hormone receptor activity
ENSP00000362690 GO:0008270 molecular_function zinc ion binding
ENSP00000362690 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
43179 Ictidomys tridecemlineatus 101971101 61853 Nomascus leucogenys 100595498
143995 Megachile rotundata 100881489 30611 Otolemur garnettii 100943946
9597 Pan paniscus 100993289 9555 Papio anubis 101016016
39432 Saimiri boliviensis 101054348 9595 Gorilla gorilla 101153036
9913 Bos taurus 281948 9646 Ailuropoda melanoleuca ENSAMEG00000011166
9615 Canis familiaris ENSCAFG00000023086 9483 Callithrix jacchus ENSCJAG00000006624
10141 Cavia porcellus ENSCPOG00000022305 9685 Felis catus ENSFCAG00000022552
30608 Microcebus murinus ENSMICG00000002907 59463 Myotis lucifugus ENSMLUG00000005775
13616 Monodelphis domestica ENSMODG00000019746 9669 Mustela putorius furo ENSMPUG00000013973
9986 Oryctolagus cuniculus ENSOCUG00000007848 9978 Ochotona princeps ENSOPRG00000016678
9739 Tursiops truncatus ENSTTRG00000017390 9796 Equus caballus ENSECAG00000013752
9365 Erinaceus europaeus ENSEEUG00000003357 9315 Macropus eugenii ENSMEUG00000006583
9813 Procavia capensis ENSPCAG00000012467 132908 Pteropus vampyrus ENSPVAG00000000217
9305 Sarcophilus harrisii ENSSHAG00000016609