Basic Information
Gene ID 27332 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name ZNF638; NP220, ZFML
Full Name Zinc finger protein 638
Organism Homo sapiens [9606]

Cross Reference
UniProt Q14966 UniGene Hs.732823
PDB NULL OMIM 614349
KEGG hsa:27332 UCSC uc002sib.1

Protein Interactions
DIP DIP-42386N
IntAct Q14966
MINT MINT-1439144
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000264447 Gene3D G3DSA:3.30.70.330 IPR012677 667 758 2.60e-15 Nucleotide-binding, alpha-beta plait
ENSP00000264447 Gene3D G3DSA:3.30.70.330 IPR012677 898 983 2.90e-07 Nucleotide-binding, alpha-beta plait
ENSP00000264447 Gene3D G3DSA:3.30.70.330 IPR012677 998 1081 2.30e-08 Nucleotide-binding, alpha-beta plait
ENSP00000264447 ProSitePatterns PS00028 IPR007087 1930 1952 - Zinc finger, C2H2
ENSP00000264447 ProSitePatterns PS00028 IPR007087 428 450 - Zinc finger, C2H2
ENSP00000264447 ProSiteProfiles PS50102 IPR000504 676 746 0.00e-00 RNA recognition motif domain
ENSP00000264447 ProSiteProfiles PS50171 IPR000690 1928 1958 0.00e-00 Zinc finger, C2H2-type matrin
ENSP00000264447 SMART SM00355 IPR015880 1928 1952 6.20e-03 Zinc finger, C2H2-like
ENSP00000264447 SMART SM00355 IPR015880 426 450 4.60e-02 Zinc finger, C2H2-like
ENSP00000264447 SMART SM00360 IPR000504 677 747 7.70e-09 RNA recognition motif domain
ENSP00000264447 SMART SM00451 IPR003604 1925 1959 2.70e-10 Zinc finger, U1-type
ENSP00000264447 SMART SM00451 IPR003604 423 457 2.70e-02 Zinc finger, U1-type

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000264447 PF14259 1.1e-19 RRM_6 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain)
ENSP00000264447 PF13893 1.2e-18 RRM_5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
ENSP00000264447 PF00076 1.8e-08 RRM_1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
ENSP00000264447 PF12171 6.4e-05 zf-C2H2_jaz Zinc-finger double-stranded RNA-binding

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000264447 GO:0006351 biological_process transcription, DNA-templated
ENSP00000264447 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSP00000264447 GO:0008380 biological_process RNA splicing
ENSP00000264447 GO:0005634 cellular_component nucleus
ENSP00000264447 GO:0005654 cellular_component nucleoplasm
ENSP00000264447 GO:0005730 cellular_component nucleolus
ENSP00000264447 GO:0005737 cellular_component cytoplasm
ENSP00000264447 GO:0016607 cellular_component nuclear speck
ENSP00000264447 GO:0043231 cellular_component intracellular membrane-bounded organelle
ENSP00000264447 GO:0000166 molecular_function nucleotide binding
ENSP00000264447 GO:0003690 molecular_function double-stranded DNA binding
ENSP00000264447 GO:0003723 molecular_function RNA binding
ENSP00000264447 GO:0008270 molecular_function zinc ion binding
ENSP00000264447 GO:0044822 molecular_function poly(A) RNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
39432 Saimiri boliviensis 101039331 61853 Nomascus leucogenys 100584030
9597 Pan paniscus 100986153 9555 Papio anubis 101000316
9913 Bos taurus ENSBTAG00000009242 9358 Choloepus hoffmanni ENSCHOG00000013922
9483 Callithrix jacchus ENSCJAG00000019436 10141 Cavia porcellus ENSCPOG00000010101
9796 Equus caballus ENSECAG00000007715 9365 Erinaceus europaeus ENSEEUG00000013424
9685 Felis catus ENSFCAG00000004356 9595 Gorilla gorilla ENSGGOG00000012511
30608 Microcebus murinus ENSMICG00000005419 59463 Myotis lucifugus ENSMLUG00000011904
9544 Macaca mulatta ENSMMUG00000007175 13616 Monodelphis domestica ENSMODG00000010964
9669 Mustela putorius furo ENSMPUG00000007422 30611 Otolemur garnettii ENSOGAG00000001152
9978 Ochotona princeps ENSOPRG00000011644 9813 Procavia capensis ENSPCAG00000014342
9601 Pongo abelii ENSPPYG00000029854 13735 Pelodiscus sinensis ENSPSIG00000011267
132908 Pteropus vampyrus ENSPVAG00000008368 42254 Sorex araneus ENSSARG00000000956
9823 Sus scrofa ENSSSCG00000023047 43179 Ictidomys tridecemlineatus ENSSTOG00000003995
37347 Tupaia belangeri ENSTBEG00000004110 9739 Tursiops truncatus ENSTTRG00000014220
30538 Vicugna pacos ENSVPAG00000004117 9361 Dasypus novemcinctus ENSDNOG00000002173
9785 Loxodonta africana ENSLAFG00000008513 9986 Oryctolagus cuniculus ENSOCUG00000010045
9478 Tarsius syrichta ENSTSYG00000012849