Basic Information
Gene ID 2736 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name GLI2; THP
Full Name Zinc finger protein GLI2
Organism Homo sapiens [9606]

Cross Reference
UniProt P10070 UniGene Hs.111867
PDB NULL OMIM 610829
KEGG hsa:2736 UCSC uc002tmu.4

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 9606.ENSP00000354586

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000354586 Gene3D G3DSA:3.30.160.60 IPR013087 436 468 2.10e-17 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000354586 Gene3D G3DSA:3.30.160.60 IPR013087 469 496 3.90e-06 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000354586 Gene3D G3DSA:3.30.160.60 IPR013087 497 531 8.50e-22 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000354586 Gene3D G3DSA:3.30.160.60 IPR013087 532 561 6.80e-15 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000354586 Gene3D G3DSA:3.30.160.60 IPR013087 562 591 3.00e-16 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000354586 Pfam PF00096 IPR007087 439 462 3.70e-02 Zinc finger, C2H2
ENSP00000354586 Pfam PF00096 IPR007087 564 589 1.40e-03 Zinc finger, C2H2
ENSP00000354586 ProSitePatterns PS00028 IPR007087 439 462 - Zinc finger, C2H2
ENSP00000354586 ProSitePatterns PS00028 IPR007087 505 527 - Zinc finger, C2H2
ENSP00000354586 ProSitePatterns PS00028 IPR007087 535 558 - Zinc finger, C2H2
ENSP00000354586 ProSitePatterns PS00028 IPR007087 566 589 - Zinc finger, C2H2
ENSP00000354586 ProSiteProfiles PS50157 IPR007087 475 502 0.00e-00 Zinc finger, C2H2
ENSP00000354586 ProSiteProfiles PS50157 IPR007087 503 532 0.00e-00 Zinc finger, C2H2
ENSP00000354586 ProSiteProfiles PS50157 IPR007087 533 563 0.00e-00 Zinc finger, C2H2
ENSP00000354586 ProSiteProfiles PS50157 IPR007087 564 594 0.00e-00 Zinc finger, C2H2
ENSP00000354586 SMART SM00355 IPR015880 437 462 1.80e-03 Zinc finger, C2H2-like
ENSP00000354586 SMART SM00355 IPR015880 470 497 2.20e-02 Zinc finger, C2H2-like
ENSP00000354586 SMART SM00355 IPR015880 503 527 6.80e-06 Zinc finger, C2H2-like
ENSP00000354586 SMART SM00355 IPR015880 533 558 1.40e-05 Zinc finger, C2H2-like
ENSP00000354586 SMART SM00355 IPR015880 564 589 6.20e-07 Zinc finger, C2H2-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000354586 PF00096 3.3e-15 zf-C2H2 Zinc finger, C2H2 type
ENSP00000354586 PF13465 7.6e-13 zf-H2C2_2 Zinc-finger double domain
ENSP00000354586 PF13894 2.1e-07 zf-C2H2_4 C2H2-type zinc finger

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000354586 GO:0006351 biological_process transcription, DNA-templated
ENSP00000354586 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSP00000354586 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSP00000354586 GO:0005634 cellular_component nucleus
ENSP00000354586 GO:0005737 cellular_component cytoplasm
ENSP00000354586 GO:0003677 molecular_function DNA binding
ENSP00000354586 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSP00000354586 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
30195 Bombus terrestris 100649327 7425 Nasonia vitripennis 100118465
9986 Oryctolagus cuniculus 100355047 7029 Acyrthosiphon pisum 100575006
400682 Amphimedon queenslandica 100631915 8128 Oreochromis niloticus 100709465
132113 Bombus impatiens 100746944 10029 Cricetulus griseus 100762738
7463 Apis florea 100869111 143995 Megachile rotundata 100882254
9597 Pan paniscus 100973775 9555 Papio anubis 101020631
39432 Saimiri boliviensis 101053117 8083 Xiphophorus maculatus 102236609
13735 Pelodiscus sinensis 102447306 10090 Mus musculus 14634
10116 Rattus norvegicus 304729 9031 Gallus gallus 420769
7227 Drosophila melanogaster 43767 9598 Pan troglodytes 459582
7460 Apis mellifera 551746 7668 Strongylocentrotus purpuratus 580371
7070 Tribolium castaneum 658653 28377 Anolis carolinensis ENSACAG00000004133
9646 Ailuropoda melanoleuca ENSAMEG00000008708 9913 Bos taurus ENSBTAG00000011682
9615 Canis familiaris ENSCAFG00000004821 9358 Choloepus hoffmanni ENSCHOG00000003774
7719 Ciona intestinalis ENSCING00000012018 9483 Callithrix jacchus ENSCJAG00000013342
10141 Cavia porcellus ENSCPOG00000015189 51511 Ciona savignyi ENSCSAVG00000009575
7955 Danio rerio ENSDARG00000025641 9361 Dasypus novemcinctus ENSDNOG00000008730
10020 Dipodomys ordii ENSDORG00000008299 9796 Equus caballus ENSECAG00000008016
9365 Erinaceus europaeus ENSEEUG00000006153 9371 Echinops telfairi ENSETEG00000020154
9685 Felis catus ENSFCAG00000014531 69293 Gasterosteus aculeatus ENSGACG00000001547
9595 Gorilla gorilla ENSGGOG00000009653 8049 Gadus morhua ENSGMOG00000010335
7897 Latimeria chalumnae ENSLACG00000017364 9785 Loxodonta africana ENSLAFG00000009839
9315 Macropus eugenii ENSMEUG00000013134 9103 Meleagris gallopavo ENSMGAG00000011872
30608 Microcebus murinus ENSMICG00000010785 59463 Myotis lucifugus ENSMLUG00000015711
9544 Macaca mulatta ENSMMUG00000001868 13616 Monodelphis domestica ENSMODG00000000245
9669 Mustela putorius furo ENSMPUG00000000986 61853 Nomascus leucogenys ENSNLEG00000003160
9258 Ornithorhynchus anatinus ENSOANG00000009722 9978 Ochotona princeps ENSOPRG00000011185
9813 Procavia capensis ENSPCAG00000001704 7757 Petromyzon marinus ENSPMAG00000007806
9601 Pongo abelii ENSPPYG00000012778 132908 Pteropus vampyrus ENSPVAG00000002518
9305 Sarcophilus harrisii ENSSHAG00000004233 9823 Sus scrofa ENSSSCG00000015733
43179 Ictidomys tridecemlineatus ENSSTOG00000004582 37347 Tupaia belangeri ENSTBEG00000006673
59729 Taeniopygia guttata ENSTGUG00000004599 99883 Tetraodon nigroviridis ENSTNIG00000017828
31033 Takifugu rubripes ENSTRUG00000001954 9478 Tarsius syrichta ENSTSYG00000009406
9739 Tursiops truncatus ENSTTRG00000002058 30538 Vicugna pacos ENSVPAG00000000048
8364 Xenopus tropicalis ENSXETG00000011189 30611 Otolemur garnettii ENSOGAG00000032438
8090 Oryzias latipes ENSORLG00000001328