Basic Information
Gene ID 2737 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name GLI3
Full Name Transcriptional activator GLI3
Organism Homo sapiens [9606]

Cross Reference
UniProt P10071 UniGene Hs.21509
PDB 4BLD OMIM 175700
KEGG hsa:2737 UCSC uc011kbg.2

Protein Interactions
DIP NULL
IntAct P10071
MINT MINT-189869
STRING 9606.ENSP00000379255

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_000159 Gene3D G3DSA:3.30.160.60 IPR013087 479 511 5.40e-18 Zinc finger C2H2-type/integrase DNA-binding domain
NP_000159 Gene3D G3DSA:3.30.160.60 IPR013087 512 539 4.50e-06 Zinc finger C2H2-type/integrase DNA-binding domain
NP_000159 Gene3D G3DSA:3.30.160.60 IPR013087 540 574 1.00e-21 Zinc finger C2H2-type/integrase DNA-binding domain
NP_000159 Gene3D G3DSA:3.30.160.60 IPR013087 575 604 6.60e-15 Zinc finger C2H2-type/integrase DNA-binding domain
NP_000159 Gene3D G3DSA:3.30.160.60 IPR013087 605 634 1.10e-16 Zinc finger C2H2-type/integrase DNA-binding domain
NP_000159 Pfam PF00096 IPR007087 607 632 6.50e-04 Zinc finger, C2H2
NP_000159 ProSitePatterns PS00028 IPR007087 482 505 - Zinc finger, C2H2
NP_000159 ProSitePatterns PS00028 IPR007087 548 570 - Zinc finger, C2H2
NP_000159 ProSitePatterns PS00028 IPR007087 578 601 - Zinc finger, C2H2
NP_000159 ProSitePatterns PS00028 IPR007087 609 632 - Zinc finger, C2H2
NP_000159 ProSiteProfiles PS50157 IPR007087 480 512 0.00e-00 Zinc finger, C2H2
NP_000159 ProSiteProfiles PS50157 IPR007087 518 545 0.00e-00 Zinc finger, C2H2
NP_000159 ProSiteProfiles PS50157 IPR007087 546 575 0.00e-00 Zinc finger, C2H2
NP_000159 ProSiteProfiles PS50157 IPR007087 576 606 0.00e-00 Zinc finger, C2H2
NP_000159 ProSiteProfiles PS50157 IPR007087 607 637 0.00e-00 Zinc finger, C2H2
NP_000159 SMART SM00355 IPR015880 480 505 9.20e-04 Zinc finger, C2H2-like
NP_000159 SMART SM00355 IPR015880 513 540 4.10e-03 Zinc finger, C2H2-like
NP_000159 SMART SM00355 IPR015880 546 570 1.10e-05 Zinc finger, C2H2-like
NP_000159 SMART SM00355 IPR015880 576 601 1.40e-05 Zinc finger, C2H2-like
NP_000159 SMART SM00355 IPR015880 607 632 4.80e-07 Zinc finger, C2H2-like

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_000159 PF00096 4.9e-18 zf-C2H2 Zinc finger, C2H2 type
NP_000159 PF13465 3.1e-15 zf-H2C2_2 Zinc-finger double domain
NP_000159 PF13894 4.6e-08 zf-C2H2_4 C2H2-type zinc finger

Gene Ontology Annotation
Protein Entry Name Space Description
NP_000159 GO:0006351 biological_process transcription, DNA-templated
NP_000159 GO:0006355 biological_process regulation of transcription, DNA-templated
NP_000159 GO:0045893 biological_process positive regulation of transcription, DNA-templated
NP_000159 GO:0005634 cellular_component nucleus
NP_000159 GO:0005737 cellular_component cytoplasm
NP_000159 GO:0003677 molecular_function DNA binding
NP_000159 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
NP_000159 GO:0046872 molecular_function metal ion binding