Basic Information
Gene ID 2968 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name GTF2H4
Full Name General transcription factor IIH subunit 4
Organism Homo sapiens [9606]

Cross Reference
UniProt Q92759 UniGene Hs.485070
PDB NULL OMIM 601760
KEGG hsa:2968 UCSC uc003nsa.1

Protein Interactions
DIP DIP-48376N
IntAct Q92759
MINT MINT-3049325
STRING 9606.ENSP00000259895

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000403156 PANTHER PTHR13152 IPR004598 7 462 0.00e-00 Transcription factor TFIIH subunit p52/Tfb2
ENSP00000403156 Pfam PF03849 IPR004598 21 374 7.80e-138 Transcription factor TFIIH subunit p52/Tfb2
ENSP00000403156 TIGRFAM TIGR00625 IPR004598 18 460 7.20e-233 Transcription factor TFIIH subunit p52/Tfb2

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000403156 PF03849 0 Tfb2 Transcription factor Tfb2
ENSP00000403156 PF13625 4.1e-07 Helicase_C_3 Helicase conserved C-terminal domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000403156 GO:0006200 biological_process ATP catabolic process
ENSP00000403156 GO:0006281 biological_process DNA repair
ENSP00000403156 GO:0006289 biological_process nucleotide-excision repair
ENSP00000403156 GO:0006366 biological_process transcription from RNA polymerase II promoter
ENSP00000403156 GO:0006468 biological_process protein phosphorylation
ENSP00000403156 GO:0000439 cellular_component core TFIIH complex
ENSP00000403156 GO:0005675 cellular_component holo TFIIH complex
ENSP00000403156 GO:0004003 molecular_function ATP-dependent DNA helicase activity
ENSP00000403156 GO:0004672 molecular_function protein kinase activity
ENSP00000403156 GO:0008094 molecular_function DNA-dependent ATPase activity
ENSP00000403156 GO:0008353 molecular_function RNA polymerase II carboxy-terminal domain kinase activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9913 Bos taurus 100137723 7029 Acyrthosiphon pisum 100160821
61853 Nomascus leucogenys 100602212 30195 Bombus terrestris 100648701
9785 Loxodonta africana 100663281 132113 Bombus impatiens 100747453
9615 Canis familiaris 100856712 34638 Metaseiulus occidentalis 100908407
9595 Gorilla gorilla 101135417 10090 Mus musculus 14885
10116 Rattus norvegicus 294236 7425 Nasonia vitripennis 100118816
6087 Hydra magnipapillata 100211920 28377 Anolis carolinensis 100556108
400682 Amphimedon queenslandica 100632485 7463 Apis florea 100871254
143995 Megachile rotundata 100875263 9685 Felis catus 101097482
43179 Ictidomys tridecemlineatus 101967928 8083 Xiphophorus maculatus 102223591
7460 Apis mellifera 412010 9358 Choloepus hoffmanni ENSCHOG00000001840
7719 Ciona intestinalis ENSCING00000007295 51511 Ciona savignyi ENSCSAVG00000000936
8049 Gadus morhua ENSGMOG00000008479 7897 Latimeria chalumnae ENSLACG00000008796
9315 Macropus eugenii ENSMEUG00000014465 30611 Otolemur garnettii ENSOGAG00000026192
8128 Oreochromis niloticus ENSONIG00000004743 13735 Pelodiscus sinensis ENSPSIG00000006675
9739 Tursiops truncatus ENSTTRG00000012237 30538 Vicugna pacos ENSVPAG00000003700
7227 Drosophila melanogaster 39688 7668 Strongylocentrotus purpuratus 591457
7070 Tribolium castaneum 659751 9646 Ailuropoda melanoleuca ENSAMEG00000013069
9483 Callithrix jacchus ENSCJAG00000019826 7955 Danio rerio ENSDARG00000036071
10020 Dipodomys ordii ENSDORG00000008515 69293 Gasterosteus aculeatus ENSGACG00000001471
59463 Myotis lucifugus ENSMLUG00000026371 13616 Monodelphis domestica ENSMODG00000015851
9258 Ornithorhynchus anatinus ENSOANG00000010993 9986 Oryctolagus cuniculus ENSOCUG00000021496
9978 Ochotona princeps ENSOPRG00000018466 8090 Oryzias latipes ENSORLG00000010704
9813 Procavia capensis ENSPCAG00000006874 7757 Petromyzon marinus ENSPMAG00000007540
132908 Pteropus vampyrus ENSPVAG00000004195 99883 Tetraodon nigroviridis ENSTNIG00000003170
31033 Takifugu rubripes ENSTRUG00000014176 9478 Tarsius syrichta ENSTSYG00000009895
8364 Xenopus tropicalis ENSXETG00000007263