Basic Information
Gene ID 30012 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name TLX3; HOX11L2
Full Name T-cell leukemia homeobox protein 3
Organism Homo sapiens [9606]

Cross Reference
UniProt O43711 UniGene Hs.249125
PDB NULL OMIM 604640
KEGG hsa:30012 UCSC uc003mbf.3

Protein Interactions
DIP NULL
IntAct O43711
MINT NULL
STRING 9606.ENSP00000296921

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000296921 Gene3D G3DSA:1.10.10.60 IPR009057 159 226 3.10e-28 Homeodomain-like
ENSP00000296921 Pfam PF00046 IPR001356 167 223 9.00e-21 Homeobox domain
ENSP00000296921 PRINTS PR00024 IPR020479 188 199 5.10e-05 Homeodomain, metazoa
ENSP00000296921 PRINTS PR00024 IPR020479 203 213 5.10e-05 Homeodomain, metazoa
ENSP00000296921 PRINTS PR00024 IPR020479 213 222 5.10e-05 Homeodomain, metazoa
ENSP00000296921 ProSitePatterns PS00027 IPR017970 199 222 - Homeobox, conserved site
ENSP00000296921 ProSiteProfiles PS50071 IPR001356 164 224 0.00e-00 Homeobox domain
ENSP00000296921 SMART SM00389 IPR001356 166 228 5.70e-27 Homeobox domain
ENSP00000296921 SUPERFAMILY SSF46689 IPR009057 153 224 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000296921 PF00046 5.3e-21 Homeobox Homeobox domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000296921 GO:0005634 cellular_component nucleus
ENSP00000296921 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSP00000296921 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100116154 10224 Saccoglossus kowalevskii 100303489
400682 Amphimedon queenslandica 100642128 30195 Bombus terrestris 100648311
9785 Loxodonta africana 100663846 10141 Cavia porcellus 100724310
132113 Bombus impatiens 100740155 7463 Apis florea 100863936
34638 Metaseiulus occidentalis 100899298 30611 Otolemur garnettii 100948666
9597 Pan paniscus 100979317 9555 Papio anubis 101022319
39432 Saimiri boliviensis 101046973 9669 Mustela putorius furo 101673208
43179 Ictidomys tridecemlineatus 101954939 7029 Acyrthosiphon pisum 100573073
143995 Megachile rotundata 100875759 10090 Mus musculus 21908
7227 Drosophila melanogaster 42544 10020 Dipodomys ordii ENSDORG00000010859
9365 Erinaceus europaeus ENSEEUG00000014457 13616 Monodelphis domestica ENSMODG00000006508
9986 Oryctolagus cuniculus ENSOCUG00000000918 132908 Pteropus vampyrus ENSPVAG00000001727
9305 Sarcophilus harrisii ENSSHAG00000007060 59729 Taeniopygia guttata ENSTGUG00000014966
8364 Xenopus tropicalis 548656 7668 Strongylocentrotus purpuratus 576329
9615 Canis familiaris 608311 7070 Tribolium castaneum 663858
7460 Apis mellifera 724148 9598 Pan troglodytes 740883
28377 Anolis carolinensis ENSACAG00000015608 9646 Ailuropoda melanoleuca ENSAMEG00000003951
9913 Bos taurus ENSBTAG00000010003 7719 Ciona intestinalis ENSCING00000006177
9483 Callithrix jacchus ENSCJAG00000017424 51511 Ciona savignyi ENSCSAVG00000010706
7955 Danio rerio ENSDARG00000017615 9361 Dasypus novemcinctus ENSDNOG00000019906
9796 Equus caballus ENSECAG00000007840 9685 Felis catus ENSFCAG00000029037
69293 Gasterosteus aculeatus ENSGACG00000017882 9031 Gallus gallus ENSGALG00000002191
9595 Gorilla gorilla ENSGGOG00000006302 8049 Gadus morhua ENSGMOG00000014671
7897 Latimeria chalumnae ENSLACG00000013284 9315 Macropus eugenii ENSMEUG00000009488
9103 Meleagris gallopavo ENSMGAG00000010200 30608 Microcebus murinus ENSMICG00000008843
59463 Myotis lucifugus ENSMLUG00000016783 9544 Macaca mulatta ENSMMUG00000017667
61853 Nomascus leucogenys ENSNLEG00000000302 9258 Ornithorhynchus anatinus ENSOANG00000007318
8128 Oreochromis niloticus ENSONIG00000001402 9978 Ochotona princeps ENSOPRG00000007137
8090 Oryzias latipes ENSORLG00000003952 9813 Procavia capensis ENSPCAG00000004561
9601 Pongo abelii ENSPPYG00000016036 13735 Pelodiscus sinensis ENSPSIG00000008536
10116 Rattus norvegicus ENSRNOG00000004976 9823 Sus scrofa ENSSSCG00000016999
37347 Tupaia belangeri ENSTBEG00000008223 99883 Tetraodon nigroviridis ENSTNIG00000013058
31033 Takifugu rubripes ENSTRUG00000010456 9478 Tarsius syrichta ENSTSYG00000001607
9739 Tursiops truncatus ENSTTRG00000006475 30538 Vicugna pacos ENSVPAG00000007906
8083 Xiphophorus maculatus ENSXMAG00000011421