Basic Information | |||
Gene ID | 3172 ; ![]() ![]() | ||
Gene Name | HNF4A; HNF4, NR2A1, TCF14 | ||
Full Name | Hepatocyte nuclear factor 4-alpha | ||
Organism | Homo sapiens [9606] |
Cross Reference | |||
UniProt | P41235 | UniGene | Hs.116462 |
PDB | 4IQR | OMIM | 606391 |
KEGG | hsa:3172 | UCSC | uc002xma.4 |
Protein Interactions | |
DIP | DIP-499N |
IntAct | P41235 |
MINT | MINT-269829 |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
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ENSEMBL | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
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REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
NP_000448 | Gene3D | G3DSA:1.10.565.10 | IPR008946 | 145 | 377 | 3.90e-74 | Nuclear hormone receptor, ligand-binding |
NP_000448 | Gene3D | G3DSA:3.30.50.10 | IPR013088 | 57 | 139 | 4.20e-32 | Zinc finger, NHR/GATA-type |
NP_000448 | Pfam | PF00104 | IPR000536 | 177 | 361 | 1.10e-39 | Nuclear hormone receptor, ligand-binding, core |
NP_000448 | Pfam | PF00105 | IPR001628 | 59 | 127 | 8.90e-30 | Zinc finger, nuclear hormone receptor-type |
NP_000448 | PRINTS | PR00047 | IPR001628 | 109 | 117 | 2.90e-18 | Zinc finger, nuclear hormone receptor-type |
NP_000448 | PRINTS | PR00047 | IPR001628 | 117 | 125 | 2.90e-18 | Zinc finger, nuclear hormone receptor-type |
NP_000448 | PRINTS | PR00047 | IPR001628 | 60 | 76 | 2.90e-18 | Zinc finger, nuclear hormone receptor-type |
NP_000448 | PRINTS | PR00047 | IPR001628 | 76 | 91 | 2.90e-18 | Zinc finger, nuclear hormone receptor-type |
NP_000448 | PRINTS | PR00398 | IPR001723 | 121 | 131 | 1.10e-25 | Steroid hormone receptor |
NP_000448 | PRINTS | PR00398 | IPR001723 | 190 | 211 | 1.10e-25 | Steroid hormone receptor |
NP_000448 | PRINTS | PR00398 | IPR001723 | 211 | 227 | 1.10e-25 | Steroid hormone receptor |
NP_000448 | PRINTS | PR00398 | IPR001723 | 279 | 294 | 1.10e-25 | Steroid hormone receptor |
NP_000448 | PRINTS | PR00398 | IPR001723 | 336 | 353 | 1.10e-25 | Steroid hormone receptor |
NP_000448 | PRINTS | PR01282 | IPR003068 | 183 | 199 | 4.80e-07 | Transcription factor COUP |
NP_000448 | PRINTS | PR01282 | IPR003068 | 295 | 307 | 4.80e-07 | Transcription factor COUP |
NP_000448 | PRINTS | PR01282 | IPR003068 | 342 | 355 | 4.80e-07 | Transcription factor COUP |
NP_000448 | PRINTS | PR01282 | IPR003068 | 362 | 373 | 4.80e-07 | Transcription factor COUP |
NP_000448 | PRINTS | PR01282 | IPR003068 | 373 | 386 | 4.80e-07 | Transcription factor COUP |
NP_000448 | ProSitePatterns | PS00031 | IPR001628 | 60 | 86 | - | Zinc finger, nuclear hormone receptor-type |
NP_000448 | ProSiteProfiles | PS51030 | IPR001628 | 57 | 132 | 0.00e-00 | Zinc finger, nuclear hormone receptor-type |
NP_000448 | SMART | SM00399 | IPR001628 | 57 | 128 | 2.60e-40 | Zinc finger, nuclear hormone receptor-type |
NP_000448 | SMART | SM00430 | IPR000536 | 189 | 348 | 3.50e-51 | Nuclear hormone receptor, ligand-binding, core |
NP_000448 | SUPERFAMILY | SSF48508 | IPR008946 | 126 | 374 | 0.00e-00 | Nuclear hormone receptor, ligand-binding |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
NP_000448 | PF00104 | 7.69999e-40 | Hormone_recep | Ligand-binding domain of nuclear hormone receptor |
NP_000448 | PF00105 | 5.8e-30 | zf-C4 | Zinc finger, C4 type (two domains) |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
NP_000448 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
NP_000448 | GO:0003707 | molecular_function | steroid hormone receptor activity |
NP_000448 | GO:0008270 | molecular_function | zinc ion binding |
NP_000448 | GO:0043565 | molecular_function | sequence-specific DNA binding |