Basic Information
Gene ID 3234 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name HOXD8; HOX4E
Full Name Homeobox protein Hox-D8
Organism Homo sapiens [9606]

Cross Reference
UniProt P13378 UniGene Hs.700870
PDB NULL OMIM 142985
KEGG hsa:3234 UCSC uc002ukp.3

Protein Interactions
DIP NULL
IntAct P13378
MINT MINT-7032137
STRING 9606.ENSP00000315949

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000315949 Gene3D G3DSA:1.10.10.60 IPR009057 190 257 9.00e-27 Homeodomain-like
ENSP00000315949 Pfam PF00046 IPR001356 198 254 2.10e-20 Homeobox domain
ENSP00000315949 PRINTS PR00024 IPR020479 219 230 4.90e-08 Homeodomain, metazoa
ENSP00000315949 PRINTS PR00024 IPR020479 234 244 4.90e-08 Homeodomain, metazoa
ENSP00000315949 PRINTS PR00024 IPR020479 244 253 4.90e-08 Homeodomain, metazoa
ENSP00000315949 ProSitePatterns PS00027 IPR017970 230 253 - Homeobox, conserved site
ENSP00000315949 ProSitePatterns PS00032 IPR001827 185 190 - Homeobox protein, antennapedia type, conserved site
ENSP00000315949 ProSiteProfiles PS50071 IPR001356 195 255 0.00e-00 Homeobox domain
ENSP00000315949 SMART SM00389 IPR001356 197 259 5.10e-27 Homeobox domain
ENSP00000315949 SUPERFAMILY SSF46689 IPR009057 178 256 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000315949 PF00046 1.1e-20 Homeobox Homeobox domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000315949 GO:0006351 biological_process transcription, DNA-templated
ENSP00000315949 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSP00000315949 GO:0005634 cellular_component nucleus
ENSP00000315949 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10090 Mus musculus 15437 9483 Callithrix jacchus 100401383
10029 Cricetulus griseus 100758537 9555 Papio anubis 101019689
9598 Pan troglodytes 459763 9646 Ailuropoda melanoleuca ENSAMEG00000001838
9615 Canis familiaris ENSCAFG00000013450 10141 Cavia porcellus ENSCPOG00000015005
9796 Equus caballus ENSECAG00000021980 9371 Echinops telfairi ENSETEG00000011076
9595 Gorilla gorilla ENSGGOG00000009898 9785 Loxodonta africana ENSLAFG00000004364
9103 Meleagris gallopavo ENSMGAG00000017418 59463 Myotis lucifugus ENSMLUG00000028864
9544 Macaca mulatta ENSMMUG00000023504 13616 Monodelphis domestica ENSMODG00000009593
61853 Nomascus leucogenys ENSNLEG00000006003 9258 Ornithorhynchus anatinus ENSOANG00000030212
9813 Procavia capensis ENSPCAG00000015753 9601 Pongo abelii ENSPPYG00000012961
132908 Pteropus vampyrus ENSPVAG00000017420 10116 Rattus norvegicus ENSRNOG00000042480
9823 Sus scrofa ENSSSCG00000015983 43179 Ictidomys tridecemlineatus ENSSTOG00000023453
37347 Tupaia belangeri ENSTBEG00000011462 9478 Tarsius syrichta ENSTSYG00000001418
8364 Xenopus tropicalis ENSXETG00000024424 30608 Microcebus murinus ENSMICG00000004277
30611 Otolemur garnettii ENSOGAG00000015707 9978 Ochotona princeps ENSOPRG00000004065
9305 Sarcophilus harrisii ENSSHAG00000016034 9739 Tursiops truncatus ENSTTRG00000013777