Basic Information | |||
Gene ID | 367 ; ![]() ![]() | ||
Gene Name | AR; DHTR, NR3C4 | ||
Full Name | Androgen receptor | ||
Organism | Homo sapiens [9606] |
Cross Reference | |||
UniProt | P10275 | UniGene | Hs.76704 |
PDB | 4HLW | OMIM | 313700 |
KEGG | hsa:367 | UCSC | NULL |
Protein Interactions | |
DIP | DIP-125N |
IntAct | P10275 |
MINT | MINT-94801 |
STRING | 9606.ENSP00000363822 |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
ENSEMBL | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
NP_000035 | Gene3D | G3DSA:1.10.565.10 | IPR008946 | 373 | 406 | 1.60e-91 | Nuclear hormone receptor, ligand-binding |
NP_000035 | Gene3D | G3DSA:1.10.565.10 | IPR008946 | 680 | 904 | 1.60e-91 | Nuclear hormone receptor, ligand-binding |
NP_000035 | Gene3D | G3DSA:3.30.50.10 | IPR013088 | 556 | 630 | 1.10e-25 | Zinc finger, NHR/GATA-type |
NP_000035 | Pfam | PF00104 | IPR000536 | 692 | 877 | 3.10e-31 | Nuclear hormone receptor, ligand-binding, core |
NP_000035 | Pfam | PF00105 | IPR001628 | 558 | 626 | 7.50e-27 | Zinc finger, nuclear hormone receptor-type |
NP_000035 | Pfam | PF02166 | IPR001103 | 6 | 449 | 6.00e-272 | Androgen receptor |
NP_000035 | PRINTS | PR00047 | IPR001628 | 560 | 576 | 2.60e-13 | Zinc finger, nuclear hormone receptor-type |
NP_000035 | PRINTS | PR00047 | IPR001628 | 576 | 591 | 2.60e-13 | Zinc finger, nuclear hormone receptor-type |
NP_000035 | PRINTS | PR00047 | IPR001628 | 609 | 617 | 2.60e-13 | Zinc finger, nuclear hormone receptor-type |
NP_000035 | PRINTS | PR00047 | IPR001628 | 617 | 625 | 2.60e-13 | Zinc finger, nuclear hormone receptor-type |
NP_000035 | PRINTS | PR00521 | IPR001103 | 169 | 188 | 4.10e-114 | Androgen receptor |
NP_000035 | PRINTS | PR00521 | IPR001103 | 218 | 238 | 4.10e-114 | Androgen receptor |
NP_000035 | PRINTS | PR00521 | IPR001103 | 264 | 284 | 4.10e-114 | Androgen receptor |
NP_000035 | PRINTS | PR00521 | IPR001103 | 27 | 45 | 4.10e-114 | Androgen receptor |
NP_000035 | PRINTS | PR00521 | IPR001103 | 301 | 321 | 4.10e-114 | Androgen receptor |
NP_000035 | PRINTS | PR00521 | IPR001103 | 346 | 368 | 4.10e-114 | Androgen receptor |
NP_000035 | PRINTS | PR00521 | IPR001103 | 382 | 401 | 4.10e-114 | Androgen receptor |
NP_000035 | PRINTS | PR00521 | IPR001103 | 432 | 449 | 4.10e-114 | Androgen receptor |
NP_000035 | PRINTS | PR00521 | IPR001103 | 6 | 25 | 4.10e-114 | Androgen receptor |
NP_000035 | ProSitePatterns | PS00031 | IPR001628 | 560 | 586 | - | Zinc finger, nuclear hormone receptor-type |
NP_000035 | ProSiteProfiles | PS51030 | IPR001628 | 557 | 632 | 0.00e-00 | Zinc finger, nuclear hormone receptor-type |
NP_000035 | SMART | SM00399 | IPR001628 | 557 | 628 | 1.10e-34 | Zinc finger, nuclear hormone receptor-type |
NP_000035 | SMART | SM00430 | IPR000536 | 707 | 871 | 3.50e-36 | Nuclear hormone receptor, ligand-binding, core |
NP_000035 | SUPERFAMILY | SSF48508 | IPR008946 | 674 | 918 | 0.00e-00 | Nuclear hormone receptor, ligand-binding |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
NP_000035 | PF02166 | 0 | Androgen_recep | Androgen receptor |
NP_000035 | PF00104 | 3.1e-31 | Hormone_recep | Ligand-binding domain of nuclear hormone receptor |
NP_000035 | PF00105 | 3e-27 | zf-C4 | Zinc finger, C4 type (two domains) |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
NP_000035 | GO:0006351 | biological_process | transcription, DNA-templated |
NP_000035 | GO:0006355 | biological_process | regulation of transcription, DNA-templated |
NP_000035 | GO:0008284 | biological_process | positive regulation of cell proliferation |
NP_000035 | GO:0030521 | biological_process | androgen receptor signaling pathway |
NP_000035 | GO:0030522 | biological_process | intracellular receptor signaling pathway |
NP_000035 | GO:0042327 | biological_process | positive regulation of phosphorylation |
NP_000035 | GO:0043401 | biological_process | steroid hormone mediated signaling pathway |
NP_000035 | GO:0045720 | biological_process | negative regulation of integrin biosynthetic process |
NP_000035 | GO:0045893 | biological_process | positive regulation of transcription, DNA-templated |
NP_000035 | GO:0045944 | biological_process | positive regulation of transcription from RNA polymerase II promoter |
NP_000035 | GO:0051092 | biological_process | positive regulation of NF-kappaB transcription factor activity |
NP_000035 | GO:0090003 | biological_process | regulation of establishment of protein localization to plasma membrane |
NP_000035 | GO:2001237 | biological_process | negative regulation of extrinsic apoptotic signaling pathway |
NP_000035 | GO:0000790 | cellular_component | nuclear chromatin |
NP_000035 | GO:0005634 | cellular_component | nucleus |
NP_000035 | GO:0005737 | cellular_component | cytoplasm |
NP_000035 | GO:0003677 | molecular_function | DNA binding |
NP_000035 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
NP_000035 | GO:0003707 | molecular_function | steroid hormone receptor activity |
NP_000035 | GO:0004879 | molecular_function | ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity |
NP_000035 | GO:0004882 | molecular_function | androgen receptor activity |
NP_000035 | GO:0005496 | molecular_function | steroid binding |
NP_000035 | GO:0008013 | molecular_function | beta-catenin binding |
NP_000035 | GO:0008270 | molecular_function | zinc ion binding |
NP_000035 | GO:0008289 | molecular_function | lipid binding |
NP_000035 | GO:0043565 | molecular_function | sequence-specific DNA binding |
NP_000035 | GO:0044212 | molecular_function | transcription regulatory region DNA binding |
NP_000035 | GO:0046872 | molecular_function | metal ion binding |