Basic Information | |||
Gene ID | 368266 | ||
Gene Name | arhgef1; arhgef1a, si:dkey-240h12.3 | ||
Full Name | Rho guanine nucleotide exchange factor (GEF) 1 | ||
Organism | Danio rerio [7955] |
Cross Reference | |||
UniProt | A2RUX1 | UniGene | Dr.34449 |
PDB | NULL | OMIM | NULL |
KEGG | dre:368266 | UCSC | NULL |
Protein Interactions | |
DIP | NULL |
IntAct | NULL |
MINT | NULL |
STRING | 7955.ENSDARP00000059101 |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
ENSEMBL | |||
REFSEQ | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
XP_005159428 | Gene3D | G3DSA:1.20.900.10 | IPR000219 | 434 | 670 | 1.50e-46 | Dbl homology (DH) domain |
XP_005159428 | Gene3D | G3DSA:2.30.29.30 | IPR011993 | 675 | 808 | 2.60e-44 | Pleckstrin homology-like domain |
XP_005159428 | PANTHER | PTHR22825 | IPR015721 | 203 | 1047 | 0.00e-00 | Rho GTP exchange factor |
XP_005159428 | Pfam | PF00621 | IPR000219 | 459 | 650 | 1.30e-33 | Dbl homology (DH) domain |
XP_005159428 | ProSitePatterns | PS00479 | IPR002219 | 260 | 306 | - | Protein kinase C-like, phorbol ester/diacylglycerol binding |
XP_005159428 | ProSiteProfiles | PS50003 | IPR001849 | 692 | 793 | 0.00e-00 | Pleckstrin homology domain |
XP_005159428 | ProSiteProfiles | PS50010 | IPR000219 | 455 | 652 | 0.00e-00 | Dbl homology (DH) domain |
XP_005159428 | ProSiteProfiles | PS50081 | IPR002219 | 259 | 306 | 0.00e-00 | Protein kinase C-like, phorbol ester/diacylglycerol binding |
XP_005159428 | SMART | SM00109 | IPR002219 | 260 | 306 | 4.80e-10 | Protein kinase C-like, phorbol ester/diacylglycerol binding |
XP_005159428 | SMART | SM00233 | IPR001849 | 693 | 795 | 1.60e-13 | Pleckstrin homology domain |
XP_005159428 | SMART | SM00325 | IPR000219 | 459 | 651 | 7.80e-53 | Dbl homology (DH) domain |
XP_005159428 | SUPERFAMILY | SSF48065 | IPR000219 | 435 | 671 | 0.00e-00 | Dbl homology (DH) domain |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
XP_005159428 | PF00621 | 6.6e-34 | RhoGEF | RhoGEF domain |
XP_005159428 | PF00130 | 3.5e-06 | C1_1 | Phorbol esters/diacylglycerol binding domain (C1 domain) |
XP_005159428 | PF00169 | 6.4e-06 | PH | PH domain |
XP_005159428 | PF14446 | 8.9e-05 | Prok-RING_1 | Prokaryotic RING finger family 1 |
XP_005159428 | PF07649 | 0.00066 | C1_3 | C1-like domain |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
XP_005159428 | GO:0005737 | cellular_component | cytoplasm |
XP_005159428 | GO:0005089 | molecular_function | Rho guanyl-nucleotide exchange factor activity |