Basic Information
Gene ID 395247
Gene Name MADH2; SMAD2
Full Name MADH2 protein
Organism Gallus gallus [9031]

Cross Reference
UniProt Q8UWF3 UniGene Gga.44120
PDB NULL OMIM NULL
KEGG gga:395247 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 9031.ENSGALP00000038855

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSGALP00000038855 Gene3D G3DSA:2.60.200.10 IPR017855 266 467 7.90e-100 SMAD domain-like
ENSGALP00000038855 Gene3D G3DSA:3.90.520.10 IPR013019 2 183 1.20e-59 MAD homology, MH1
ENSGALP00000038855 PANTHER PTHR13703 IPR013790 1 467 0.00e-00 Dwarfin
ENSGALP00000038855 Pfam PF03165 IPR003619 41 171 2.90e-43 MAD homology 1, Dwarfin-type
ENSGALP00000038855 Pfam PF03166 IPR001132 269 444 1.50e-77 SMAD domain, Dwarfin-type
ENSGALP00000038855 ProSiteProfiles PS51075 IPR013019 10 176 0.00e-00 MAD homology, MH1
ENSGALP00000038855 ProSiteProfiles PS51076 IPR001132 274 467 0.00e-00 SMAD domain, Dwarfin-type
ENSGALP00000038855 SMART SM00523 IPR003619 36 174 1.10e-68 MAD homology 1, Dwarfin-type
ENSGALP00000038855 SMART SM00524 IPR001132 272 443 4.60e-111 SMAD domain, Dwarfin-type
ENSGALP00000038855 SUPERFAMILY SSF49879 IPR008984 217 458 0.00e-00 SMAD/FHA domain
ENSGALP00000038855 SUPERFAMILY SSF56366 IPR013019 111 171 0.00e-00 MAD homology, MH1
ENSGALP00000038855 SUPERFAMILY SSF56366 IPR013019 31 80 0.00e-00 MAD homology, MH1

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSGALP00000038855 PF03166 0 MH2 MH2 domain
ENSGALP00000038855 PF03165 1.59748e-43 MH1 MH1 domain
ENSGALP00000038855 PF10401 1.3e-06 IRF-3 Interferon-regulatory factor 3

Gene Ontology Annotation
Protein Entry Name Space Description
ENSGALP00000038855 GO:0006351 biological_process transcription, DNA-templated
ENSGALP00000038855 GO:0007179 biological_process transforming growth factor beta receptor signaling pathway
ENSGALP00000038855 GO:0005634 cellular_component nucleus
ENSGALP00000038855 GO:0005667 cellular_component transcription factor complex
ENSGALP00000038855 GO:0005737 cellular_component cytoplasm
ENSGALP00000038855 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
34638 Metaseiulus occidentalis 100906659 9597 Pan paniscus 100980706
9555 Papio anubis 101004882 9669 Mustela putorius furo 101691860
8083 Xiphophorus maculatus 102216927 13616 Monodelphis domestica 100014493
9483 Callithrix jacchus 100396826 9646 Ailuropoda melanoleuca 100467069
61853 Nomascus leucogenys 100589735 10029 Cricetulus griseus 100771578
7463 Apis florea 100864028 39432 Saimiri boliviensis 101040653
9685 Felis catus 101087179 7897 Latimeria chalumnae 102360430
59463 Myotis lucifugus 102429768 13735 Pelodiscus sinensis 102457921
28377 Anolis carolinensis ENSACAG00000009914 9913 Bos taurus ENSBTAG00000012599
9358 Choloepus hoffmanni ENSCHOG00000011289 10141 Cavia porcellus ENSCPOG00000013398
51511 Ciona savignyi ENSCSAVG00000004749 10020 Dipodomys ordii ENSDORG00000013015
9365 Erinaceus europaeus ENSEEUG00000007736 9371 Echinops telfairi ENSETEG00000003612
9595 Gorilla gorilla ENSGGOG00000004706 8049 Gadus morhua ENSGMOG00000007444
7757 Petromyzon marinus ENSPMAG00000000489 9601 Pongo abelii ENSPPYG00000009144
42254 Sorex araneus ENSSARG00000003487 9823 Sus scrofa ENSSSCG00000004505
37347 Tupaia belangeri ENSTBEG00000016121 9478 Tarsius syrichta ENSTSYG00000005303
30538 Vicugna pacos ENSVPAG00000007781 9606 Homo sapiens 4087
9615 Canis familiaris 480144 7668 Strongylocentrotus purpuratus 577345
9544 Macaca mulatta 697581 9796 Equus caballus ENSECAG00000015132
9315 Macropus eugenii ENSMEUG00000016668 9813 Procavia capensis ENSPCAG00000012688
132908 Pteropus vampyrus ENSPVAG00000007760 59729 Taeniopygia guttata ENSTGUG00000000016
9739 Tursiops truncatus ENSTTRG00000002628

Paralogs
769000