Basic Information
Gene ID 395865
Gene Name Lef-1; LEF-1, LEF1
Full Name Lymphiod enhancer binding factor 1
Organism Gallus gallus [9031]

Cross Reference
UniProt O93345 UniGene Gga.2694
PDB NULL OMIM NULL
KEGG gga:395865 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 9031.ENSGALP00000017123

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_990344 Gene3D G3DSA:1.10.30.10 IPR009071 267 349 7.20e-29 High mobility group box domain
NP_990344 Gene3D G3DSA:4.10.900.10 IPR027397 1 67 4.50e-25 Catenin binding domain
NP_990344 PANTHER PTHR10373 IPR024940 1 369 0.00e-00 Transcription factor TCF/LEF
NP_990344 PANTHER PTHR10373:SF11 IPR028769 1 369 0.00e-00 Lymphoid enhancer-binding factor 1
NP_990344 Pfam PF00505 IPR009071 269 336 1.10e-21 High mobility group box domain
NP_990344 Pfam PF08347 IPR013558 1 211 1.30e-73 CTNNB1 binding, N-teminal
NP_990344 ProSiteProfiles PS50118 IPR009071 269 337 0.00e-00 High mobility group box domain
NP_990344 SMART SM00398 IPR009071 268 338 2.50e-25 High mobility group box domain
NP_990344 SUPERFAMILY SSF47095 IPR009071 268 349 0.00e-00 High mobility group box domain

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_990344 PF08347 0 CTNNB1_binding N-terminal CTNNB1 binding
NP_990344 PF00505 1.1e-21 HMG_box HMG (high mobility group) box
NP_990344 PF09011 3.4e-08 HMG_box_2 HMG-box domain

Gene Ontology Annotation
Protein Entry Name Space Description
NP_990344 GO:0006351 biological_process transcription, DNA-templated
NP_990344 GO:0006355 biological_process regulation of transcription, DNA-templated
NP_990344 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
NP_990344 GO:0016055 biological_process Wnt signaling pathway
NP_990344 GO:0060070 biological_process canonical Wnt signaling pathway
NP_990344 GO:0005634 cellular_component nucleus
NP_990344 GO:0003677 molecular_function DNA binding
NP_990344 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
NP_990344 GO:0008013 molecular_function beta-catenin binding