Basic Information
Gene ID 4208 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name MEF2C
Full Name Myocyte-specific enhancer factor 2C
Organism Homo sapiens [9606]

Cross Reference
UniProt Q06413 UniGene Hs.649965
PDB NULL OMIM 613443
KEGG hsa:4208 UCSC uc021ybh.1

Protein Interactions
DIP DIP-40857N
IntAct Q06413
MINT MINT-125556
STRING 9606.ENSP00000396219

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_001180276 Pfam PF00319 IPR002100 10 59 4.10e-22 Transcription factor, MADS-box
NP_001180276 Pfam PF12347 IPR022102 110 173 5.90e-26 Holliday junction regulator protein family C-terminal
NP_001180276 PRINTS PR00404 IPR002100 23 38 1.30e-25 Transcription factor, MADS-box
NP_001180276 PRINTS PR00404 IPR002100 3 23 1.30e-25 Transcription factor, MADS-box
NP_001180276 PRINTS PR00404 IPR002100 38 59 1.30e-25 Transcription factor, MADS-box
NP_001180276 ProSitePatterns PS00350 IPR002100 3 57 - Transcription factor, MADS-box
NP_001180276 ProSiteProfiles PS50066 IPR002100 1 61 0.00e-00 Transcription factor, MADS-box
NP_001180276 SMART SM00432 IPR002100 1 60 8.50e-40 Transcription factor, MADS-box
NP_001180276 SUPERFAMILY SSF55455 IPR002100 2 89 0.00e-00 Transcription factor, MADS-box

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_001180276 PF12347 2.7e-26 HJURP_C Holliday junction regulator protein family C-terminal repeat
NP_001180276 PF00319 2.4e-22 SRF-TF SRF-type transcription factor (DNA-binding and dimerisation domain)

Gene Ontology Annotation
Protein Entry Name Space Description
NP_001180276 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
NP_001180276 GO:0000165 biological_process MAPK cascade
NP_001180276 GO:0006366 biological_process transcription from RNA polymerase II promoter
NP_001180276 GO:0006915 biological_process apoptotic process
NP_001180276 GO:0007507 biological_process heart development
NP_001180276 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
NP_001180276 GO:0071277 biological_process cellular response to calcium ion
NP_001180276 GO:0005634 cellular_component nucleus
NP_001180276 GO:0005737 cellular_component cytoplasm
NP_001180276 GO:0000977 molecular_function RNA polymerase II regulatory region sequence-specific DNA binding
NP_001180276 GO:0000981 molecular_function sequence-specific DNA binding RNA polymerase II transcription factor activity
NP_001180276 GO:0001077 molecular_function RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
NP_001180276 GO:0003677 molecular_function DNA binding
NP_001180276 GO:0003682 molecular_function chromatin binding
NP_001180276 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
NP_001180276 GO:0033613 molecular_function activating transcription factor binding
NP_001180276 GO:0042826 molecular_function histone deacetylase binding
NP_001180276 GO:0046983 molecular_function protein dimerization activity