Basic Information | |||
Gene ID | 459204 | ||
Gene Name | EPAS1 | ||
Full Name | Endothelial PAS domain protein 1 | ||
Organism | Pan troglodytes [9598] |
Cross Reference | |||
UniProt | H2QHV1 | UniGene | NULL |
PDB | NULL | OMIM | NULL |
KEGG | ptr:459204 | UCSC | NULL |
Protein Interactions | |
DIP | NULL |
IntAct | NULL |
MINT | NULL |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
XP_001147219 | Pfam | PF00989 | IPR013767 | 93 | 163 | 4.80e-05 | PAS fold |
XP_001147219 | Pfam | PF08778 | IPR014887 | 831 | 870 | 3.30e-20 | HIF-1 alpha, transactivation domain, C-terminal |
XP_001147219 | Pfam | PF11413 | IPR021537 | 517 | 549 | 9.40e-18 | Hypoxia-inducible factor, alpha subunit |
XP_001147219 | PRINTS | PR00785 | IPR001067 | 101 | 120 | 9.20e-07 | Nuclear translocator |
XP_001147219 | PRINTS | PR00785 | IPR001067 | 243 | 260 | 9.20e-07 | Nuclear translocator |
XP_001147219 | PRINTS | PR00785 | IPR001067 | 49 | 69 | 9.20e-07 | Nuclear translocator |
XP_001147219 | ProSiteProfiles | PS50112 | IPR000014 | 249 | 300 | 0.00e-00 | PAS domain |
XP_001147219 | ProSiteProfiles | PS50112 | IPR000014 | 92 | 147 | 0.00e-00 | PAS domain |
XP_001147219 | ProSiteProfiles | PS50888 | IPR011598 | 14 | 67 | 0.00e-00 | Myc-type, basic helix-loop-helix (bHLH) domain |
XP_001147219 | SMART | SM00086 | IPR001610 | 304 | 347 | 2.20e-11 | PAC motif |
XP_001147219 | SMART | SM00091 | IPR000014 | 232 | 298 | 3.70e-10 | PAS domain |
XP_001147219 | SMART | SM00091 | IPR000014 | 86 | 152 | 1.50e-11 | PAS domain |
XP_001147219 | SMART | SM00353 | IPR011598 | 20 | 75 | 1.30e-11 | Myc-type, basic helix-loop-helix (bHLH) domain |
XP_001147219 | SUPERFAMILY | SSF47459 | IPR011598 | 11 | 72 | 0.00e-00 | Myc-type, basic helix-loop-helix (bHLH) domain |
XP_001147219 | SUPERFAMILY | SSF55785 | IPR000014 | 244 | 346 | 0.00e-00 | PAS domain |
XP_001147219 | SUPERFAMILY | SSF55785 | IPR000014 | 95 | 201 | 0.00e-00 | PAS domain |
XP_001147219 | TIGRFAM | TIGR00229 | IPR000014 | 252 | 328 | 4.70e-08 | PAS domain |
XP_001147219 | TIGRFAM | TIGR00229 | IPR000014 | 98 | 150 | 1.00e-05 | PAS domain |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
XP_001147219 | PF14598 | 2.2e-28 | PAS_11 | PAS domain |
XP_001147219 | PF08447 | 4.6e-25 | PAS_3 | PAS fold |
XP_001147219 | PF08778 | 1.6e-20 | HIF-1a_CTAD | HIF-1 alpha C terminal transactivation domain |
XP_001147219 | PF11413 | 4.4e-18 | HIF-1 | Hypoxia-inducible factor-1 |
XP_001147219 | PF00989 | 1.4e-14 | PAS | PAS fold |
XP_001147219 | PF13426 | 8.8e-11 | PAS_9 | PAS domain |
XP_001147219 | PF08448 | 1.5e-07 | PAS_4 | PAS fold |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
XP_001147219 | GO:0001666 | biological_process | response to hypoxia |
XP_001147219 | GO:0045893 | biological_process | positive regulation of transcription, DNA-templated |
XP_001147219 | GO:0045944 | biological_process | positive regulation of transcription from RNA polymerase II promoter |
XP_001147219 | GO:0071456 | biological_process | cellular response to hypoxia |
XP_001147219 | GO:0005634 | cellular_component | nucleus |
XP_001147219 | GO:0005737 | cellular_component | cytoplasm |
XP_001147219 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
XP_001147219 | GO:0004871 | molecular_function | signal transducer activity |
XP_001147219 | GO:0035035 | molecular_function | histone acetyltransferase binding |