Basic Information
Gene ID 459204
Gene Name EPAS1
Full Name Endothelial PAS domain protein 1
Organism Pan troglodytes [9598]

Cross Reference
UniProt H2QHV1 UniGene NULL
PDB NULL OMIM NULL
KEGG ptr:459204 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
XP_001147219 Pfam PF00989 IPR013767 93 163 4.80e-05 PAS fold
XP_001147219 Pfam PF08778 IPR014887 831 870 3.30e-20 HIF-1 alpha, transactivation domain, C-terminal
XP_001147219 Pfam PF11413 IPR021537 517 549 9.40e-18 Hypoxia-inducible factor, alpha subunit
XP_001147219 PRINTS PR00785 IPR001067 101 120 9.20e-07 Nuclear translocator
XP_001147219 PRINTS PR00785 IPR001067 243 260 9.20e-07 Nuclear translocator
XP_001147219 PRINTS PR00785 IPR001067 49 69 9.20e-07 Nuclear translocator
XP_001147219 ProSiteProfiles PS50112 IPR000014 249 300 0.00e-00 PAS domain
XP_001147219 ProSiteProfiles PS50112 IPR000014 92 147 0.00e-00 PAS domain
XP_001147219 ProSiteProfiles PS50888 IPR011598 14 67 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
XP_001147219 SMART SM00086 IPR001610 304 347 2.20e-11 PAC motif
XP_001147219 SMART SM00091 IPR000014 232 298 3.70e-10 PAS domain
XP_001147219 SMART SM00091 IPR000014 86 152 1.50e-11 PAS domain
XP_001147219 SMART SM00353 IPR011598 20 75 1.30e-11 Myc-type, basic helix-loop-helix (bHLH) domain
XP_001147219 SUPERFAMILY SSF47459 IPR011598 11 72 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
XP_001147219 SUPERFAMILY SSF55785 IPR000014 244 346 0.00e-00 PAS domain
XP_001147219 SUPERFAMILY SSF55785 IPR000014 95 201 0.00e-00 PAS domain
XP_001147219 TIGRFAM TIGR00229 IPR000014 252 328 4.70e-08 PAS domain
XP_001147219 TIGRFAM TIGR00229 IPR000014 98 150 1.00e-05 PAS domain

Pfam Annotation
Protein Pfam ID E.value Name Description
XP_001147219 PF14598 2.2e-28 PAS_11 PAS domain
XP_001147219 PF08447 4.6e-25 PAS_3 PAS fold
XP_001147219 PF08778 1.6e-20 HIF-1a_CTAD HIF-1 alpha C terminal transactivation domain
XP_001147219 PF11413 4.4e-18 HIF-1 Hypoxia-inducible factor-1
XP_001147219 PF00989 1.4e-14 PAS PAS fold
XP_001147219 PF13426 8.8e-11 PAS_9 PAS domain
XP_001147219 PF08448 1.5e-07 PAS_4 PAS fold

Gene Ontology Annotation
Protein Entry Name Space Description
XP_001147219 GO:0001666 biological_process response to hypoxia
XP_001147219 GO:0045893 biological_process positive regulation of transcription, DNA-templated
XP_001147219 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
XP_001147219 GO:0071456 biological_process cellular response to hypoxia
XP_001147219 GO:0005634 cellular_component nucleus
XP_001147219 GO:0005737 cellular_component cytoplasm
XP_001147219 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
XP_001147219 GO:0004871 molecular_function signal transducer activity
XP_001147219 GO:0035035 molecular_function histone acetyltransferase binding