Basic Information
Gene ID 488449
Gene Name STAT1
Full Name Signal transducer and activator of transcription
Organism Canis familiaris [9615]

Cross Reference
UniProt E2RI99 UniGene NULL
PDB NULL OMIM NULL
KEGG cfa:488449 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
XP_848353 Gene3D G3DSA:1.10.238.10 IPR011992 461 581 1.40e-50 EF-hand domain pair
XP_848353 Gene3D G3DSA:1.10.532.10 IPR013799 1 121 1.30e-46 STAT transcription factor, protein interaction
XP_848353 Gene3D G3DSA:1.20.1050.20 IPR013800 137 317 2.60e-68 STAT transcription factor, all-alpha
XP_848353 Gene3D G3DSA:2.60.40.630 IPR012345 318 460 1.10e-65 STAT transcription factor, DNA-binding, subdomain
XP_848353 Gene3D G3DSA:3.30.505.10 IPR000980 582 711 3.30e-51 SH2 domain
XP_848353 PANTHER PTHR11801 IPR001217 2 747 0.00e-00 Transcription factor STAT
XP_848353 Pfam PF00017 IPR000980 579 639 2.20e-08 SH2 domain
XP_848353 Pfam PF01017 IPR013800 137 315 1.40e-64 STAT transcription factor, all-alpha
XP_848353 Pfam PF02864 IPR013801 317 567 1.20e-119 STAT transcription factor, DNA-binding
XP_848353 Pfam PF02865 IPR013799 2 121 5.80e-43 STAT transcription factor, protein interaction
XP_848353 Pfam PF12162 IPR022752 715 739 4.20e-12 Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal
XP_848353 ProSiteProfiles PS50001 IPR000980 573 670 0.00e-00 SH2 domain
XP_848353 SMART SM00252 IPR000980 571 687 2.60e-03 SH2 domain
XP_848353 SMART SM00964 IPR013799 2 122 1.90e-66 STAT transcription factor, protein interaction
XP_848353 SUPERFAMILY SSF47655 IPR015988 134 317 0.00e-00 STAT transcription factor, coiled coil
XP_848353 SUPERFAMILY SSF48092 IPR013799 1 121 0.00e-00 STAT transcription factor, protein interaction
XP_848353 SUPERFAMILY SSF49417 IPR008967 317 568 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
XP_848353 PF01017 0 STAT_alpha STAT protein, all-alpha domain
XP_848353 PF02864 0 STAT_bind STAT protein, DNA binding domain
XP_848353 PF02865 5.80138e-43 STAT_int STAT protein, protein interaction domain
XP_848353 PF12162 1.7e-12 STAT1_TAZ2bind STAT1 TAZ2 binding domain
XP_848353 PF00017 3.1e-09 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
XP_848353 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
XP_848353 GO:0045893 biological_process positive regulation of transcription, DNA-templated
XP_848353 GO:0060397 biological_process JAK-STAT cascade involved in growth hormone signaling pathway
XP_848353 GO:0005634 cellular_component nucleus
XP_848353 GO:0005737 cellular_component cytoplasm
XP_848353 GO:0003677 molecular_function DNA binding
XP_848353 GO:0004871 molecular_function signal transducer activity
XP_848353 GO:0005509 molecular_function calcium ion binding
XP_848353 GO:0019901 molecular_function protein kinase binding