Basic Information
Gene ID 489614
Gene Name HES5
Full Name Uncharacterized protein
Organism Canis familiaris [9615]

Cross Reference
UniProt E2QXY9 UniGene NULL
PDB NULL OMIM NULL
KEGG cfa:489614 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSCAFP00000028708 Gene3D G3DSA:4.10.280.10 IPR011598 18 71 5.50e-14 Myc-type, basic helix-loop-helix (bHLH) domain
ENSCAFP00000028708 Pfam PF00010 IPR011598 18 71 1.90e-15 Myc-type, basic helix-loop-helix (bHLH) domain
ENSCAFP00000028708 Pfam PF07527 IPR003650 86 122 8.00e-08 Orange
ENSCAFP00000028708 ProSiteProfiles PS50888 IPR011598 16 72 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSCAFP00000028708 ProSiteProfiles PS51054 IPR003650 88 119 0.00e-00 Orange
ENSCAFP00000028708 SMART SM00353 IPR011598 22 78 1.60e-14 Myc-type, basic helix-loop-helix (bHLH) domain
ENSCAFP00000028708 SMART SM00511 IPR018352 86 128 2.50e-11 Orange subgroup
ENSCAFP00000028708 SUPERFAMILY SSF47459 IPR011598 17 72 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSCAFP00000028708 PF00010 1.1e-15 HLH Helix-loop-helix DNA-binding domain
ENSCAFP00000028708 PF07527 5e-08 Hairy_orange Hairy Orange

Gene Ontology Annotation
Protein Entry Name Space Description
ENSCAFP00000028708 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
ENSCAFP00000028708 GO:0006351 biological_process transcription, DNA-templated
ENSCAFP00000028708 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSCAFP00000028708 GO:0007219 biological_process Notch signaling pathway
ENSCAFP00000028708 GO:0045892 biological_process negative regulation of transcription, DNA-templated
ENSCAFP00000028708 GO:0005634 cellular_component nucleus
ENSCAFP00000028708 GO:0003677 molecular_function DNA binding
ENSCAFP00000028708 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
13616 Monodelphis domestica 100027928 8128 Oreochromis niloticus 100692255
10141 Cavia porcellus 100725154 9305 Sarcophilus harrisii 100933566
9555 Papio anubis 101024013 39432 Saimiri boliviensis 101029841
31033 Takifugu rubripes 101076256 9595 Gorilla gorilla 101133321
8083 Xiphophorus maculatus 102218095 7897 Latimeria chalumnae 102346203
13735 Pelodiscus sinensis 102454467 10090 Mus musculus 15208
9606 Homo sapiens 388585 7955 Danio rerio 402914
9365 Erinaceus europaeus ENSEEUG00000008377 8049 Gadus morhua ENSGMOG00000014868
9103 Meleagris gallopavo ENSMGAG00000002009 9813 Procavia capensis ENSPCAG00000001025
59729 Taeniopygia guttata ENSTGUG00000016560 8364 Xenopus tropicalis ENSXETG00000011110
28377 Anolis carolinensis ENSACAG00000003188 9646 Ailuropoda melanoleuca ENSAMEG00000013176
9371 Echinops telfairi ENSETEG00000005870 9685 Felis catus ENSFCAG00000023238
69293 Gasterosteus aculeatus ENSGACG00000006359 9031 Gallus gallus ENSGALG00000001136
9785 Loxodonta africana ENSLAFG00000005276 9315 Macropus eugenii ENSMEUG00000013913
9544 Macaca mulatta ENSMMUG00000014688 8090 Oryzias latipes ENSORLG00000003974
132908 Pteropus vampyrus ENSPVAG00000002198 43179 Ictidomys tridecemlineatus ENSSTOG00000020897
99883 Tetraodon nigroviridis ENSTNIG00000011996 9739 Tursiops truncatus ENSTTRG00000003782