Basic Information | |||
Gene ID | 5465 ; ![]() ![]() | ||
Gene Name | PPARA; NR1C1, PPAR | ||
Full Name | Peroxisome proliferator-activated receptor alpha | ||
Organism | Homo sapiens [9606] |
Cross Reference | |||
UniProt | Q07869 | UniGene | Hs.710044 |
PDB | 4BCR | OMIM | 170998 |
KEGG | hsa:5465 | UCSC | uc003bgw.1 |
Protein Interactions | |
DIP | DIP-241N |
IntAct | Q07869 |
MINT | MINT-232229 |
STRING | 9606.ENSP00000262735 |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
NP_001001928 | Gene3D | G3DSA:1.10.565.10 | IPR008946 | 155 | 185 | 4.80e-71 | Nuclear hormone receptor, ligand-binding |
NP_001001928 | Gene3D | G3DSA:1.10.565.10 | IPR008946 | 242 | 465 | 4.80e-71 | Nuclear hormone receptor, ligand-binding |
NP_001001928 | Gene3D | G3DSA:3.30.50.10 | IPR013088 | 102 | 154 | 5.90e-25 | Zinc finger, NHR/GATA-type |
NP_001001928 | Pfam | PF00104 | IPR000536 | 278 | 446 | 9.20e-25 | Nuclear hormone receptor, ligand-binding, core |
NP_001001928 | Pfam | PF00105 | IPR001628 | 101 | 167 | 5.40e-28 | Zinc finger, nuclear hormone receptor-type |
NP_001001928 | PRINTS | PR00047 | IPR001628 | 102 | 118 | 8.00e-19 | Zinc finger, nuclear hormone receptor-type |
NP_001001928 | PRINTS | PR00047 | IPR001628 | 118 | 133 | 8.00e-19 | Zinc finger, nuclear hormone receptor-type |
NP_001001928 | PRINTS | PR00047 | IPR001628 | 150 | 158 | 8.00e-19 | Zinc finger, nuclear hormone receptor-type |
NP_001001928 | PRINTS | PR00047 | IPR001628 | 158 | 166 | 8.00e-19 | Zinc finger, nuclear hormone receptor-type |
NP_001001928 | PRINTS | PR00398 | IPR001723 | 162 | 172 | 7.80e-26 | Steroid hormone receptor |
NP_001001928 | PRINTS | PR00398 | IPR001723 | 279 | 300 | 7.80e-26 | Steroid hormone receptor |
NP_001001928 | PRINTS | PR00398 | IPR001723 | 300 | 316 | 7.80e-26 | Steroid hormone receptor |
NP_001001928 | PRINTS | PR00398 | IPR001723 | 368 | 383 | 7.80e-26 | Steroid hormone receptor |
NP_001001928 | PRINTS | PR00398 | IPR001723 | 425 | 442 | 7.80e-26 | Steroid hormone receptor |
NP_001001928 | PRINTS | PR01288 | IPR003074 | 192 | 206 | 1.70e-53 | Peroxisome proliferator-activated receptor |
NP_001001928 | PRINTS | PR01288 | IPR003074 | 206 | 225 | 1.70e-53 | Peroxisome proliferator-activated receptor |
NP_001001928 | PRINTS | PR01288 | IPR003074 | 318 | 331 | 1.70e-53 | Peroxisome proliferator-activated receptor |
NP_001001928 | PRINTS | PR01288 | IPR003074 | 335 | 350 | 1.70e-53 | Peroxisome proliferator-activated receptor |
NP_001001928 | PRINTS | PR01288 | IPR003074 | 353 | 366 | 1.70e-53 | Peroxisome proliferator-activated receptor |
NP_001001928 | PRINTS | PR01288 | IPR003074 | 415 | 432 | 1.70e-53 | Peroxisome proliferator-activated receptor |
NP_001001928 | PRINTS | PR01288 | IPR003074 | 449 | 461 | 1.70e-53 | Peroxisome proliferator-activated receptor |
NP_001001928 | PRINTS | PR01289 | IPR003076 | 245 | 262 | 1.60e-71 | Peroxisome proliferator-activated receptor, alpha |
NP_001001928 | PRINTS | PR01289 | IPR003076 | 28 | 49 | 1.60e-71 | Peroxisome proliferator-activated receptor, alpha |
NP_001001928 | PRINTS | PR01289 | IPR003076 | 397 | 414 | 1.60e-71 | Peroxisome proliferator-activated receptor, alpha |
NP_001001928 | PRINTS | PR01289 | IPR003076 | 49 | 70 | 1.60e-71 | Peroxisome proliferator-activated receptor, alpha |
NP_001001928 | PRINTS | PR01289 | IPR003076 | 72 | 89 | 1.60e-71 | Peroxisome proliferator-activated receptor, alpha |
NP_001001928 | PRINTS | PR01289 | IPR003076 | 9 | 27 | 1.60e-71 | Peroxisome proliferator-activated receptor, alpha |
NP_001001928 | ProSitePatterns | PS00031 | IPR001628 | 102 | 128 | - | Zinc finger, nuclear hormone receptor-type |
NP_001001928 | ProSiteProfiles | PS51030 | IPR001628 | 99 | 173 | 0.00e-00 | Zinc finger, nuclear hormone receptor-type |
NP_001001928 | SMART | SM00399 | IPR001628 | 99 | 169 | 7.40e-37 | Zinc finger, nuclear hormone receptor-type |
NP_001001928 | SMART | SM00430 | IPR000536 | 278 | 437 | 3.80e-28 | Nuclear hormone receptor, ligand-binding, core |
NP_001001928 | SUPERFAMILY | SSF48508 | IPR008946 | 204 | 467 | 0.00e-00 | Nuclear hormone receptor, ligand-binding |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
NP_001001928 | PF00105 | 2.7e-28 | zf-C4 | Zinc finger, C4 type (two domains) |
NP_001001928 | PF00104 | 5e-25 | Hormone_recep | Ligand-binding domain of nuclear hormone receptor |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
NP_001001928 | GO:0000122 | biological_process | negative regulation of transcription from RNA polymerase II promoter |
NP_001001928 | GO:0030522 | biological_process | intracellular receptor signaling pathway |
NP_001001928 | GO:0042060 | biological_process | wound healing |
NP_001001928 | GO:0045893 | biological_process | positive regulation of transcription, DNA-templated |
NP_001001928 | GO:0005634 | cellular_component | nucleus |
NP_001001928 | GO:0003677 | molecular_function | DNA binding |
NP_001001928 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
NP_001001928 | GO:0003707 | molecular_function | steroid hormone receptor activity |
NP_001001928 | GO:0004879 | molecular_function | ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity |
NP_001001928 | GO:0008144 | molecular_function | drug binding |
NP_001001928 | GO:0008270 | molecular_function | zinc ion binding |
NP_001001928 | GO:0008289 | molecular_function | lipid binding |
NP_001001928 | GO:0043565 | molecular_function | sequence-specific DNA binding |