Basic Information
Gene ID 554561
Gene Name traf6; si:dkey-56p7.3, zgc:63704
Full Name TNF receptor-associated factor 6
Organism Danio rerio [7955]

Cross Reference
UniProt Q6IWL4 UniGene Dr.74618
PDB NULL OMIM NULL
KEGG dre:554561 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 7955.ENSDARP00000036715

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_001038217 Gene3D G3DSA:3.30.40.10 IPR013083 62 141 9.90e-17 Zinc finger, RING/FYVE/PHD-type
NP_001038217 Gene3D G3DSA:3.90.890.10 IPR013323 142 178 3.80e-06 SIAH-type domain
NP_001038217 PANTHER PTHR10131:SF48 IPR027139 1 542 0.00e-00 TNF receptor-associated factor 6
NP_001038217 Pfam PF00917 IPR002083 382 520 9.10e-19 MATH
NP_001038217 PIRSF PIRSF015614 IPR012227 10 528 1.20e-263 TNF receptor-associated factor TRAF
NP_001038217 ProSitePatterns PS00518 IPR017907 86 95 - Zinc finger, RING-type, conserved site
NP_001038217 ProSiteProfiles PS50089 IPR001841 71 110 0.00e-00 Zinc finger, RING-type
NP_001038217 ProSiteProfiles PS50144 IPR002083 374 520 0.00e-00 MATH
NP_001038217 ProSiteProfiles PS50145 IPR001293 205 259 0.00e-00 Zinc finger, TRAF-type
NP_001038217 SMART SM00061 IPR002083 379 503 2.40e-10 MATH
NP_001038217 SMART SM00184 IPR001841 71 109 8.90e-12 Zinc finger, RING-type
NP_001038217 SUPERFAMILY SSF49599 IPR008974 130 199 0.00e-00 TRAF-like
NP_001038217 SUPERFAMILY SSF49599 IPR008974 193 270 0.00e-00 TRAF-like
NP_001038217 SUPERFAMILY SSF49599 IPR008974 372 521 0.00e-00 TRAF-like

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_001038217 PF00917 1.5e-19 MATH MATH domain
NP_001038217 PF02176 2.9e-14 zf-TRAF TRAF-type zinc finger
NP_001038217 PF13923 3e-10 zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger)
NP_001038217 PF13639 6.8e-10 zf-RING_2 Ring finger domain
NP_001038217 PF00097 9e-09 zf-C3HC4 Zinc finger, C3HC4 type (RING finger)
NP_001038217 PF13920 1.6e-07 zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger)
NP_001038217 PF14634 4.5e-06 zf-RING_5 zinc-RING finger domain
NP_001038217 PF15227 9e-06 zf-C3HC4_4 zinc finger of C3HC4-type, RING
NP_001038217 PF00751 0.0006 DM DM DNA binding domain

Gene Ontology Annotation
Protein Entry Name Space Description
NP_001038217 GO:0000209 biological_process protein polyubiquitination
NP_001038217 GO:0001503 biological_process ossification
NP_001038217 GO:0007250 biological_process activation of NF-kappaB-inducing kinase activity
NP_001038217 GO:0031666 biological_process positive regulation of lipopolysaccharide-mediated signaling pathway
NP_001038217 GO:0042981 biological_process regulation of apoptotic process
NP_001038217 GO:0043123 biological_process positive regulation of I-kappaB kinase/NF-kappaB signaling
NP_001038217 GO:0043507 biological_process positive regulation of JUN kinase activity
NP_001038217 GO:0045672 biological_process positive regulation of osteoclast differentiation
NP_001038217 GO:0048468 biological_process cell development
NP_001038217 GO:0050852 biological_process T cell receptor signaling pathway
NP_001038217 GO:0051092 biological_process positive regulation of NF-kappaB transcription factor activity
NP_001038217 GO:0051865 biological_process protein autoubiquitination
NP_001038217 GO:0070498 biological_process interleukin-1-mediated signaling pathway
NP_001038217 GO:0070534 biological_process protein K63-linked ubiquitination
NP_001038217 GO:0005737 cellular_component cytoplasm
NP_001038217 GO:0005811 cellular_component lipid particle
NP_001038217 GO:0005938 cellular_component cell cortex
NP_001038217 GO:0004842 molecular_function ubiquitin-protein ligase activity
NP_001038217 GO:0004871 molecular_function signal transducer activity
NP_001038217 GO:0008270 molecular_function zinc ion binding