Basic Information | |||
Gene ID | 57801 ; Check Expression Profles ; Check TFs & Targets Binding | ||
Gene Name | HES4; BHLHB42 | ||
Full Name | Transcription factor HES-4 | ||
Organism | Homo sapiens [9606] |
Cross Reference | |||
UniProt | Q9HCC6 | UniGene | Hs.154029 |
PDB | NULL | OMIM | 608060 |
KEGG | hsa:57801 | UCSC | uc001aci.2 |
Protein Interactions | |
DIP | NULL |
IntAct | Q9HCC6 |
MINT | NULL |
STRING | 9606.ENSP00000393198 |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSP00000393198 | Gene3D | G3DSA:4.10.280.10 | IPR011598 | 63 | 119 | 2.10e-13 | Myc-type, basic helix-loop-helix (bHLH) domain |
ENSP00000393198 | Pfam | PF00010 | IPR011598 | 64 | 117 | 1.20e-13 | Myc-type, basic helix-loop-helix (bHLH) domain |
ENSP00000393198 | Pfam | PF07527 | IPR003650 | 135 | 175 | 1.00e-16 | Orange |
ENSP00000393198 | ProSiteProfiles | PS50888 | IPR011598 | 60 | 117 | 0.00e-00 | Myc-type, basic helix-loop-helix (bHLH) domain |
ENSP00000393198 | ProSiteProfiles | PS51054 | IPR003650 | 136 | 169 | 0.00e-00 | Orange |
ENSP00000393198 | SMART | SM00353 | IPR011598 | 66 | 123 | 9.70e-15 | Myc-type, basic helix-loop-helix (bHLH) domain |
ENSP00000393198 | SMART | SM00511 | IPR018352 | 134 | 178 | 6.10e-15 | Orange subgroup |
ENSP00000393198 | SUPERFAMILY | SSF47459 | IPR011598 | 55 | 120 | 0.00e-00 | Myc-type, basic helix-loop-helix (bHLH) domain |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSP00000393198 | PF07527 | 4.8e-17 | Hairy_orange | Hairy Orange |
ENSP00000393198 | PF00010 | 6.5e-14 | HLH | Helix-loop-helix DNA-binding domain |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
ENSP00000393198 | GO:0000122 | biological_process | negative regulation of transcription from RNA polymerase II promoter |
ENSP00000393198 | GO:0006351 | biological_process | transcription, DNA-templated |
ENSP00000393198 | GO:0006355 | biological_process | regulation of transcription, DNA-templated |
ENSP00000393198 | GO:0007219 | biological_process | Notch signaling pathway |
ENSP00000393198 | GO:0007275 | biological_process | multicellular organismal development |
ENSP00000393198 | GO:0045892 | biological_process | negative regulation of transcription, DNA-templated |
ENSP00000393198 | GO:0005634 | cellular_component | nucleus |
ENSP00000393198 | GO:0003677 | molecular_function | DNA binding |
ENSP00000393198 | GO:0043565 | molecular_function | sequence-specific DNA binding |
ENSP00000393198 | GO:0046982 | molecular_function | protein heterodimerization activity |
ENSP00000393198 | GO:0046983 | molecular_function | protein dimerization activity |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
9555 | Papio anubis | 101022336 | 9669 | Mustela putorius furo | 101685413 |
43179 | Ictidomys tridecemlineatus | 101957580 | 9598 | Pan troglodytes | 741139 |
9646 | Ailuropoda melanoleuca | ENSAMEG00000016570 | 9371 | Echinops telfairi | ENSETEG00000019989 |
9595 | Gorilla gorilla | ENSGGOG00000013399 | 30608 | Microcebus murinus | ENSMICG00000015660 |
132908 | Pteropus vampyrus | ENSPVAG00000010837 | 9361 | Dasypus novemcinctus | ENSDNOG00000024495 |