Basic Information
Gene ID 6015 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name RING1; RNF1
Full Name E3 ubiquitin-protein ligase RING1
Organism Homo sapiens [9606]

Cross Reference
UniProt Q06587 UniGene Hs.631989
PDB NULL OMIM 602045
KEGG hsa:6015 UCSC uc003odk.3

Protein Interactions
DIP DIP-42043N
IntAct Q06587
MINT MINT-1327105
STRING 9606.ENSP00000363787

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000400572 Gene3D G3DSA:3.30.40.10 IPR013083 30 124 1.00e-23 Zinc finger, RING/FYVE/PHD-type
ENSP00000400572 Pfam PF00097 IPR018957 48 87 2.10e-10 Zinc finger, C3HC4 RING-type
ENSP00000400572 ProSitePatterns PS00518 IPR017907 64 73 - Zinc finger, RING-type, conserved site
ENSP00000400572 ProSiteProfiles PS50089 IPR001841 48 88 0.00e-00 Zinc finger, RING-type
ENSP00000400572 SMART SM00184 IPR001841 48 87 3.10e-10 Zinc finger, RING-type

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000400572 PF00097 1.2e-10 zf-C3HC4 Zinc finger, C3HC4 type (RING finger)
ENSP00000400572 PF13639 8.6e-09 zf-RING_2 Ring finger domain
ENSP00000400572 PF13923 4.6e-08 zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger)
ENSP00000400572 PF13920 2.1e-06 zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger)
ENSP00000400572 PF14634 2.3e-05 zf-RING_5 zinc-RING finger domain
ENSP00000400572 PF15227 5.8e-05 zf-C3HC4_4 zinc finger of C3HC4-type, RING
ENSP00000400572 PF11789 6.4e-05 zf-Nse Zinc-finger of the MIZ type in Nse subunit
ENSP00000400572 PF14570 0.00042 zf-RING_4 RING/Ubox like zinc-binding domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000400572 GO:0006351 biological_process transcription, DNA-templated
ENSP00000400572 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSP00000400572 GO:0016567 biological_process protein ubiquitination
ENSP00000400572 GO:0016568 biological_process chromatin modification
ENSP00000400572 GO:0005634 cellular_component nucleus
ENSP00000400572 GO:0016607 cellular_component nuclear speck
ENSP00000400572 GO:0031519 cellular_component PcG protein complex
ENSP00000400572 GO:0035102 cellular_component PRC1 complex
ENSP00000400572 GO:0008270 molecular_function zinc ion binding
ENSP00000400572 GO:0016874 molecular_function ligase activity
ENSP00000400572 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9555 Papio anubis 101021344 9669 Mustela putorius furo 101680846
9598 Pan troglodytes 462604 9796 Equus caballus 100061452
9823 Sus scrofa 100153162 9601 Pongo abelii 100461906
9646 Ailuropoda melanoleuca 100475201 9597 Pan paniscus 100993986
39432 Saimiri boliviensis 101041698 9685 Felis catus 101086561
9595 Gorilla gorilla 101143477 43179 Ictidomys tridecemlineatus 101956713
10116 Rattus norvegicus 309626 9913 Bos taurus ENSBTAG00000018884
10020 Dipodomys ordii ENSDORG00000013820 9371 Echinops telfairi ENSETEG00000012485
9785 Loxodonta africana ENSLAFG00000027098 59463 Myotis lucifugus ENSMLUG00000024412
13616 Monodelphis domestica ENSMODG00000014169 9258 Ornithorhynchus anatinus ENSOANG00000006328
9978 Ochotona princeps ENSOPRG00000000924 9813 Procavia capensis ENSPCAG00000010684
132908 Pteropus vampyrus ENSPVAG00000001896 9305 Sarcophilus harrisii ENSSHAG00000006288
9739 Tursiops truncatus ENSTTRG00000004296 9361 Dasypus novemcinctus ENSDNOG00000019606
9315 Macropus eugenii ENSMEUG00000008676 9544 Macaca mulatta ENSMMUG00000003863