Basic Information
Gene ID 604 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name BCL6; BCL5, LAZ3, ZBTB27, ZNF51
Full Name B-cell lymphoma 6 protein
Organism Homo sapiens [9606]

Cross Reference
UniProt P41182 UniGene Hs.478588
PDB 3LBZ OMIM 109565
KEGG hsa:604 UCSC uc011bsf.1

Protein Interactions
DIP DIP-2651N
IntAct P41182
MINT MINT-158757
STRING 9606.ENSP00000232014

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000384371 Gene3D G3DSA:3.30.160.60 IPR013087 544 575 4.20e-14 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000384371 Gene3D G3DSA:3.30.160.60 IPR013087 576 595 3.00e-15 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000384371 Gene3D G3DSA:3.30.160.60 IPR013087 596 621 7.30e-15 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000384371 Gene3D G3DSA:3.30.160.60 IPR013087 622 649 7.30e-16 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000384371 Gene3D G3DSA:3.30.160.60 IPR013087 650 679 5.60e-10 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000384371 Gene3D G3DSA:3.30.710.10 IPR011333 8 127 1.60e-32 BTB/POZ fold
ENSP00000384371 Pfam PF00651 IPR013069 22 128 2.40e-27 BTB/POZ
ENSP00000384371 ProSitePatterns PS00028 IPR007087 520 541 - Zinc finger, C2H2
ENSP00000384371 ProSitePatterns PS00028 IPR007087 548 568 - Zinc finger, C2H2
ENSP00000384371 ProSitePatterns PS00028 IPR007087 576 596 - Zinc finger, C2H2
ENSP00000384371 ProSitePatterns PS00028 IPR007087 604 624 - Zinc finger, C2H2
ENSP00000384371 ProSitePatterns PS00028 IPR007087 632 652 - Zinc finger, C2H2
ENSP00000384371 ProSitePatterns PS00028 IPR007087 660 681 - Zinc finger, C2H2
ENSP00000384371 ProSiteProfiles PS50097 IPR000210 32 99 0.00e-00 BTB/POZ-like
ENSP00000384371 ProSiteProfiles PS50157 IPR007087 518 546 0.00e-00 Zinc finger, C2H2
ENSP00000384371 ProSiteProfiles PS50157 IPR007087 546 573 0.00e-00 Zinc finger, C2H2
ENSP00000384371 ProSiteProfiles PS50157 IPR007087 574 601 0.00e-00 Zinc finger, C2H2
ENSP00000384371 ProSiteProfiles PS50157 IPR007087 602 629 0.00e-00 Zinc finger, C2H2
ENSP00000384371 ProSiteProfiles PS50157 IPR007087 630 657 0.00e-00 Zinc finger, C2H2
ENSP00000384371 ProSiteProfiles PS50157 IPR007087 658 681 0.00e-00 Zinc finger, C2H2
ENSP00000384371 SMART SM00225 IPR000210 32 129 1.20e-30 BTB/POZ-like
ENSP00000384371 SMART SM00355 IPR015880 518 541 4.60e-04 Zinc finger, C2H2-like
ENSP00000384371 SMART SM00355 IPR015880 546 568 5.60e-05 Zinc finger, C2H2-like
ENSP00000384371 SMART SM00355 IPR015880 574 596 9.40e-07 Zinc finger, C2H2-like
ENSP00000384371 SMART SM00355 IPR015880 602 624 1.30e-05 Zinc finger, C2H2-like
ENSP00000384371 SMART SM00355 IPR015880 630 652 2.80e-06 Zinc finger, C2H2-like
ENSP00000384371 SMART SM00355 IPR015880 658 681 1.30e-04 Zinc finger, C2H2-like
ENSP00000384371 SUPERFAMILY SSF54695 IPR011333 8 126 0.00e-00 BTB/POZ fold

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000384371 PF00651 1.5e-27 BTB BTB/POZ domain
ENSP00000384371 PF13465 8.5e-25 zf-H2C2_2 Zinc-finger double domain
ENSP00000384371 PF00096 8e-19 zf-C2H2 Zinc finger, C2H2 type
ENSP00000384371 PF13894 1.2e-11 zf-C2H2_4 C2H2-type zinc finger
ENSP00000384371 PF12874 2.8e-11 zf-met Zinc-finger of C2H2 type
ENSP00000384371 PF12171 3.3e-10 zf-C2H2_jaz Zinc-finger double-stranded RNA-binding

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000384371 GO:0006351 biological_process transcription, DNA-templated
ENSP00000384371 GO:0005634 cellular_component nucleus
ENSP00000384371 GO:0003677 molecular_function DNA binding
ENSP00000384371 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9823 Sus scrofa 100156549 8128 Oreochromis niloticus 100697595
10141 Cavia porcellus 100731135 9597 Pan paniscus 100984155
9555 Papio anubis 101019119 39432 Saimiri boliviensis 101034308
9669 Mustela putorius furo 101675563 8083 Xiphophorus maculatus 102236759
59463 Myotis lucifugus 102425929 13735 Pelodiscus sinensis 102450488
10090 Mus musculus 12029 9598 Pan troglodytes 460926
9986 Oryctolagus cuniculus 100353941 10029 Cricetulus griseus 100773755
9685 Felis catus 101096665 8090 Oryzias latipes 101162277
9913 Bos taurus 539020 9544 Macaca mulatta 708736
9615 Canis familiaris ENSCAFG00000013904 7719 Ciona intestinalis ENSCING00000007627
69293 Gasterosteus aculeatus ENSGACG00000003839 9785 Loxodonta africana ENSLAFG00000012300
9103 Meleagris gallopavo ENSMGAG00000007602 13616 Monodelphis domestica ENSMODG00000006161
30611 Otolemur garnettii ENSOGAG00000007638 132908 Pteropus vampyrus ENSPVAG00000012338
42254 Sorex araneus ENSSARG00000014055 43179 Ictidomys tridecemlineatus ENSSTOG00000000843
99883 Tetraodon nigroviridis ENSTNIG00000013771 31033 Takifugu rubripes ENSTRUG00000002214
30538 Vicugna pacos ENSVPAG00000003583 8364 Xenopus tropicalis ENSXETG00000019779
28377 Anolis carolinensis ENSACAG00000006666 9646 Ailuropoda melanoleuca ENSAMEG00000000812
9358 Choloepus hoffmanni ENSCHOG00000013361 9483 Callithrix jacchus ENSCJAG00000016905
51511 Ciona savignyi ENSCSAVG00000006275 7955 Danio rerio ENSDARG00000069335
9361 Dasypus novemcinctus ENSDNOG00000004306 10020 Dipodomys ordii ENSDORG00000005608
9796 Equus caballus ENSECAG00000004556 9365 Erinaceus europaeus ENSEEUG00000000344
9371 Echinops telfairi ENSETEG00000014830 9031 Gallus gallus ENSGALG00000007357
9595 Gorilla gorilla ENSGGOG00000026549 8049 Gadus morhua ENSGMOG00000019214
7897 Latimeria chalumnae ENSLACG00000004278 9315 Macropus eugenii ENSMEUG00000004411
30608 Microcebus murinus ENSMICG00000001780 9258 Ornithorhynchus anatinus ENSOANG00000000872
9978 Ochotona princeps ENSOPRG00000005797 9813 Procavia capensis ENSPCAG00000007666
9601 Pongo abelii ENSPPYG00000014395 9305 Sarcophilus harrisii ENSSHAG00000013935
37347 Tupaia belangeri ENSTBEG00000009526 9739 Tursiops truncatus ENSTTRG00000017230