Basic Information
Gene ID 60641
Gene Name sox9a
Full Name HMG box transcription factor Sox9a
Organism Danio rerio [7955]

Cross Reference
UniProt Q9DFH2 UniGene Dr.80814
PDB NULL OMIM NULL
KEGG dre:60641 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSDARP00000006945 Gene3D G3DSA:1.10.30.10 IPR009071 105 185 1.80e-33 High mobility group box domain
ENSDARP00000006945 Pfam PF00505 IPR009071 107 175 3.50e-24 High mobility group box domain
ENSDARP00000006945 Pfam PF12444 IPR022151 22 97 8.40e-28 Sox developmental protein N-terminal
ENSDARP00000006945 ProSiteProfiles PS50118 IPR009071 107 175 0.00e-00 High mobility group box domain
ENSDARP00000006945 SMART SM00398 IPR009071 106 176 1.20e-28 High mobility group box domain
ENSDARP00000006945 SUPERFAMILY SSF47095 IPR009071 89 179 0.00e-00 High mobility group box domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSDARP00000006945 PF12444 8.4e-28 Sox_N Sox developmental protein N terminal
ENSDARP00000006945 PF00505 1.8e-24 HMG_box HMG (high mobility group) box
ENSDARP00000006945 PF09011 2e-10 HMG_box_2 HMG-box domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSDARP00000006945 GO:0001501 biological_process skeletal system development
ENSDARP00000006945 GO:0001502 biological_process cartilage condensation
ENSDARP00000006945 GO:0001708 biological_process cell fate specification
ENSDARP00000006945 GO:0001837 biological_process epithelial to mesenchymal transition
ENSDARP00000006945 GO:0001894 biological_process tissue homeostasis
ENSDARP00000006945 GO:0001934 biological_process positive regulation of protein phosphorylation
ENSDARP00000006945 GO:0001942 biological_process hair follicle development
ENSDARP00000006945 GO:0002053 biological_process positive regulation of mesenchymal cell proliferation
ENSDARP00000006945 GO:0002683 biological_process negative regulation of immune system process
ENSDARP00000006945 GO:0003170 biological_process heart valve development
ENSDARP00000006945 GO:0003179 biological_process heart valve morphogenesis
ENSDARP00000006945 GO:0003203 biological_process endocardial cushion morphogenesis
ENSDARP00000006945 GO:0003413 biological_process chondrocyte differentiation involved in endochondral bone morphogenesis
ENSDARP00000006945 GO:0003415 biological_process chondrocyte hypertrophy
ENSDARP00000006945 GO:0006334 biological_process nucleosome assembly
ENSDARP00000006945 GO:0006338 biological_process chromatin remodeling
ENSDARP00000006945 GO:0006351 biological_process transcription, DNA-templated
ENSDARP00000006945 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSDARP00000006945 GO:0006366 biological_process transcription from RNA polymerase II promoter
ENSDARP00000006945 GO:0006461 biological_process protein complex assembly
ENSDARP00000006945 GO:0006468 biological_process protein phosphorylation
ENSDARP00000006945 GO:0007165 biological_process signal transduction
ENSDARP00000006945 GO:0007173 biological_process epidermal growth factor receptor signaling pathway
ENSDARP00000006945 GO:0007283 biological_process spermatogenesis
ENSDARP00000006945 GO:0008284 biological_process positive regulation of cell proliferation
ENSDARP00000006945 GO:0010564 biological_process regulation of cell cycle process
ENSDARP00000006945 GO:0010634 biological_process positive regulation of epithelial cell migration
ENSDARP00000006945 GO:0014068 biological_process positive regulation of phosphatidylinositol 3-kinase signaling
ENSDARP00000006945 GO:0019100 biological_process male germ-line sex determination
ENSDARP00000006945 GO:0019933 biological_process cAMP-mediated signaling
ENSDARP00000006945 GO:0030279 biological_process negative regulation of ossification
ENSDARP00000006945 GO:0030858 biological_process positive regulation of epithelial cell differentiation
ENSDARP00000006945 GO:0030916 biological_process otic vesicle formation
ENSDARP00000006945 GO:0032331 biological_process negative regulation of chondrocyte differentiation
ENSDARP00000006945 GO:0032332 biological_process positive regulation of chondrocyte differentiation
ENSDARP00000006945 GO:0035019 biological_process somatic stem cell maintenance
ENSDARP00000006945 GO:0042127 biological_process regulation of cell proliferation
ENSDARP00000006945 GO:0042981 biological_process regulation of apoptotic process
ENSDARP00000006945 GO:0043066 biological_process negative regulation of apoptotic process
ENSDARP00000006945 GO:0043491 biological_process protein kinase B signaling
ENSDARP00000006945 GO:0045662 biological_process negative regulation of myoblast differentiation
ENSDARP00000006945 GO:0045892 biological_process negative regulation of transcription, DNA-templated
ENSDARP00000006945 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSDARP00000006945 GO:0046533 biological_process negative regulation of photoreceptor cell differentiation
ENSDARP00000006945 GO:0050679 biological_process positive regulation of epithelial cell proliferation
ENSDARP00000006945 GO:0050680 biological_process negative regulation of epithelial cell proliferation
ENSDARP00000006945 GO:0051216 biological_process cartilage development
ENSDARP00000006945 GO:0060008 biological_process Sertoli cell differentiation
ENSDARP00000006945 GO:0060041 biological_process retina development in camera-type eye
ENSDARP00000006945 GO:0060221 biological_process retinal rod cell differentiation
ENSDARP00000006945 GO:0060517 biological_process epithelial cell proliferation involved in prostatic bud elongation
ENSDARP00000006945 GO:0060729 biological_process intestinal epithelial structure maintenance
ENSDARP00000006945 GO:0060784 biological_process regulation of cell proliferation involved in tissue homeostasis
ENSDARP00000006945 GO:0061138 biological_process morphogenesis of a branching epithelium
ENSDARP00000006945 GO:0070168 biological_process negative regulation of biomineral tissue development
ENSDARP00000006945 GO:0070371 biological_process ERK1 and ERK2 cascade
ENSDARP00000006945 GO:0071260 biological_process cellular response to mechanical stimulus
ENSDARP00000006945 GO:0071364 biological_process cellular response to epidermal growth factor stimulus
ENSDARP00000006945 GO:0071504 biological_process cellular response to heparin
ENSDARP00000006945 GO:0072034 biological_process renal vesicle induction
ENSDARP00000006945 GO:0072289 biological_process metanephric nephron tubule formation
ENSDARP00000006945 GO:0090090 biological_process negative regulation of canonical Wnt signaling pathway
ENSDARP00000006945 GO:0090103 biological_process cochlea morphogenesis
ENSDARP00000006945 GO:0090184 biological_process positive regulation of kidney development
ENSDARP00000006945 GO:0090190 biological_process positive regulation of branching involved in ureteric bud morphogenesis
ENSDARP00000006945 GO:2000020 biological_process positive regulation of male gonad development
ENSDARP00000006945 GO:2000741 biological_process positive regulation of mesenchymal stem cell differentiation
ENSDARP00000006945 GO:0005634 cellular_component nucleus
ENSDARP00000006945 GO:0043234 cellular_component protein complex
ENSDARP00000006945 GO:0001046 molecular_function core promoter sequence-specific DNA binding
ENSDARP00000006945 GO:0001077 molecular_function RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
ENSDARP00000006945 GO:0001158 molecular_function enhancer sequence-specific DNA binding
ENSDARP00000006945 GO:0003677 molecular_function DNA binding
ENSDARP00000006945 GO:0003682 molecular_function chromatin binding
ENSDARP00000006945 GO:0003705 molecular_function RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
ENSDARP00000006945 GO:0004672 molecular_function protein kinase activity
ENSDARP00000006945 GO:0035326 molecular_function enhancer binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10224 Saccoglossus kowalevskii 100367276 7029 Acyrthosiphon pisum 100572600
30195 Bombus terrestris 100649351 132113 Bombus impatiens 100746111
143995 Megachile rotundata 100875001 39432 Saimiri boliviensis 101044084
9595 Gorilla gorilla 101135517 43179 Ictidomys tridecemlineatus 101970684
8083 Xiphophorus maculatus 102219562 13616 Monodelphis domestica 100024115
9601 Pongo abelii 100452528 8128 Oreochromis niloticus 100693400
9555 Papio anubis 101003954 7897 Latimeria chalumnae 102351194
28377 Anolis carolinensis ENSACAG00000008719 9646 Ailuropoda melanoleuca ENSAMEG00000016948
9913 Bos taurus ENSBTAG00000045824 9483 Callithrix jacchus ENSCJAG00000000109
10020 Dipodomys ordii ENSDORG00000012440 9796 Equus caballus ENSECAG00000022037
9371 Echinops telfairi ENSETEG00000020237 9685 Felis catus ENSFCAG00000015685
69293 Gasterosteus aculeatus ENSGACG00000005675 8049 Gadus morhua ENSGMOG00000009261
9315 Macropus eugenii ENSMEUG00000009986 9986 Oryctolagus cuniculus ENSOCUG00000011639
30611 Otolemur garnettii ENSOGAG00000027844 9598 Pan troglodytes ENSPTRG00000009592
9305 Sarcophilus harrisii ENSSHAG00000018176 59729 Taeniopygia guttata ENSTGUG00000002882
31033 Takifugu rubripes ENSTRUG00000017157 7460 Apis mellifera 727284
9615 Canis familiaris ENSCAFG00000004374 7719 Ciona intestinalis ENSCING00000001019
51511 Ciona savignyi ENSCSAVG00000008424 9785 Loxodonta africana ENSLAFG00000001445
9103 Meleagris gallopavo ENSMGAG00000006638 9544 Macaca mulatta ENSMMUG00000002412
9669 Mustela putorius furo ENSMPUG00000014303 61853 Nomascus leucogenys ENSNLEG00000002643
9978 Ochotona princeps ENSOPRG00000007860 8090 Oryzias latipes ENSORLG00000007960
13735 Pelodiscus sinensis ENSPSIG00000016802 9823 Sus scrofa ENSSSCG00000017251
37347 Tupaia belangeri ENSTBEG00000000175 99883 Tetraodon nigroviridis ENSTNIG00000009759
9739 Tursiops truncatus ENSTTRG00000005687 30538 Vicugna pacos ENSVPAG00000000908
8364 Xenopus tropicalis ENSXETG00000022348