Basic Information
Gene ID 613025
Gene Name ESR1; EGK_15246
Full Name Estrogen receptor
Organism Macaca mulatta [9544]

Cross Reference
UniProt F6QUN5 UniGene Mmu.3492
PDB NULL OMIM NULL
KEGG mcc:613025 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
XP_002803904 Gene3D G3DSA:1.10.565.10 IPR008946 239 269 4.20e-101 Nuclear hormone receptor, ligand-binding
XP_002803904 Gene3D G3DSA:1.10.565.10 IPR008946 311 548 4.20e-101 Nuclear hormone receptor, ligand-binding
XP_002803904 Gene3D G3DSA:3.30.50.10 IPR013088 185 238 9.60e-28 Zinc finger, NHR/GATA-type
XP_002803904 Pfam PF00104 IPR000536 327 524 4.60e-29 Nuclear hormone receptor, ligand-binding, core
XP_002803904 Pfam PF00105 IPR001628 184 252 2.20e-31 Zinc finger, nuclear hormone receptor-type
XP_002803904 Pfam PF02159 IPR001292 42 181 9.20e-52 Oestrogen receptor
XP_002803904 Pfam PF12743 IPR024736 552 595 3.20e-21 Oestrogen-type nuclear receptor final C-terminal domain
XP_002803904 PIRSF PIRSF002527 IPR024178 42 590 3.20e-295 Oestrogen receptor/oestrogen-related receptor
XP_002803904 PIRSF PIRSF500101 IPR001292 1 595 0.00e-00 Oestrogen receptor
XP_002803904 PRINTS PR00047 IPR001628 185 201 8.20e-17 Zinc finger, nuclear hormone receptor-type
XP_002803904 PRINTS PR00047 IPR001628 201 216 8.20e-17 Zinc finger, nuclear hormone receptor-type
XP_002803904 PRINTS PR00047 IPR001628 234 242 8.20e-17 Zinc finger, nuclear hormone receptor-type
XP_002803904 PRINTS PR00047 IPR001628 242 250 8.20e-17 Zinc finger, nuclear hormone receptor-type
XP_002803904 PRINTS PR00398 IPR001723 246 256 5.70e-27 Steroid hormone receptor
XP_002803904 PRINTS PR00398 IPR001723 349 370 5.70e-27 Steroid hormone receptor
XP_002803904 PRINTS PR00398 IPR001723 370 386 5.70e-27 Steroid hormone receptor
XP_002803904 PRINTS PR00398 IPR001723 438 453 5.70e-27 Steroid hormone receptor
XP_002803904 PRINTS PR00398 IPR001723 506 523 5.70e-27 Steroid hormone receptor
XP_002803904 PRINTS PR00543 IPR001292 115 131 5.00e-87 Oestrogen receptor
XP_002803904 PRINTS PR00543 IPR001292 132 151 5.00e-87 Oestrogen receptor
XP_002803904 PRINTS PR00543 IPR001292 153 172 5.00e-87 Oestrogen receptor
XP_002803904 PRINTS PR00543 IPR001292 26 43 5.00e-87 Oestrogen receptor
XP_002803904 PRINTS PR00543 IPR001292 45 62 5.00e-87 Oestrogen receptor
XP_002803904 PRINTS PR00543 IPR001292 6 24 5.00e-87 Oestrogen receptor
XP_002803904 PRINTS PR00543 IPR001292 70 85 5.00e-87 Oestrogen receptor
XP_002803904 PRINTS PR00543 IPR001292 97 111 5.00e-87 Oestrogen receptor
XP_002803904 ProSitePatterns PS00031 IPR001628 185 211 - Zinc finger, nuclear hormone receptor-type
XP_002803904 ProSiteProfiles PS51030 IPR001628 182 257 0.00e-00 Zinc finger, nuclear hormone receptor-type
XP_002803904 SMART SM00399 IPR001628 182 253 6.40e-40 Zinc finger, nuclear hormone receptor-type
XP_002803904 SMART SM00430 IPR000536 348 518 2.30e-37 Nuclear hormone receptor, ligand-binding, core
XP_002803904 SUPERFAMILY SSF48508 IPR008946 235 261 0.00e-00 Nuclear hormone receptor, ligand-binding
XP_002803904 SUPERFAMILY SSF48508 IPR008946 302 547 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
XP_002803904 PF02159 0 Oest_recep Oestrogen receptor
XP_002803904 PF00105 1.4e-31 zf-C4 Zinc finger, C4 type (two domains)
XP_002803904 PF00104 3e-29 Hormone_recep Ligand-binding domain of nuclear hormone receptor
XP_002803904 PF12743 1.7e-21 ESR1_C Oestrogen-type nuclear receptor final C-terminal

Gene Ontology Annotation
Protein Entry Name Space Description
XP_002803904 GO:0006351 biological_process transcription, DNA-templated
XP_002803904 GO:0006355 biological_process regulation of transcription, DNA-templated
XP_002803904 GO:0007200 biological_process phospholipase C-activating G-protein coupled receptor signaling pathway
XP_002803904 GO:0007204 biological_process positive regulation of cytosolic calcium ion concentration
XP_002803904 GO:0010863 biological_process positive regulation of phospholipase C activity
XP_002803904 GO:0030518 biological_process intracellular steroid hormone receptor signaling pathway
XP_002803904 GO:0043124 biological_process negative regulation of I-kappaB kinase/NF-kappaB signaling
XP_002803904 GO:0043433 biological_process negative regulation of sequence-specific DNA binding transcription factor activity
XP_002803904 GO:0045429 biological_process positive regulation of nitric oxide biosynthetic process
XP_002803904 GO:0051000 biological_process positive regulation of nitric-oxide synthase activity
XP_002803904 GO:0051091 biological_process positive regulation of sequence-specific DNA binding transcription factor activity
XP_002803904 GO:0071392 biological_process cellular response to estradiol stimulus
XP_002803904 GO:0005634 cellular_component nucleus
XP_002803904 GO:0005794 cellular_component Golgi apparatus
XP_002803904 GO:0005886 cellular_component plasma membrane
XP_002803904 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
XP_002803904 GO:0003707 molecular_function steroid hormone receptor activity
XP_002803904 GO:0005496 molecular_function steroid binding
XP_002803904 GO:0008270 molecular_function zinc ion binding
XP_002803904 GO:0030284 molecular_function estrogen receptor activity
XP_002803904 GO:0043565 molecular_function sequence-specific DNA binding