Basic Information | |||
Gene ID | 6258 ; Check Expression Profles ; Check TFs & Targets Binding | ||
Gene Name | RXRG; NR2B3 | ||
Full Name | Retinoic acid receptor RXR-gamma | ||
Organism | Homo sapiens [9606] |
Cross Reference | |||
UniProt | P48443 | UniGene | Hs.26550 |
PDB | 2GL8 | OMIM | 180247 |
KEGG | hsa:6258 | UCSC | uc001gda.3 |
Protein Interactions | |
DIP | DIP-56220N |
IntAct | P48443 |
MINT | MINT-1378806 |
STRING | 9606.ENSP00000352900 |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSP00000352900 | Gene3D | G3DSA:1.10.565.10 | IPR008946 | 233 | 459 | 9.40e-104 | Nuclear hormone receptor, ligand-binding |
ENSP00000352900 | Gene3D | G3DSA:3.30.50.10 | IPR013088 | 135 | 217 | 1.40e-33 | Zinc finger, NHR/GATA-type |
ENSP00000352900 | Pfam | PF00104 | IPR000536 | 261 | 443 | 1.10e-40 | Nuclear hormone receptor, ligand-binding, core |
ENSP00000352900 | Pfam | PF00105 | IPR001628 | 138 | 206 | 1.90e-31 | Zinc finger, nuclear hormone receptor-type |
ENSP00000352900 | Pfam | PF11825 | IPR021780 | 24 | 134 | 1.00e-32 | Nuclear/hormone receptor activator site AF-1 |
ENSP00000352900 | PRINTS | PR00047 | IPR001628 | 139 | 155 | 1.40e-18 | Zinc finger, nuclear hormone receptor-type |
ENSP00000352900 | PRINTS | PR00047 | IPR001628 | 155 | 170 | 1.40e-18 | Zinc finger, nuclear hormone receptor-type |
ENSP00000352900 | PRINTS | PR00047 | IPR001628 | 188 | 196 | 1.40e-18 | Zinc finger, nuclear hormone receptor-type |
ENSP00000352900 | PRINTS | PR00047 | IPR001628 | 196 | 204 | 1.40e-18 | Zinc finger, nuclear hormone receptor-type |
ENSP00000352900 | PRINTS | PR00398 | IPR001723 | 200 | 210 | 5.40e-35 | Steroid hormone receptor |
ENSP00000352900 | PRINTS | PR00398 | IPR001723 | 272 | 293 | 5.40e-35 | Steroid hormone receptor |
ENSP00000352900 | PRINTS | PR00398 | IPR001723 | 293 | 309 | 5.40e-35 | Steroid hormone receptor |
ENSP00000352900 | PRINTS | PR00398 | IPR001723 | 361 | 376 | 5.40e-35 | Steroid hormone receptor |
ENSP00000352900 | PRINTS | PR00398 | IPR001723 | 418 | 435 | 5.40e-35 | Steroid hormone receptor |
ENSP00000352900 | PRINTS | PR00545 | IPR000003 | 207 | 220 | 1.90e-39 | Retinoid X receptor/HNF4 |
ENSP00000352900 | PRINTS | PR00545 | IPR000003 | 323 | 348 | 1.90e-39 | Retinoid X receptor/HNF4 |
ENSP00000352900 | PRINTS | PR00545 | IPR000003 | 349 | 367 | 1.90e-39 | Retinoid X receptor/HNF4 |
ENSP00000352900 | PRINTS | PR00545 | IPR000003 | 390 | 409 | 1.90e-39 | Retinoid X receptor/HNF4 |
ENSP00000352900 | ProSitePatterns | PS00031 | IPR001628 | 139 | 165 | - | Zinc finger, nuclear hormone receptor-type |
ENSP00000352900 | ProSiteProfiles | PS51030 | IPR001628 | 136 | 211 | 0.00e-00 | Zinc finger, nuclear hormone receptor-type |
ENSP00000352900 | SMART | SM00399 | IPR001628 | 136 | 207 | 2.30e-41 | Zinc finger, nuclear hormone receptor-type |
ENSP00000352900 | SMART | SM00430 | IPR000536 | 271 | 430 | 9.00e-53 | Nuclear hormone receptor, ligand-binding, core |
ENSP00000352900 | SUPERFAMILY | SSF48508 | IPR008946 | 189 | 457 | 0.00e-00 | Nuclear hormone receptor, ligand-binding |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSP00000352900 | PF00104 | 7.89996e-41 | Hormone_recep | Ligand-binding domain of nuclear hormone receptor |
ENSP00000352900 | PF11825 | 4.8e-33 | Nuc_recep-AF1 | Nuclear/hormone receptor activator site AF-1 |
ENSP00000352900 | PF00105 | 1.1e-31 | zf-C4 | Zinc finger, C4 type (two domains) |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
ENSP00000352900 | GO:0005634 | cellular_component | nucleus |
ENSP00000352900 | GO:0003707 | molecular_function | steroid hormone receptor activity |
ENSP00000352900 | GO:0008270 | molecular_function | zinc ion binding |
ENSP00000352900 | GO:0043565 | molecular_function | sequence-specific DNA binding |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
9483 | Callithrix jacchus | 100386851 | 61853 | Nomascus leucogenys | 100592610 |
9595 | Gorilla gorilla | 101152695 | 43179 | Ictidomys tridecemlineatus | 101957499 |
8083 | Xiphophorus maculatus | 102222228 | 6087 | Hydra magnipapillata | 100212284 |
9597 | Pan paniscus | 100992346 | 9555 | Papio anubis | 101015058 |
39432 | Saimiri boliviensis | 101040247 | 9685 | Felis catus | 101081273 |
9669 | Mustela putorius furo | 101693923 | 13735 | Pelodiscus sinensis | 102447903 |
9823 | Sus scrofa | 445465 | 9598 | Pan troglodytes | 457476 |
9615 | Canis familiaris | 478989 | 8364 | Xenopus tropicalis | 779621 |
10116 | Rattus norvegicus | 83574 | 9796 | Equus caballus | ENSECAG00000024377 |
69293 | Gasterosteus aculeatus | ENSGACG00000011685 | 9031 | Gallus gallus | ENSGALG00000003406 |
8049 | Gadus morhua | ENSGMOG00000018023 | 9785 | Loxodonta africana | ENSLAFG00000008059 |
9103 | Meleagris gallopavo | ENSMGAG00000003715 | 9986 | Oryctolagus cuniculus | ENSOCUG00000005512 |
8128 | Oreochromis niloticus | ENSONIG00000002143 | 9978 | Ochotona princeps | ENSOPRG00000014490 |
9813 | Procavia capensis | ENSPCAG00000008619 | 132908 | Pteropus vampyrus | ENSPVAG00000007457 |
9305 | Sarcophilus harrisii | ENSSHAG00000015367 | 37347 | Tupaia belangeri | ENSTBEG00000002797 |
9739 | Tursiops truncatus | ENSTTRG00000003653 | 30538 | Vicugna pacos | ENSVPAG00000004578 |
9544 | Macaca mulatta | 694807 | 9646 | Ailuropoda melanoleuca | ENSAMEG00000006616 |
9358 | Choloepus hoffmanni | ENSCHOG00000009952 | 10020 | Dipodomys ordii | ENSDORG00000014034 |
9365 | Erinaceus europaeus | ENSEEUG00000015558 | 9371 | Echinops telfairi | ENSETEG00000004886 |
9315 | Macropus eugenii | ENSMEUG00000013948 | 30608 | Microcebus murinus | ENSMICG00000009970 |
13616 | Monodelphis domestica | ENSMODG00000001291 | 30611 | Otolemur garnettii | ENSOGAG00000011318 |
8090 | Oryzias latipes | ENSORLG00000016690 | 9601 | Pongo abelii | ENSPPYG00000000571 |
9478 | Tarsius syrichta | ENSTSYG00000002120 |
Paralogs | |||
6256 | 6257 |