Basic Information
Gene ID 6258 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name RXRG; NR2B3
Full Name Retinoic acid receptor RXR-gamma
Organism Homo sapiens [9606]

Cross Reference
UniProt P48443 UniGene Hs.26550
PDB 2GL8 OMIM 180247
KEGG hsa:6258 UCSC uc001gda.3

Protein Interactions
DIP DIP-56220N
IntAct P48443
MINT MINT-1378806
STRING 9606.ENSP00000352900

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000352900 Gene3D G3DSA:1.10.565.10 IPR008946 233 459 9.40e-104 Nuclear hormone receptor, ligand-binding
ENSP00000352900 Gene3D G3DSA:3.30.50.10 IPR013088 135 217 1.40e-33 Zinc finger, NHR/GATA-type
ENSP00000352900 Pfam PF00104 IPR000536 261 443 1.10e-40 Nuclear hormone receptor, ligand-binding, core
ENSP00000352900 Pfam PF00105 IPR001628 138 206 1.90e-31 Zinc finger, nuclear hormone receptor-type
ENSP00000352900 Pfam PF11825 IPR021780 24 134 1.00e-32 Nuclear/hormone receptor activator site AF-1
ENSP00000352900 PRINTS PR00047 IPR001628 139 155 1.40e-18 Zinc finger, nuclear hormone receptor-type
ENSP00000352900 PRINTS PR00047 IPR001628 155 170 1.40e-18 Zinc finger, nuclear hormone receptor-type
ENSP00000352900 PRINTS PR00047 IPR001628 188 196 1.40e-18 Zinc finger, nuclear hormone receptor-type
ENSP00000352900 PRINTS PR00047 IPR001628 196 204 1.40e-18 Zinc finger, nuclear hormone receptor-type
ENSP00000352900 PRINTS PR00398 IPR001723 200 210 5.40e-35 Steroid hormone receptor
ENSP00000352900 PRINTS PR00398 IPR001723 272 293 5.40e-35 Steroid hormone receptor
ENSP00000352900 PRINTS PR00398 IPR001723 293 309 5.40e-35 Steroid hormone receptor
ENSP00000352900 PRINTS PR00398 IPR001723 361 376 5.40e-35 Steroid hormone receptor
ENSP00000352900 PRINTS PR00398 IPR001723 418 435 5.40e-35 Steroid hormone receptor
ENSP00000352900 PRINTS PR00545 IPR000003 207 220 1.90e-39 Retinoid X receptor/HNF4
ENSP00000352900 PRINTS PR00545 IPR000003 323 348 1.90e-39 Retinoid X receptor/HNF4
ENSP00000352900 PRINTS PR00545 IPR000003 349 367 1.90e-39 Retinoid X receptor/HNF4
ENSP00000352900 PRINTS PR00545 IPR000003 390 409 1.90e-39 Retinoid X receptor/HNF4
ENSP00000352900 ProSitePatterns PS00031 IPR001628 139 165 - Zinc finger, nuclear hormone receptor-type
ENSP00000352900 ProSiteProfiles PS51030 IPR001628 136 211 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSP00000352900 SMART SM00399 IPR001628 136 207 2.30e-41 Zinc finger, nuclear hormone receptor-type
ENSP00000352900 SMART SM00430 IPR000536 271 430 9.00e-53 Nuclear hormone receptor, ligand-binding, core
ENSP00000352900 SUPERFAMILY SSF48508 IPR008946 189 457 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000352900 PF00104 7.89996e-41 Hormone_recep Ligand-binding domain of nuclear hormone receptor
ENSP00000352900 PF11825 4.8e-33 Nuc_recep-AF1 Nuclear/hormone receptor activator site AF-1
ENSP00000352900 PF00105 1.1e-31 zf-C4 Zinc finger, C4 type (two domains)

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000352900 GO:0005634 cellular_component nucleus
ENSP00000352900 GO:0003707 molecular_function steroid hormone receptor activity
ENSP00000352900 GO:0008270 molecular_function zinc ion binding
ENSP00000352900 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9483 Callithrix jacchus 100386851 61853 Nomascus leucogenys 100592610
9595 Gorilla gorilla 101152695 43179 Ictidomys tridecemlineatus 101957499
8083 Xiphophorus maculatus 102222228 6087 Hydra magnipapillata 100212284
9597 Pan paniscus 100992346 9555 Papio anubis 101015058
39432 Saimiri boliviensis 101040247 9685 Felis catus 101081273
9669 Mustela putorius furo 101693923 13735 Pelodiscus sinensis 102447903
9823 Sus scrofa 445465 9598 Pan troglodytes 457476
9615 Canis familiaris 478989 8364 Xenopus tropicalis 779621
10116 Rattus norvegicus 83574 9796 Equus caballus ENSECAG00000024377
69293 Gasterosteus aculeatus ENSGACG00000011685 9031 Gallus gallus ENSGALG00000003406
8049 Gadus morhua ENSGMOG00000018023 9785 Loxodonta africana ENSLAFG00000008059
9103 Meleagris gallopavo ENSMGAG00000003715 9986 Oryctolagus cuniculus ENSOCUG00000005512
8128 Oreochromis niloticus ENSONIG00000002143 9978 Ochotona princeps ENSOPRG00000014490
9813 Procavia capensis ENSPCAG00000008619 132908 Pteropus vampyrus ENSPVAG00000007457
9305 Sarcophilus harrisii ENSSHAG00000015367 37347 Tupaia belangeri ENSTBEG00000002797
9739 Tursiops truncatus ENSTTRG00000003653 30538 Vicugna pacos ENSVPAG00000004578
9544 Macaca mulatta 694807 9646 Ailuropoda melanoleuca ENSAMEG00000006616
9358 Choloepus hoffmanni ENSCHOG00000009952 10020 Dipodomys ordii ENSDORG00000014034
9365 Erinaceus europaeus ENSEEUG00000015558 9371 Echinops telfairi ENSETEG00000004886
9315 Macropus eugenii ENSMEUG00000013948 30608 Microcebus murinus ENSMICG00000009970
13616 Monodelphis domestica ENSMODG00000001291 30611 Otolemur garnettii ENSOGAG00000011318
8090 Oryzias latipes ENSORLG00000016690 9601 Pongo abelii ENSPPYG00000000571
9478 Tarsius syrichta ENSTSYG00000002120

Paralogs
6256 6257