Basic Information
Gene ID 6672 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name SP100
Full Name Nuclear autoantigen Sp-100
Organism Homo sapiens [9606]

Cross Reference
UniProt P23497 UniGene Hs.369056
PDB 1H5P OMIM 604585
KEGG hsa:6672 UCSC uc010zmb.2

Protein Interactions
DIP DIP-5983N
IntAct P23497
MINT MINT-1188807
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000343023 Gene3D G3DSA:1.20.920.10 IPR001487 771 871 1.70e-12 Bromodomain
ENSP00000343023 Gene3D G3DSA:3.10.390.10 IPR010919 591 680 3.60e-36 SAND domain-like
ENSP00000343023 Gene3D G3DSA:3.30.40.10 IPR013083 696 752 5.20e-10 Zinc finger, RING/FYVE/PHD-type
ENSP00000343023 Pfam PF00439 IPR001487 810 852 6.60e-06 Bromodomain
ENSP00000343023 Pfam PF01342 IPR000770 596 675 2.70e-29 SAND domain
ENSP00000343023 Pfam PF03172 IPR004865 48 150 1.60e-46 Sp100
ENSP00000343023 ProSitePatterns PS01359 IPR019786 705 745 - Zinc finger, PHD-type, conserved site
ENSP00000343023 ProSiteProfiles PS50016 IPR019787 702 748 0.00e-00 Zinc finger, PHD-finger
ENSP00000343023 ProSiteProfiles PS50864 IPR000770 595 676 0.00e-00 SAND domain
ENSP00000343023 ProSiteProfiles PS51414 IPR004865 33 149 0.00e-00 Sp100
ENSP00000343023 SMART SM00249 IPR001965 704 746 9.60e-11 Zinc finger, PHD-type
ENSP00000343023 SMART SM00258 IPR000770 603 676 4.90e-48 SAND domain
ENSP00000343023 SMART SM00297 IPR001487 772 873 9.10e-10 Bromodomain
ENSP00000343023 SUPERFAMILY SSF47370 IPR001487 768 874 0.00e-00 Bromodomain
ENSP00000343023 SUPERFAMILY SSF57903 IPR011011 680 749 0.00e-00 Zinc finger, FYVE/PHD-type
ENSP00000343023 SUPERFAMILY SSF63763 IPR010919 596 684 0.00e-00 SAND domain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000343023 PF03172 0 Sp100 Sp100 domain
ENSP00000343023 PF01342 9.7e-30 SAND SAND domain
ENSP00000343023 PF00439 1.2e-06 Bromodomain Bromodomain
ENSP00000343023 PF00628 2.5e-06 PHD PHD-finger

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000343023 GO:0006351 biological_process transcription, DNA-templated
ENSP00000343023 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSP00000343023 GO:0005634 cellular_component nucleus
ENSP00000343023 GO:0005737 cellular_component cytoplasm
ENSP00000343023 GO:0003677 molecular_function DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9597 Pan paniscus 100980555 39432 Saimiri boliviensis 101052681
9483 Callithrix jacchus ENSCJAG00000013324 9361 Dasypus novemcinctus ENSDNOG00000005741
9646 Ailuropoda melanoleuca ENSAMEG00000016480 9913 Bos taurus ENSBTAG00000037989
9615 Canis familiaris ENSCAFG00000010717 9358 Choloepus hoffmanni ENSCHOG00000011762
10020 Dipodomys ordii ENSDORG00000011093 9796 Equus caballus ENSECAG00000008186
9371 Echinops telfairi ENSETEG00000001893 9685 Felis catus ENSFCAG00000006266
9595 Gorilla gorilla ENSGGOG00000006712 30608 Microcebus murinus ENSMICG00000004106
9669 Mustela putorius furo ENSMPUG00000004541 61853 Nomascus leucogenys ENSNLEG00000013741
9986 Oryctolagus cuniculus ENSOCUG00000016930 30611 Otolemur garnettii ENSOGAG00000033014
9978 Ochotona princeps ENSOPRG00000008712 9813 Procavia capensis ENSPCAG00000007694
9601 Pongo abelii ENSPPYG00000013255 9598 Pan troglodytes ENSPTRG00000013012
132908 Pteropus vampyrus ENSPVAG00000003179 42254 Sorex araneus ENSSARG00000003300
9823 Sus scrofa ENSSSCG00000016263 43179 Ictidomys tridecemlineatus ENSSTOG00000005264
37347 Tupaia belangeri ENSTBEG00000006623 9478 Tarsius syrichta ENSTSYG00000009927
9739 Tursiops truncatus ENSTTRG00000014242

Paralogs
93349