Basic Information
Gene ID 668 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name FOXL2
Full Name Forkhead box protein L2
Organism Homo sapiens [9606]

Cross Reference
UniProt P58012 UniGene Hs.289292
PDB NULL OMIM 608996
KEGG hsa:668 UCSC uc003esw.3

Protein Interactions
DIP NULL
IntAct P58012
MINT NULL
STRING 9606.ENSP00000333188

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000333188 Gene3D G3DSA:1.10.10.10 IPR011991 48 141 9.00e-41 Winged helix-turn-helix DNA-binding domain
ENSP00000333188 Pfam PF00250 IPR001766 54 148 7.70e-41 Transcription factor, fork head
ENSP00000333188 PRINTS PR00053 IPR001766 54 67 2.60e-22 Transcription factor, fork head
ENSP00000333188 PRINTS PR00053 IPR001766 75 92 2.60e-22 Transcription factor, fork head
ENSP00000333188 PRINTS PR00053 IPR001766 98 115 2.60e-22 Transcription factor, fork head
ENSP00000333188 ProSitePatterns PS00657 IPR018122 54 67 - Transcription factor, fork head, conserved site
ENSP00000333188 ProSitePatterns PS00658 IPR018122 98 104 - Transcription factor, fork head, conserved site
ENSP00000333188 ProSiteProfiles PS50039 IPR001766 54 148 0.00e-00 Transcription factor, fork head
ENSP00000333188 SMART SM00339 IPR001766 52 142 9.00e-62 Transcription factor, fork head

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000333188 PF00250 5.10003e-41 Fork_head Fork head domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000333188 GO:0001541 biological_process ovarian follicle development
ENSP00000333188 GO:0002074 biological_process extraocular skeletal muscle development
ENSP00000333188 GO:0006309 biological_process apoptotic DNA fragmentation
ENSP00000333188 GO:0006351 biological_process transcription, DNA-templated
ENSP00000333188 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSP00000333188 GO:0030154 biological_process cell differentiation
ENSP00000333188 GO:0042703 biological_process menstruation
ENSP00000333188 GO:0043065 biological_process positive regulation of apoptotic process
ENSP00000333188 GO:0043280 biological_process positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
ENSP00000333188 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSP00000333188 GO:0005634 cellular_component nucleus
ENSP00000333188 GO:0003677 molecular_function DNA binding
ENSP00000333188 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSP00000333188 GO:0043028 molecular_function cysteine-type endopeptidase regulator activity involved in apoptotic process
ENSP00000333188 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100119258 8090 Oryzias latipes 100125429
59729 Taeniopygia guttata 100222465 7029 Acyrthosiphon pisum 100570810
30195 Bombus terrestris 100644911 7463 Apis florea 100872967
34638 Metaseiulus occidentalis 100908649 9555 Papio anubis 101007625
31033 Takifugu rubripes 101069066 8083 Xiphophorus maculatus 102229993
13735 Pelodiscus sinensis 102445818 10116 Rattus norvegicus 367152
9598 Pan troglodytes 470940 10224 Saccoglossus kowalevskii 100328989
8128 Oreochromis niloticus 100534517 9823 Sus scrofa 100622956
132113 Bombus impatiens 100742971 143995 Megachile rotundata 100874733
9597 Pan paniscus 100983147 39432 Saimiri boliviensis 101031228
7070 Tribolium castaneum 663700 9646 Ailuropoda melanoleuca ENSAMEG00000018717
7955 Danio rerio ENSDARG00000068417 9544 Macaca mulatta ENSMMUG00000031521
9258 Ornithorhynchus anatinus ENSOANG00000000312 132908 Pteropus vampyrus ENSPVAG00000012394
99883 Tetraodon nigroviridis ENSTNIG00000014321 7460 Apis mellifera 724740
7668 Strongylocentrotus purpuratus 751846 9615 Canis familiaris ENSCAFG00000007585
7719 Ciona intestinalis ENSCING00000004674 10141 Cavia porcellus ENSCPOG00000024451
51511 Ciona savignyi ENSCSAVG00000009393 9361 Dasypus novemcinctus ENSDNOG00000000720
69293 Gasterosteus aculeatus ENSGACG00000005639 9595 Gorilla gorilla ENSGGOG00000024690
8049 Gadus morhua ENSGMOG00000020081 7897 Latimeria chalumnae ENSLACG00000012021
7757 Petromyzon marinus ENSPMAG00000010223 43179 Ictidomys tridecemlineatus ENSSTOG00000026426
8364 Xenopus tropicalis ENSXETG00000008253