Basic Information | |||
Gene ID | 6736 ; Check Expression Profles ; Check TFs & Targets Binding | ||
Gene Name | SRY; TDF | ||
Full Name | Sex-determining region Y protein | ||
Organism | Homo sapiens [9606] |
Cross Reference | |||
UniProt | Q05066 | UniGene | Hs.1992 |
PDB | 2GZK | OMIM | 480000 |
KEGG | hsa:6736 | UCSC | uc004fqg.1 |
Protein Interactions | |
DIP | NULL |
IntAct | Q05066 |
MINT | MINT-1367278 |
STRING | 9606.ENSP00000372547 |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSP00000372547 | Gene3D | G3DSA:1.10.30.10 | IPR009071 | 59 | 138 | 5.50e-33 | High mobility group box domain |
ENSP00000372547 | PANTHER | PTHR10270:SF48 | IPR017253 | 46 | 167 | 0.00e-00 | Transcription factor Sry |
ENSP00000372547 | Pfam | PF00505 | IPR009071 | 60 | 128 | 1.30e-25 | High mobility group box domain |
ENSP00000372547 | PIRSF | PIRSF037653 | IPR017253 | 1 | 204 | 3.50e-145 | Transcription factor Sry |
ENSP00000372547 | ProSiteProfiles | PS50118 | IPR009071 | 60 | 128 | 0.00e-00 | High mobility group box domain |
ENSP00000372547 | SMART | SM00398 | IPR009071 | 59 | 129 | 7.50e-28 | High mobility group box domain |
ENSP00000372547 | SUPERFAMILY | SSF47095 | IPR009071 | 56 | 141 | 0.00e-00 | High mobility group box domain |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSP00000372547 | PF00505 | 8.1e-26 | HMG_box | HMG (high mobility group) box |
ENSP00000372547 | PF09011 | 1.7e-08 | HMG_box_2 | HMG-box domain |
ENSP00000372547 | PF08926 | 0.00036 | DUF1908 | Domain of unknown function (DUF1908) |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
ENSP00000372547 | GO:0006351 | biological_process | transcription, DNA-templated |
ENSP00000372547 | GO:0006355 | biological_process | regulation of transcription, DNA-templated |
ENSP00000372547 | GO:0007548 | biological_process | sex differentiation |
ENSP00000372547 | GO:0030154 | biological_process | cell differentiation |
ENSP00000372547 | GO:0030238 | biological_process | male sex determination |
ENSP00000372547 | GO:0005634 | cellular_component | nucleus |
ENSP00000372547 | GO:0005737 | cellular_component | cytoplasm |
ENSP00000372547 | GO:0016607 | cellular_component | nuclear speck |
ENSP00000372547 | GO:0003677 | molecular_function | DNA binding |
ENSP00000372547 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
ENSP00000372547 | GO:0005516 | molecular_function | calmodulin binding |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
9598 | Pan troglodytes | 449510 | 9823 | Sus scrofa | ENSSSCG00000028946 |