Basic Information
Gene ID 6736 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name SRY; TDF
Full Name Sex-determining region Y protein
Organism Homo sapiens [9606]

Cross Reference
UniProt Q05066 UniGene Hs.1992
PDB 2GZK OMIM 480000
KEGG hsa:6736 UCSC uc004fqg.1

Protein Interactions
DIP NULL
IntAct Q05066
MINT MINT-1367278
STRING 9606.ENSP00000372547

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000372547 Gene3D G3DSA:1.10.30.10 IPR009071 59 138 5.50e-33 High mobility group box domain
ENSP00000372547 PANTHER PTHR10270:SF48 IPR017253 46 167 0.00e-00 Transcription factor Sry
ENSP00000372547 Pfam PF00505 IPR009071 60 128 1.30e-25 High mobility group box domain
ENSP00000372547 PIRSF PIRSF037653 IPR017253 1 204 3.50e-145 Transcription factor Sry
ENSP00000372547 ProSiteProfiles PS50118 IPR009071 60 128 0.00e-00 High mobility group box domain
ENSP00000372547 SMART SM00398 IPR009071 59 129 7.50e-28 High mobility group box domain
ENSP00000372547 SUPERFAMILY SSF47095 IPR009071 56 141 0.00e-00 High mobility group box domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000372547 PF00505 8.1e-26 HMG_box HMG (high mobility group) box
ENSP00000372547 PF09011 1.7e-08 HMG_box_2 HMG-box domain
ENSP00000372547 PF08926 0.00036 DUF1908 Domain of unknown function (DUF1908)

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000372547 GO:0006351 biological_process transcription, DNA-templated
ENSP00000372547 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSP00000372547 GO:0007548 biological_process sex differentiation
ENSP00000372547 GO:0030154 biological_process cell differentiation
ENSP00000372547 GO:0030238 biological_process male sex determination
ENSP00000372547 GO:0005634 cellular_component nucleus
ENSP00000372547 GO:0005737 cellular_component cytoplasm
ENSP00000372547 GO:0016607 cellular_component nuclear speck
ENSP00000372547 GO:0003677 molecular_function DNA binding
ENSP00000372547 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSP00000372547 GO:0005516 molecular_function calmodulin binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9598 Pan troglodytes 449510 9823 Sus scrofa ENSSSCG00000028946