Basic Information | |||
Gene ID | 6777 ; ![]() ![]() | ||
Gene Name | STAT5B | ||
Full Name | Signal transducer and activator of transcription 5B | ||
Organism | Homo sapiens [9606] |
Cross Reference | |||
UniProt | P51692 | UniGene | Hs.595276 |
PDB | NULL | OMIM | 604260 |
KEGG | hsa:6777 | UCSC | uc002hzh.3 |
Protein Interactions | |
DIP | NULL |
IntAct | P51692 |
MINT | MINT-132900 |
STRING | 9606.ENSP00000293328 |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
NP_036580 | Gene3D | G3DSA:1.10.238.10 | IPR011992 | 472 | 597 | 1.70e-47 | EF-hand domain pair |
NP_036580 | Gene3D | G3DSA:1.10.532.10 | IPR013799 | 1 | 125 | 1.50e-47 | STAT transcription factor, protein interaction |
NP_036580 | Gene3D | G3DSA:1.20.1050.20 | IPR013800 | 139 | 332 | 1.60e-64 | STAT transcription factor, all-alpha |
NP_036580 | Gene3D | G3DSA:2.60.40.630 | IPR012345 | 333 | 471 | 5.90e-69 | STAT transcription factor, DNA-binding, subdomain |
NP_036580 | Gene3D | G3DSA:3.30.505.10 | IPR000980 | 598 | 712 | 6.70e-41 | SH2 domain |
NP_036580 | PANTHER | PTHR11801 | IPR001217 | 2 | 779 | 0.00e-00 | Transcription factor STAT |
NP_036580 | Pfam | PF00017 | IPR000980 | 595 | 667 | 1.80e-10 | SH2 domain |
NP_036580 | Pfam | PF01017 | IPR013800 | 138 | 330 | 1.90e-55 | STAT transcription factor, all-alpha |
NP_036580 | Pfam | PF02864 | IPR013801 | 332 | 583 | 3.70e-99 | STAT transcription factor, DNA-binding |
NP_036580 | Pfam | PF02865 | IPR013799 | 2 | 125 | 6.40e-47 | STAT transcription factor, protein interaction |
NP_036580 | ProSiteProfiles | PS50001 | IPR000980 | 589 | 686 | 0.00e-00 | SH2 domain |
NP_036580 | SMART | SM00252 | IPR000980 | 587 | 705 | 1.20e-07 | SH2 domain |
NP_036580 | SMART | SM00964 | IPR013799 | 2 | 126 | 7.60e-65 | STAT transcription factor, protein interaction |
NP_036580 | SUPERFAMILY | SSF47655 | IPR015988 | 136 | 332 | 0.00e-00 | STAT transcription factor, coiled coil |
NP_036580 | SUPERFAMILY | SSF48092 | IPR013799 | 1 | 124 | 0.00e-00 | STAT transcription factor, protein interaction |
NP_036580 | SUPERFAMILY | SSF49417 | IPR008967 | 327 | 584 | 0.00e-00 | p53-like transcription factor, DNA-binding |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
NP_036580 | PF01017 | 0 | STAT_alpha | STAT protein, all-alpha domain |
NP_036580 | PF02864 | 0 | STAT_bind | STAT protein, DNA binding domain |
NP_036580 | PF02865 | 0 | STAT_int | STAT protein, protein interaction domain |
NP_036580 | PF00017 | 6.1e-12 | SH2 | SH2 domain |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
NP_036580 | GO:0001553 | biological_process | luteinization |
NP_036580 | GO:0001779 | biological_process | natural killer cell differentiation |
NP_036580 | GO:0006351 | biological_process | transcription, DNA-templated |
NP_036580 | GO:0007259 | biological_process | JAK-STAT cascade |
NP_036580 | GO:0007565 | biological_process | female pregnancy |
NP_036580 | GO:0007595 | biological_process | lactation |
NP_036580 | GO:0019218 | biological_process | regulation of steroid metabolic process |
NP_036580 | GO:0019915 | biological_process | lipid storage |
NP_036580 | GO:0030155 | biological_process | regulation of cell adhesion |
NP_036580 | GO:0030856 | biological_process | regulation of epithelial cell differentiation |
NP_036580 | GO:0038161 | biological_process | prolactin signaling pathway |
NP_036580 | GO:0040018 | biological_process | positive regulation of multicellular organism growth |
NP_036580 | GO:0042104 | biological_process | positive regulation of activated T cell proliferation |
NP_036580 | GO:0043029 | biological_process | T cell homeostasis |
NP_036580 | GO:0043066 | biological_process | negative regulation of apoptotic process |
NP_036580 | GO:0045086 | biological_process | positive regulation of interleukin-2 biosynthetic process |
NP_036580 | GO:0045579 | biological_process | positive regulation of B cell differentiation |
NP_036580 | GO:0045647 | biological_process | negative regulation of erythrocyte differentiation |
NP_036580 | GO:0045931 | biological_process | positive regulation of mitotic cell cycle |
NP_036580 | GO:0045944 | biological_process | positive regulation of transcription from RNA polymerase II promoter |
NP_036580 | GO:0046543 | biological_process | development of secondary female sexual characteristics |
NP_036580 | GO:0050729 | biological_process | positive regulation of inflammatory response |
NP_036580 | GO:0005634 | cellular_component | nucleus |
NP_036580 | GO:0005737 | cellular_component | cytoplasm |
NP_036580 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
NP_036580 | GO:0004871 | molecular_function | signal transducer activity |
NP_036580 | GO:0005509 | molecular_function | calcium ion binding |