Basic Information | |||
Gene ID | 6911 ; Check Expression Profles ; Check TFs & Targets Binding | ||
Gene Name | TBX6 | ||
Full Name | T-box transcription factor TBX6 | ||
Organism | Homo sapiens [9606] |
Cross Reference | |||
UniProt | O95947 | UniGene | Hs.198301 |
PDB | NULL | OMIM | 602427 |
KEGG | hsa:6911 | UCSC | uc010veh.2 |
Protein Interactions | |
DIP | NULL |
IntAct | O95947 |
MINT | MINT-6772404 |
STRING | 9606.ENSP00000279386 |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
ENSEMBL | |||
REFSEQ | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSP00000279386 | Gene3D | G3DSA:2.60.40.820 | IPR001699 | 90 | 277 | 1.10e-84 | Transcription factor, T-box |
ENSP00000279386 | PANTHER | PTHR11267 | IPR001699 | 1 | 436 | 0.00e-00 | Transcription factor, T-box |
ENSP00000279386 | Pfam | PF00907 | IPR001699 | 93 | 274 | 4.50e-85 | Transcription factor, T-box |
ENSP00000279386 | PRINTS | PR00937 | IPR001699 | 108 | 132 | 3.80e-44 | Transcription factor, T-box |
ENSP00000279386 | PRINTS | PR00937 | IPR001699 | 173 | 186 | 3.80e-44 | Transcription factor, T-box |
ENSP00000279386 | PRINTS | PR00937 | IPR001699 | 190 | 199 | 3.80e-44 | Transcription factor, T-box |
ENSP00000279386 | PRINTS | PR00937 | IPR001699 | 209 | 223 | 3.80e-44 | Transcription factor, T-box |
ENSP00000279386 | PRINTS | PR00937 | IPR001699 | 244 | 257 | 3.80e-44 | Transcription factor, T-box |
ENSP00000279386 | PRINTS | PR00937 | IPR001699 | 265 | 273 | 3.80e-44 | Transcription factor, T-box |
ENSP00000279386 | PRINTS | PR00938 | IPR002070 | 153 | 173 | 4.10e-05 | Transcription factor, Brachyury |
ENSP00000279386 | PRINTS | PR00938 | IPR002070 | 214 | 231 | 4.10e-05 | Transcription factor, Brachyury |
ENSP00000279386 | ProSitePatterns | PS01264 | IPR018186 | 174 | 192 | - | Transcription factor, T-box, conserved site |
ENSP00000279386 | ProSitePatterns | PS01283 | IPR018186 | 100 | 119 | - | Transcription factor, T-box, conserved site |
ENSP00000279386 | ProSiteProfiles | PS50252 | IPR001699 | 95 | 273 | 0.00e-00 | Transcription factor, T-box |
ENSP00000279386 | SMART | SM00425 | IPR001699 | 90 | 278 | 1.50e-128 | Transcription factor, T-box |
ENSP00000279386 | SUPERFAMILY | SSF49417 | IPR008967 | 91 | 273 | 0.00e-00 | p53-like transcription factor, DNA-binding |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSP00000279386 | PF00907 | 0 | T-box | T-box |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
ENSP00000279386 | GO:0001707 | biological_process | mesoderm formation |
ENSP00000279386 | GO:0005634 | cellular_component | nucleus |
ENSP00000279386 | GO:0003677 | molecular_function | DNA binding |
ENSP00000279386 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
9597 | Pan paniscus | 100967383 | 9685 | Felis catus | 101080347 |
9598 | Pan troglodytes | 467944 | 9986 | Oryctolagus cuniculus | 100343206 |
10141 | Cavia porcellus | 100729853 | 30611 | Otolemur garnettii | 100957966 |
9555 | Papio anubis | 101006066 | 39432 | Saimiri boliviensis | 101037917 |
9595 | Gorilla gorilla | 101128452 | 9669 | Mustela putorius furo | 101681413 |
10090 | Mus musculus | 21389 | 7227 | Drosophila melanogaster | 39039 |
28377 | Anolis carolinensis | ENSACAG00000015031 | 9646 | Ailuropoda melanoleuca | ENSAMEG00000015253 |
9913 | Bos taurus | ENSBTAG00000009046 | 9615 | Canis familiaris | ENSCAFG00000017092 |
7719 | Ciona intestinalis | ENSCING00000023066 | 7955 | Danio rerio | ENSDARG00000007329 |
10020 | Dipodomys ordii | ENSDORG00000003367 | 9796 | Equus caballus | ENSECAG00000022374 |
9365 | Erinaceus europaeus | ENSEEUG00000012843 | 9371 | Echinops telfairi | ENSETEG00000019233 |
69293 | Gasterosteus aculeatus | ENSGACG00000012454 | 9031 | Gallus gallus | ENSGALG00000006374 |
8049 | Gadus morhua | ENSGMOG00000011095 | 7897 | Latimeria chalumnae | ENSLACG00000012884 |
9785 | Loxodonta africana | ENSLAFG00000017884 | 9315 | Macropus eugenii | ENSMEUG00000000414 |
30608 | Microcebus murinus | ENSMICG00000009134 | 59463 | Myotis lucifugus | ENSMLUG00000011244 |
61853 | Nomascus leucogenys | ENSNLEG00000002044 | 9258 | Ornithorhynchus anatinus | ENSOANG00000006061 |
8128 | Oreochromis niloticus | ENSONIG00000011439 | 9978 | Ochotona princeps | ENSOPRG00000009784 |
8090 | Oryzias latipes | ENSORLG00000006272 | 9813 | Procavia capensis | ENSPCAG00000000071 |
132908 | Pteropus vampyrus | ENSPVAG00000010556 | 9305 | Sarcophilus harrisii | ENSSHAG00000010802 |
43179 | Ictidomys tridecemlineatus | ENSSTOG00000000869 | 59729 | Taeniopygia guttata | ENSTGUG00000010188 |
99883 | Tetraodon nigroviridis | ENSTNIG00000015212 | 31033 | Takifugu rubripes | ENSTRUG00000008789 |
9739 | Tursiops truncatus | ENSTTRG00000005534 | 8083 | Xiphophorus maculatus | ENSXMAG00000013802 |
9544 | Macaca mulatta | ENSMMUG00000000981 | 9601 | Pongo abelii | ENSPPYG00000007242 |