Basic Information
Gene ID 6911 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name TBX6
Full Name T-box transcription factor TBX6
Organism Homo sapiens [9606]

Cross Reference
UniProt O95947 UniGene Hs.198301
PDB NULL OMIM 602427
KEGG hsa:6911 UCSC uc010veh.2

Protein Interactions
DIP NULL
IntAct O95947
MINT MINT-6772404
STRING 9606.ENSP00000279386

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000279386 Gene3D G3DSA:2.60.40.820 IPR001699 90 277 1.10e-84 Transcription factor, T-box
ENSP00000279386 PANTHER PTHR11267 IPR001699 1 436 0.00e-00 Transcription factor, T-box
ENSP00000279386 Pfam PF00907 IPR001699 93 274 4.50e-85 Transcription factor, T-box
ENSP00000279386 PRINTS PR00937 IPR001699 108 132 3.80e-44 Transcription factor, T-box
ENSP00000279386 PRINTS PR00937 IPR001699 173 186 3.80e-44 Transcription factor, T-box
ENSP00000279386 PRINTS PR00937 IPR001699 190 199 3.80e-44 Transcription factor, T-box
ENSP00000279386 PRINTS PR00937 IPR001699 209 223 3.80e-44 Transcription factor, T-box
ENSP00000279386 PRINTS PR00937 IPR001699 244 257 3.80e-44 Transcription factor, T-box
ENSP00000279386 PRINTS PR00937 IPR001699 265 273 3.80e-44 Transcription factor, T-box
ENSP00000279386 PRINTS PR00938 IPR002070 153 173 4.10e-05 Transcription factor, Brachyury
ENSP00000279386 PRINTS PR00938 IPR002070 214 231 4.10e-05 Transcription factor, Brachyury
ENSP00000279386 ProSitePatterns PS01264 IPR018186 174 192 - Transcription factor, T-box, conserved site
ENSP00000279386 ProSitePatterns PS01283 IPR018186 100 119 - Transcription factor, T-box, conserved site
ENSP00000279386 ProSiteProfiles PS50252 IPR001699 95 273 0.00e-00 Transcription factor, T-box
ENSP00000279386 SMART SM00425 IPR001699 90 278 1.50e-128 Transcription factor, T-box
ENSP00000279386 SUPERFAMILY SSF49417 IPR008967 91 273 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000279386 PF00907 0 T-box T-box

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000279386 GO:0001707 biological_process mesoderm formation
ENSP00000279386 GO:0005634 cellular_component nucleus
ENSP00000279386 GO:0003677 molecular_function DNA binding
ENSP00000279386 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9597 Pan paniscus 100967383 9685 Felis catus 101080347
9598 Pan troglodytes 467944 9986 Oryctolagus cuniculus 100343206
10141 Cavia porcellus 100729853 30611 Otolemur garnettii 100957966
9555 Papio anubis 101006066 39432 Saimiri boliviensis 101037917
9595 Gorilla gorilla 101128452 9669 Mustela putorius furo 101681413
10090 Mus musculus 21389 7227 Drosophila melanogaster 39039
28377 Anolis carolinensis ENSACAG00000015031 9646 Ailuropoda melanoleuca ENSAMEG00000015253
9913 Bos taurus ENSBTAG00000009046 9615 Canis familiaris ENSCAFG00000017092
7719 Ciona intestinalis ENSCING00000023066 7955 Danio rerio ENSDARG00000007329
10020 Dipodomys ordii ENSDORG00000003367 9796 Equus caballus ENSECAG00000022374
9365 Erinaceus europaeus ENSEEUG00000012843 9371 Echinops telfairi ENSETEG00000019233
69293 Gasterosteus aculeatus ENSGACG00000012454 9031 Gallus gallus ENSGALG00000006374
8049 Gadus morhua ENSGMOG00000011095 7897 Latimeria chalumnae ENSLACG00000012884
9785 Loxodonta africana ENSLAFG00000017884 9315 Macropus eugenii ENSMEUG00000000414
30608 Microcebus murinus ENSMICG00000009134 59463 Myotis lucifugus ENSMLUG00000011244
61853 Nomascus leucogenys ENSNLEG00000002044 9258 Ornithorhynchus anatinus ENSOANG00000006061
8128 Oreochromis niloticus ENSONIG00000011439 9978 Ochotona princeps ENSOPRG00000009784
8090 Oryzias latipes ENSORLG00000006272 9813 Procavia capensis ENSPCAG00000000071
132908 Pteropus vampyrus ENSPVAG00000010556 9305 Sarcophilus harrisii ENSSHAG00000010802
43179 Ictidomys tridecemlineatus ENSSTOG00000000869 59729 Taeniopygia guttata ENSTGUG00000010188
99883 Tetraodon nigroviridis ENSTNIG00000015212 31033 Takifugu rubripes ENSTRUG00000008789
9739 Tursiops truncatus ENSTTRG00000005534 8083 Xiphophorus maculatus ENSXMAG00000013802
9544 Macaca mulatta ENSMMUG00000000981 9601 Pongo abelii ENSPPYG00000007242