Basic Information
Gene ID 718970
Gene Name IRF3
Full Name Interferon regulatory factor 3
Organism Macaca mulatta [9544]

Cross Reference
UniProt B6CJX6 UniGene Mmu.925
PDB NULL OMIM NULL
KEGG mcc:718970 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 9544.ENSMMUP00000031524

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_001129269 Gene3D G3DSA:1.10.10.10 IPR011991 7 113 2.40e-38 Winged helix-turn-helix DNA-binding domain
NP_001129269 Gene3D G3DSA:2.60.200.10 IPR017855 186 419 3.80e-77 SMAD domain-like
NP_001129269 Pfam PF00605 IPR001346 7 111 4.10e-32 Interferon regulatory factor DNA-binding domain
NP_001129269 Pfam PF10401 IPR019471 197 374 9.10e-48 Interferon regulatory factor-3
NP_001129269 PRINTS PR00267 IPR001346 33 46 3.80e-17 Interferon regulatory factor DNA-binding domain
NP_001129269 PRINTS PR00267 IPR001346 50 67 3.80e-17 Interferon regulatory factor DNA-binding domain
NP_001129269 PRINTS PR00267 IPR001346 7 26 3.80e-17 Interferon regulatory factor DNA-binding domain
NP_001129269 PRINTS PR00267 IPR001346 73 95 3.80e-17 Interferon regulatory factor DNA-binding domain
NP_001129269 ProSitePatterns PS00601 IPR019817 26 58 - Interferon regulatory factor, conserved site
NP_001129269 ProSiteProfiles PS51507 IPR001346 5 111 0.00e-00 Interferon regulatory factor DNA-binding domain
NP_001129269 SMART SM00348 IPR001346 1 112 1.10e-55 Interferon regulatory factor DNA-binding domain
NP_001129269 SUPERFAMILY SSF49879 IPR008984 185 422 0.00e-00 SMAD/FHA domain

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_001129269 PF10401 0 IRF-3 Interferon-regulatory factor 3
NP_001129269 PF00605 2.7e-32 IRF Interferon regulatory factor transcription factor

Gene Ontology Annotation
Protein Entry Name Space Description
NP_001129269 GO:0006351 biological_process transcription, DNA-templated
NP_001129269 GO:0051607 biological_process defense response to virus
NP_001129269 GO:0005634 cellular_component nucleus
NP_001129269 GO:0005737 cellular_component cytoplasm
NP_001129269 GO:0000975 molecular_function regulatory region DNA binding
NP_001129269 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity