Basic Information
Gene ID 778905
Gene Name Ci-Smad4; smad4
Full Name Smad4
Organism Ciona intestinalis [7719]

Cross Reference
UniProt Q4H2T4 UniGene Cin.30504
PDB NULL OMIM NULL
KEGG cin:778905 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 7719.ENSCINP00000011519

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSCINP00000011529 Gene3D G3DSA:2.60.200.10 IPR017855 287 521 3.20e-112 SMAD domain-like
ENSCINP00000011529 Gene3D G3DSA:3.90.520.10 IPR013019 6 136 2.30e-51 MAD homology, MH1
ENSCINP00000011529 PANTHER PTHR13703 IPR013790 1 527 0.00e-00 Dwarfin
ENSCINP00000011529 Pfam PF03165 IPR003619 32 132 5.20e-39 MAD homology 1, Dwarfin-type
ENSCINP00000011529 Pfam PF03166 IPR001132 292 506 1.20e-73 SMAD domain, Dwarfin-type
ENSCINP00000011529 ProSiteProfiles PS51075 IPR013019 13 137 0.00e-00 MAD homology, MH1
ENSCINP00000011529 ProSiteProfiles PS51076 IPR001132 295 527 0.00e-00 SMAD domain, Dwarfin-type
ENSCINP00000011529 SMART SM00523 IPR003619 26 135 4.00e-65 MAD homology 1, Dwarfin-type
ENSCINP00000011529 SMART SM00524 IPR001132 293 505 1.80e-112 SMAD domain, Dwarfin-type
ENSCINP00000011529 SUPERFAMILY SSF49879 IPR008984 269 519 0.00e-00 SMAD/FHA domain
ENSCINP00000011529 SUPERFAMILY SSF56366 IPR013019 14 132 0.00e-00 MAD homology, MH1

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSCINP00000011529 PF03166 0 MH2 MH2 domain
ENSCINP00000011529 PF03165 2.7e-39 MH1 MH1 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSCINP00000011529 GO:0007179 biological_process transforming growth factor beta receptor signaling pathway
ENSCINP00000011529 GO:0005737 cellular_component cytoplasm
ENSCINP00000011529 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSCINP00000011529 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7029 Acyrthosiphon pisum 100158948 6087 Hydra magnipapillata 100198878
9483 Callithrix jacchus 100409302 28377 Anolis carolinensis 100552093
400682 Amphimedon queenslandica 100637596 8128 Oreochromis niloticus 100708381
132113 Bombus impatiens 100745462 7463 Apis florea 100869046
34638 Metaseiulus occidentalis 100903134 9597 Pan paniscus 100991127
9555 Papio anubis 101019266 9685 Felis catus 101093650
8083 Xiphophorus maculatus 102228719 7897 Latimeria chalumnae 102358988
10090 Mus musculus 17128 7460 Apis mellifera 409321
7227 Drosophila melanogaster 43725 7668 Strongylocentrotus purpuratus 575230
7070 Tribolium castaneum 660074 9796 Equus caballus 100033846
10224 Saccoglossus kowalevskii 100369846 30195 Bombus terrestris 100644192
9785 Loxodonta africana 100659509 143995 Megachile rotundata 100879968
39432 Saimiri boliviensis 101032066 9595 Gorilla gorilla 101153595
9669 Mustela putorius furo 101675099 13735 Pelodiscus sinensis 102451711
9598 Pan troglodytes 468537 9544 Macaca mulatta 701803
7955 Danio rerio ENSDARG00000023527 9361 Dasypus novemcinctus ENSDNOG00000005063
9365 Erinaceus europaeus ENSEEUG00000001575 13616 Monodelphis domestica ENSMODG00000010995
8090 Oryzias latipes ENSORLG00000005020 10116 Rattus norvegicus ENSRNOG00000015634
9305 Sarcophilus harrisii ENSSHAG00000010344 31033 Takifugu rubripes ENSTRUG00000014045
9478 Tarsius syrichta ENSTSYG00000009792 9739 Tursiops truncatus ENSTTRG00000011767
9358 Choloepus hoffmanni ENSCHOG00000000860 10141 Cavia porcellus ENSCPOG00000006470
51511 Ciona savignyi ENSCSAVG00000006480 10020 Dipodomys ordii ENSDORG00000009089
9371 Echinops telfairi ENSETEG00000007750 69293 Gasterosteus aculeatus ENSGACG00000007495
8049 Gadus morhua ENSGMOG00000005844 9315 Macropus eugenii ENSMEUG00000001823
30608 Microcebus murinus ENSMICG00000017525 59463 Myotis lucifugus ENSMLUG00000013944
9258 Ornithorhynchus anatinus ENSOANG00000008117 9978 Ochotona princeps ENSOPRG00000013601
9813 Procavia capensis ENSPCAG00000009142 7757 Petromyzon marinus ENSPMAG00000009414
132908 Pteropus vampyrus ENSPVAG00000004261 42254 Sorex araneus ENSSARG00000013883
43179 Ictidomys tridecemlineatus ENSSTOG00000028580 37347 Tupaia belangeri ENSTBEG00000014105
99883 Tetraodon nigroviridis ENSTNIG00000003193 30538 Vicugna pacos ENSVPAG00000006757
8364 Xenopus tropicalis ENSXETG00000022355