Basic Information
Gene ID 78968 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Srebf1; Srebp1
Full Name Sterol regulatory element-binding protein 1
Organism Rattus norvegicus [10116]

Cross Reference
UniProt P56720 UniGene Rn.198857
PDB NULL OMIM NULL
KEGG rno:78968 UCSC RGD:69423

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSRNOP00000050057 Gene3D G3DSA:4.10.280.10 IPR011598 315 385 1.40e-24 Myc-type, basic helix-loop-helix (bHLH) domain
ENSRNOP00000050057 Pfam PF00010 IPR011598 318 368 1.30e-16 Myc-type, basic helix-loop-helix (bHLH) domain
ENSRNOP00000050057 ProSiteProfiles PS50888 IPR011598 317 367 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSRNOP00000050057 SMART SM00353 IPR011598 323 373 2.20e-18 Myc-type, basic helix-loop-helix (bHLH) domain
ENSRNOP00000050057 SUPERFAMILY SSF47459 IPR011598 314 384 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSRNOP00000050057 PF00010 6.3e-17 HLH Helix-loop-helix DNA-binding domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSRNOP00000050057 GO:0006351 biological_process transcription, DNA-templated
ENSRNOP00000050057 GO:0006629 biological_process lipid metabolic process
ENSRNOP00000050057 GO:0008203 biological_process cholesterol metabolic process
ENSRNOP00000050057 GO:0000139 cellular_component Golgi membrane
ENSRNOP00000050057 GO:0005634 cellular_component nucleus
ENSRNOP00000050057 GO:0005783 cellular_component endoplasmic reticulum
ENSRNOP00000050057 GO:0005789 cellular_component endoplasmic reticulum membrane
ENSRNOP00000050057 GO:0012507 cellular_component ER to Golgi transport vesicle membrane
ENSRNOP00000050057 GO:0016021 cellular_component integral component of membrane
ENSRNOP00000050057 GO:0003677 molecular_function DNA binding
ENSRNOP00000050057 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100124259 10029 Cricetulus griseus 100689018
34638 Metaseiulus occidentalis 100903126 9597 Pan paniscus 100974159
9555 Papio anubis 101013905 10090 Mus musculus 20787
9615 Canis familiaris 403475 7070 Tribolium castaneum 663039
9646 Ailuropoda melanoleuca ENSAMEG00000005129 9595 Gorilla gorilla ENSGGOG00000002713
9669 Mustela putorius furo ENSMPUG00000000024 61853 Nomascus leucogenys ENSNLEG00000013625
9305 Sarcophilus harrisii ENSSHAG00000018607 31033 Takifugu rubripes ENSTRUG00000008197
8364 Xenopus tropicalis ENSXETG00000012160 28377 Anolis carolinensis ENSACAG00000001181
9913 Bos taurus ENSBTAG00000007884 10141 Cavia porcellus ENSCPOG00000002439
7955 Danio rerio ENSDARG00000067607 10020 Dipodomys ordii ENSDORG00000012333
9796 Equus caballus ENSECAG00000019802 9371 Echinops telfairi ENSETEG00000004179
9685 Felis catus ENSFCAG00000001983 69293 Gasterosteus aculeatus ENSGACG00000012064
9031 Gallus gallus ENSGALG00000027188 8049 Gadus morhua ENSGMOG00000011626
7897 Latimeria chalumnae ENSLACG00000013149 9785 Loxodonta africana ENSLAFG00000021644
9315 Macropus eugenii ENSMEUG00000001306 30608 Microcebus murinus ENSMICG00000012535
9544 Macaca mulatta ENSMMUG00000023375 13616 Monodelphis domestica ENSMODG00000014074
9258 Ornithorhynchus anatinus ENSOANG00000012278 30611 Otolemur garnettii ENSOGAG00000002910
8128 Oreochromis niloticus ENSONIG00000002304 9978 Ochotona princeps ENSOPRG00000015069
8090 Oryzias latipes ENSORLG00000009437 9813 Procavia capensis ENSPCAG00000014903
7757 Petromyzon marinus ENSPMAG00000001400 9601 Pongo abelii ENSPPYG00000008037
13735 Pelodiscus sinensis ENSPSIG00000005996 132908 Pteropus vampyrus ENSPVAG00000005765
43179 Ictidomys tridecemlineatus ENSSTOG00000014939 99883 Tetraodon nigroviridis ENSTNIG00000011957