Basic Information
Gene ID 7942 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name TFEB; BHLHE35
Full Name Transcription factor EB
Organism Homo sapiens [9606]

Cross Reference
UniProt P19484 UniGene Hs.485360
PDB NULL OMIM 600744
KEGG hsa:7942 UCSC uc003oqs.1

Protein Interactions
DIP NULL
IntAct P19484
MINT NULL
STRING 9606.ENSP00000230323

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000351742 Gene3D G3DSA:4.10.280.10 IPR011598 249 306 2.20e-22 Myc-type, basic helix-loop-helix (bHLH) domain
ENSP00000351742 PANTHER PTHR10014 IPR024097 5 490 0.00e-00 Basic helix-loop-helix leucine zipper transcription factor
ENSP00000351742 PANTHER PTHR10014:SF9 IPR024098 5 490 0.00e-00 Transcription factor EB
ENSP00000351742 Pfam PF00010 IPR011598 250 303 7.50e-15 Myc-type, basic helix-loop-helix (bHLH) domain
ENSP00000351742 Pfam PF11851 IPR021802 335 488 4.60e-35 Basic helix-loop-helix leucine zipper transcrition factor MiT/TFE
ENSP00000351742 ProSiteProfiles PS50888 IPR011598 249 302 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSP00000351742 SMART SM00353 IPR011598 255 308 4.90e-18 Myc-type, basic helix-loop-helix (bHLH) domain
ENSP00000351742 SUPERFAMILY SSF47459 IPR011598 243 312 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000351742 PF11851 4.6e-35 DUF3371 Domain of unknown function (DUF3371)
ENSP00000351742 PF00010 3.2e-15 HLH Helix-loop-helix DNA-binding domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000351742 GO:0006351 biological_process transcription, DNA-templated
ENSP00000351742 GO:0005634 cellular_component nucleus
ENSP00000351742 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
8128 Oreochromis niloticus 100696335 10029 Cricetulus griseus 100769893
9544 Macaca mulatta 694214 9598 Pan troglodytes 748433
9555 Papio anubis 100137208 9597 Pan paniscus 100973991
39432 Saimiri boliviensis 101046155 9685 Felis catus 101099802
9669 Mustela putorius furo 101693795 8083 Xiphophorus maculatus 102219652
10116 Rattus norvegicus 316214 9913 Bos taurus ENSBTAG00000012384
7719 Ciona intestinalis ENSCING00000004702 10141 Cavia porcellus ENSCPOG00000008027
9796 Equus caballus ENSECAG00000019762 9371 Echinops telfairi ENSETEG00000018481
69293 Gasterosteus aculeatus ENSGACG00000000364 9031 Gallus gallus ENSGALG00000003404
7897 Latimeria chalumnae ENSLACG00000013218 9315 Macropus eugenii ENSMEUG00000004173
9103 Meleagris gallopavo ENSMGAG00000006159 30608 Microcebus murinus ENSMICG00000015674
59463 Myotis lucifugus ENSMLUG00000000232 9258 Ornithorhynchus anatinus ENSOANG00000015438
9986 Oryctolagus cuniculus ENSOCUG00000027474 30611 Otolemur garnettii ENSOGAG00000010116
9978 Ochotona princeps ENSOPRG00000004894 9601 Pongo abelii ENSPPYG00000016599
13735 Pelodiscus sinensis ENSPSIG00000010995 37347 Tupaia belangeri ENSTBEG00000005895
31033 Takifugu rubripes ENSTRUG00000000653 9646 Ailuropoda melanoleuca ENSAMEG00000013103
9483 Callithrix jacchus ENSCJAG00000004199 9365 Erinaceus europaeus ENSEEUG00000008669
9595 Gorilla gorilla ENSGGOG00000002683 8049 Gadus morhua ENSGMOG00000016466
9785 Loxodonta africana ENSLAFG00000003059 13616 Monodelphis domestica ENSMODG00000012916
61853 Nomascus leucogenys ENSNLEG00000004906 8090 Oryzias latipes ENSORLG00000015866
9813 Procavia capensis ENSPCAG00000016749 132908 Pteropus vampyrus ENSPVAG00000007581
9305 Sarcophilus harrisii ENSSHAG00000009705 9823 Sus scrofa ENSSSCG00000001621
43179 Ictidomys tridecemlineatus ENSSTOG00000015338 59729 Taeniopygia guttata ENSTGUG00000017433
99883 Tetraodon nigroviridis ENSTNIG00000007281 9739 Tursiops truncatus ENSTTRG00000016385
8364 Xenopus tropicalis ENSXETG00000011854