Basic Information | |||
Gene ID | 7942 ; Check Expression Profles ; Check TFs & Targets Binding | ||
Gene Name | TFEB; BHLHE35 | ||
Full Name | Transcription factor EB | ||
Organism | Homo sapiens [9606] |
Cross Reference | |||
UniProt | P19484 | UniGene | Hs.485360 |
PDB | NULL | OMIM | 600744 |
KEGG | hsa:7942 | UCSC | uc003oqs.1 |
Protein Interactions | |
DIP | NULL |
IntAct | P19484 |
MINT | NULL |
STRING | 9606.ENSP00000230323 |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSP00000351742 | Gene3D | G3DSA:4.10.280.10 | IPR011598 | 249 | 306 | 2.20e-22 | Myc-type, basic helix-loop-helix (bHLH) domain |
ENSP00000351742 | PANTHER | PTHR10014 | IPR024097 | 5 | 490 | 0.00e-00 | Basic helix-loop-helix leucine zipper transcription factor |
ENSP00000351742 | PANTHER | PTHR10014:SF9 | IPR024098 | 5 | 490 | 0.00e-00 | Transcription factor EB |
ENSP00000351742 | Pfam | PF00010 | IPR011598 | 250 | 303 | 7.50e-15 | Myc-type, basic helix-loop-helix (bHLH) domain |
ENSP00000351742 | Pfam | PF11851 | IPR021802 | 335 | 488 | 4.60e-35 | Basic helix-loop-helix leucine zipper transcrition factor MiT/TFE |
ENSP00000351742 | ProSiteProfiles | PS50888 | IPR011598 | 249 | 302 | 0.00e-00 | Myc-type, basic helix-loop-helix (bHLH) domain |
ENSP00000351742 | SMART | SM00353 | IPR011598 | 255 | 308 | 4.90e-18 | Myc-type, basic helix-loop-helix (bHLH) domain |
ENSP00000351742 | SUPERFAMILY | SSF47459 | IPR011598 | 243 | 312 | 0.00e-00 | Myc-type, basic helix-loop-helix (bHLH) domain |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSP00000351742 | PF11851 | 4.6e-35 | DUF3371 | Domain of unknown function (DUF3371) |
ENSP00000351742 | PF00010 | 3.2e-15 | HLH | Helix-loop-helix DNA-binding domain |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
ENSP00000351742 | GO:0006351 | biological_process | transcription, DNA-templated |
ENSP00000351742 | GO:0005634 | cellular_component | nucleus |
ENSP00000351742 | GO:0046983 | molecular_function | protein dimerization activity |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
8128 | Oreochromis niloticus | 100696335 | 10029 | Cricetulus griseus | 100769893 |
9544 | Macaca mulatta | 694214 | 9598 | Pan troglodytes | 748433 |
9555 | Papio anubis | 100137208 | 9597 | Pan paniscus | 100973991 |
39432 | Saimiri boliviensis | 101046155 | 9685 | Felis catus | 101099802 |
9669 | Mustela putorius furo | 101693795 | 8083 | Xiphophorus maculatus | 102219652 |
10116 | Rattus norvegicus | 316214 | 9913 | Bos taurus | ENSBTAG00000012384 |
7719 | Ciona intestinalis | ENSCING00000004702 | 10141 | Cavia porcellus | ENSCPOG00000008027 |
9796 | Equus caballus | ENSECAG00000019762 | 9371 | Echinops telfairi | ENSETEG00000018481 |
69293 | Gasterosteus aculeatus | ENSGACG00000000364 | 9031 | Gallus gallus | ENSGALG00000003404 |
7897 | Latimeria chalumnae | ENSLACG00000013218 | 9315 | Macropus eugenii | ENSMEUG00000004173 |
9103 | Meleagris gallopavo | ENSMGAG00000006159 | 30608 | Microcebus murinus | ENSMICG00000015674 |
59463 | Myotis lucifugus | ENSMLUG00000000232 | 9258 | Ornithorhynchus anatinus | ENSOANG00000015438 |
9986 | Oryctolagus cuniculus | ENSOCUG00000027474 | 30611 | Otolemur garnettii | ENSOGAG00000010116 |
9978 | Ochotona princeps | ENSOPRG00000004894 | 9601 | Pongo abelii | ENSPPYG00000016599 |
13735 | Pelodiscus sinensis | ENSPSIG00000010995 | 37347 | Tupaia belangeri | ENSTBEG00000005895 |
31033 | Takifugu rubripes | ENSTRUG00000000653 | 9646 | Ailuropoda melanoleuca | ENSAMEG00000013103 |
9483 | Callithrix jacchus | ENSCJAG00000004199 | 9365 | Erinaceus europaeus | ENSEEUG00000008669 |
9595 | Gorilla gorilla | ENSGGOG00000002683 | 8049 | Gadus morhua | ENSGMOG00000016466 |
9785 | Loxodonta africana | ENSLAFG00000003059 | 13616 | Monodelphis domestica | ENSMODG00000012916 |
61853 | Nomascus leucogenys | ENSNLEG00000004906 | 8090 | Oryzias latipes | ENSORLG00000015866 |
9813 | Procavia capensis | ENSPCAG00000016749 | 132908 | Pteropus vampyrus | ENSPVAG00000007581 |
9305 | Sarcophilus harrisii | ENSSHAG00000009705 | 9823 | Sus scrofa | ENSSSCG00000001621 |
43179 | Ictidomys tridecemlineatus | ENSSTOG00000015338 | 59729 | Taeniopygia guttata | ENSTGUG00000017433 |
99883 | Tetraodon nigroviridis | ENSTNIG00000007281 | 9739 | Tursiops truncatus | ENSTTRG00000016385 |
8364 | Xenopus tropicalis | ENSXETG00000011854 |