Basic Information
Gene ID 8427 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name ZNF282; HUB1
Full Name Zinc finger protein 282
Organism Homo sapiens [9606]

Cross Reference
UniProt Q9UDV7 UniGene Hs.729056
PDB NULL OMIM 603397
KEGG hsa:8427 UCSC uc003wfm.3

Protein Interactions
DIP NULL
IntAct Q9UDV7
MINT MINT-8247561
STRING 9606.ENSP00000262085

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000262085 Gene3D G3DSA:3.30.160.60 IPR013087 516 547 3.10e-14 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000262085 Gene3D G3DSA:3.30.160.60 IPR013087 548 574 2.40e-14 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000262085 Gene3D G3DSA:3.30.160.60 IPR013087 575 593 1.50e-13 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000262085 Gene3D G3DSA:3.30.160.60 IPR013087 594 620 2.20e-17 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000262085 Gene3D G3DSA:3.30.160.60 IPR013087 621 654 1.00e-15 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000262085 Pfam PF01352 IPR001909 198 238 3.60e-17 Krueppel-associated box
ENSP00000262085 Pfam PF12417 IPR022137 93 170 9.30e-13 Protein of unknown function DUF3669, zinc finger protein
ENSP00000262085 ProSitePatterns PS00028 IPR007087 520 540 - Zinc finger, C2H2
ENSP00000262085 ProSitePatterns PS00028 IPR007087 548 568 - Zinc finger, C2H2
ENSP00000262085 ProSitePatterns PS00028 IPR007087 576 596 - Zinc finger, C2H2
ENSP00000262085 ProSitePatterns PS00028 IPR007087 604 624 - Zinc finger, C2H2
ENSP00000262085 ProSitePatterns PS00028 IPR007087 632 652 - Zinc finger, C2H2
ENSP00000262085 ProSiteProfiles PS50157 IPR007087 518 545 0.00e-00 Zinc finger, C2H2
ENSP00000262085 ProSiteProfiles PS50157 IPR007087 546 573 0.00e-00 Zinc finger, C2H2
ENSP00000262085 ProSiteProfiles PS50157 IPR007087 574 601 0.00e-00 Zinc finger, C2H2
ENSP00000262085 ProSiteProfiles PS50157 IPR007087 602 629 0.00e-00 Zinc finger, C2H2
ENSP00000262085 ProSiteProfiles PS50157 IPR007087 630 657 0.00e-00 Zinc finger, C2H2
ENSP00000262085 ProSiteProfiles PS50805 IPR001909 198 271 0.00e-00 Krueppel-associated box
ENSP00000262085 SMART SM00349 IPR001909 198 260 3.20e-25 Krueppel-associated box
ENSP00000262085 SMART SM00355 IPR015880 518 540 2.40e-06 Zinc finger, C2H2-like
ENSP00000262085 SMART SM00355 IPR015880 546 568 1.60e-04 Zinc finger, C2H2-like
ENSP00000262085 SMART SM00355 IPR015880 574 596 3.60e-06 Zinc finger, C2H2-like
ENSP00000262085 SMART SM00355 IPR015880 602 624 1.40e-06 Zinc finger, C2H2-like
ENSP00000262085 SMART SM00355 IPR015880 630 652 3.60e-07 Zinc finger, C2H2-like
ENSP00000262085 SUPERFAMILY SSF109640 IPR001909 194 244 0.00e-00 Krueppel-associated box

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000262085 PF13465 7.8e-35 zf-H2C2_2 Zinc-finger double domain
ENSP00000262085 PF00096 3.2e-25 zf-C2H2 Zinc finger, C2H2 type
ENSP00000262085 PF01352 1.8e-17 KRAB KRAB box
ENSP00000262085 PF13894 5.4e-14 zf-C2H2_4 C2H2-type zinc finger
ENSP00000262085 PF12417 4.9e-13 DUF3669 Zinc finger protein
ENSP00000262085 PF13912 3.7e-10 zf-C2H2_6 C2H2-type zinc finger
ENSP00000262085 PF12171 0.00015 zf-C2H2_jaz Zinc-finger double-stranded RNA-binding

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000262085 GO:0006351 biological_process transcription, DNA-templated
ENSP00000262085 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSP00000262085 GO:0005634 cellular_component nucleus
ENSP00000262085 GO:0003677 molecular_function DNA binding
ENSP00000262085 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9555 Papio anubis 101004874 10090 Mus musculus 101095
9597 Pan paniscus 100969061 39432 Saimiri boliviensis 101042796
10116 Rattus norvegicus 297065 9544 Macaca mulatta 710270
28377 Anolis carolinensis ENSACAG00000006602 9646 Ailuropoda melanoleuca ENSAMEG00000002702
9913 Bos taurus ENSBTAG00000020448 9483 Callithrix jacchus ENSCJAG00000010222
10141 Cavia porcellus ENSCPOG00000006586 9361 Dasypus novemcinctus ENSDNOG00000008361
10020 Dipodomys ordii ENSDORG00000016708 9685 Felis catus ENSFCAG00000007550
9785 Loxodonta africana ENSLAFG00000029727 9103 Meleagris gallopavo ENSMGAG00000001163
30608 Microcebus murinus ENSMICG00000016620 59463 Myotis lucifugus ENSMLUG00000010622
13616 Monodelphis domestica ENSMODG00000001987 9669 Mustela putorius furo ENSMPUG00000006666
61853 Nomascus leucogenys ENSNLEG00000003706 9258 Ornithorhynchus anatinus ENSOANG00000015269
9986 Oryctolagus cuniculus ENSOCUG00000008423 30611 Otolemur garnettii ENSOGAG00000030129
9813 Procavia capensis ENSPCAG00000010115 9601 Pongo abelii ENSPPYG00000018151
13735 Pelodiscus sinensis ENSPSIG00000002479 132908 Pteropus vampyrus ENSPVAG00000010866
37347 Tupaia belangeri ENSTBEG00000000091 9978 Ochotona princeps ENSOPRG00000010540
9305 Sarcophilus harrisii ENSSHAG00000018278 9823 Sus scrofa ENSSSCG00000016773
43179 Ictidomys tridecemlineatus ENSSTOG00000021295 9739 Tursiops truncatus ENSTTRG00000015685