Basic Information
Gene ID 8431 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name NR0B2; SHP
Full Name Nuclear receptor subfamily 0 group B member 2
Organism Homo sapiens [9606]

Cross Reference
UniProt Q15466 UniGene Hs.427055
PDB 4DOR OMIM 604630
KEGG hsa:8431 UCSC uc001bnf.3

Protein Interactions
DIP DIP-46313N
IntAct Q15466
MINT MINT-8150838
STRING 9606.ENSP00000254227

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_068804 Gene3D G3DSA:1.10.565.10 IPR008946 28 254 1.20e-37 Nuclear hormone receptor, ligand-binding
NP_068804 Pfam PF00104 IPR000536 63 228 7.30e-15 Nuclear hormone receptor, ligand-binding, core
NP_068804 PRINTS PR00398 IPR001723 159 174 8.80e-10 Steroid hormone receptor
NP_068804 PRINTS PR00398 IPR001723 216 233 8.80e-10 Steroid hormone receptor
NP_068804 PRINTS PR00398 IPR001723 58 79 8.80e-10 Steroid hormone receptor
NP_068804 PRINTS PR00398 IPR001723 79 95 8.80e-10 Steroid hormone receptor
NP_068804 SMART SM00430 IPR000536 57 228 3.00e-20 Nuclear hormone receptor, ligand-binding, core
NP_068804 SUPERFAMILY SSF48508 IPR008946 26 254 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_068804 PF00104 3.2e-15 Hormone_recep Ligand-binding domain of nuclear hormone receptor

Gene Ontology Annotation
Protein Entry Name Space Description
NP_068804 GO:0006694 biological_process steroid biosynthetic process
NP_068804 GO:0008104 biological_process protein localization
NP_068804 GO:0008406 biological_process gonad development
NP_068804 GO:0008584 biological_process male gonad development
NP_068804 GO:0030325 biological_process adrenal gland development
NP_068804 GO:0030522 biological_process intracellular receptor signaling pathway
NP_068804 GO:0033144 biological_process negative regulation of intracellular steroid hormone receptor signaling pathway
NP_068804 GO:0045892 biological_process negative regulation of transcription, DNA-templated
NP_068804 GO:0005634 cellular_component nucleus
NP_068804 GO:0005737 cellular_component cytoplasm
NP_068804 GO:0016020 cellular_component membrane
NP_068804 GO:0042788 cellular_component polysomal ribosome
NP_068804 GO:0003677 molecular_function DNA binding
NP_068804 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
NP_068804 GO:0003707 molecular_function steroid hormone receptor activity
NP_068804 GO:0003723 molecular_function RNA binding
NP_068804 GO:0004879 molecular_function ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
NP_068804 GO:0019904 molecular_function protein domain specific binding
NP_068804 GO:0032448 molecular_function DNA hairpin binding
NP_068804 GO:0035258 molecular_function steroid hormone receptor binding
NP_068804 GO:0042803 molecular_function protein homodimerization activity
NP_068804 GO:0043565 molecular_function sequence-specific DNA binding