Basic Information
Gene ID 91012 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name CERS5; LASS5
Full Name Ceramide synthase 5
Organism Homo sapiens [9606]

Cross Reference
UniProt Q8N5B7 UniGene Hs.270525
PDB NULL OMIM 615335
KEGG hsa:91012 UCSC uc001rwd.4

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 9606.ENSP00000325485

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000325485 Gene3D G3DSA:1.10.10.60 IPR009057 90 134 1.30e-10 Homeodomain-like
ENSP00000325485 Pfam PF00046 IPR001356 90 134 1.50e-08 Homeobox domain
ENSP00000325485 Pfam PF03798 IPR006634 140 333 7.00e-38 TRAM/LAG1/CLN8 homology domain
ENSP00000325485 PIRSF PIRSF005225 IPR016439 5 378 3.20e-149 Longevity assurance, LAG1/LAC1
ENSP00000325485 ProSiteProfiles PS50071 IPR001356 92 136 0.00e-00 Homeobox domain
ENSP00000325485 ProSiteProfiles PS50922 IPR006634 139 340 0.00e-00 TRAM/LAG1/CLN8 homology domain
ENSP00000325485 SMART SM00389 IPR001356 82 140 2.10e-04 Homeobox domain
ENSP00000325485 SMART SM00724 IPR006634 139 340 1.10e-77 TRAM/LAG1/CLN8 homology domain
ENSP00000325485 SUPERFAMILY SSF46689 IPR009057 83 134 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000325485 PF03798 5.4e-38 TRAM_LAG1_CLN8 TLC domain
ENSP00000325485 PF00046 9.3e-09 Homeobox Homeobox domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000325485 GO:0046513 biological_process ceramide biosynthetic process
ENSP00000325485 GO:0005789 cellular_component endoplasmic reticulum membrane
ENSP00000325485 GO:0016021 cellular_component integral component of membrane
ENSP00000325485 GO:0031965 cellular_component nuclear membrane
ENSP00000325485 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSP00000325485 GO:0043565 molecular_function sequence-specific DNA binding
ENSP00000325485 GO:0050291 molecular_function sphingosine N-acyltransferase activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7029 Acyrthosiphon pisum 100164476 10224 Saccoglossus kowalevskii 100373352
9483 Callithrix jacchus 100400191 10029 Cricetulus griseus 100761613
9597 Pan paniscus 100980816 9555 Papio anubis 101007470
39432 Saimiri boliviensis 101031310 6087 Hydra magnipapillata 101237792
43179 Ictidomys tridecemlineatus 101956450 7897 Latimeria chalumnae 102345762
10090 Mus musculus 241447 7227 Drosophila melanogaster 50392
9913 Bos taurus 505233 7668 Strongylocentrotus purpuratus 582683
7070 Tribolium castaneum 656449 9544 Macaca mulatta 713449
13616 Monodelphis domestica 100024030 8083 Xiphophorus maculatus 102231596
9615 Canis familiaris ENSCAFG00000008262 51511 Ciona savignyi ENSCSAVG00000009299
61853 Nomascus leucogenys ENSNLEG00000017804 9978 Ochotona princeps ENSOPRG00000003483
99883 Tetraodon nigroviridis ENSTNIG00000018265 9739 Tursiops truncatus ENSTTRG00000001014
28377 Anolis carolinensis ENSACAG00000017080 9646 Ailuropoda melanoleuca ENSAMEG00000001228
9358 Choloepus hoffmanni ENSCHOG00000005043 7719 Ciona intestinalis ENSCING00000011786
10141 Cavia porcellus ENSCPOG00000000418 7955 Danio rerio ENSDARG00000002365
10020 Dipodomys ordii ENSDORG00000004633 9796 Equus caballus ENSECAG00000007356
9365 Erinaceus europaeus ENSEEUG00000008101 9371 Echinops telfairi ENSETEG00000003248
9685 Felis catus ENSFCAG00000009464 69293 Gasterosteus aculeatus ENSGACG00000005678
9595 Gorilla gorilla ENSGGOG00000009137 8049 Gadus morhua ENSGMOG00000013107
9785 Loxodonta africana ENSLAFG00000000642 30608 Microcebus murinus ENSMICG00000015675
59463 Myotis lucifugus ENSMLUG00000005134 9669 Mustela putorius furo ENSMPUG00000014284
9258 Ornithorhynchus anatinus ENSOANG00000008493 9986 Oryctolagus cuniculus ENSOCUG00000012843
30611 Otolemur garnettii ENSOGAG00000004668 8128 Oreochromis niloticus ENSONIG00000006868
8090 Oryzias latipes ENSORLG00000006833 9813 Procavia capensis ENSPCAG00000006092
7757 Petromyzon marinus ENSPMAG00000008314 13735 Pelodiscus sinensis ENSPSIG00000014728
9598 Pan troglodytes ENSPTRG00000004927 132908 Pteropus vampyrus ENSPVAG00000006713
10116 Rattus norvegicus ENSRNOG00000024595 42254 Sorex araneus ENSSARG00000004515
9305 Sarcophilus harrisii ENSSHAG00000006944 37347 Tupaia belangeri ENSTBEG00000005683
59729 Taeniopygia guttata ENSTGUG00000003577 31033 Takifugu rubripes ENSTRUG00000018396
9478 Tarsius syrichta ENSTSYG00000007489 30538 Vicugna pacos ENSVPAG00000004483
8364 Xenopus tropicalis ENSXETG00000013344