Basic Information
Gene ID ENSBTAG00000010111
Gene Name TCF7L1
Full Name Uncharacterized protein
Organism Bos taurus [9913]

Cross Reference
UniProt F1MJS2 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSBTAP00000013336 Gene3D G3DSA:1.10.30.10 IPR009071 197 279 2.80e-27 High mobility group box domain
ENSBTAP00000013336 PANTHER PTHR10373 IPR024940 1 442 0.00e-00 Transcription factor TCF/LEF
ENSBTAP00000013336 PANTHER PTHR10373:SF29 IPR028776 1 442 0.00e-00 Transcription factor 7-like 1, mammalian-type
ENSBTAP00000013336 Pfam PF00505 IPR009071 199 266 2.90e-21 High mobility group box domain
ENSBTAP00000013336 Pfam PF08347 IPR013558 20 103 3.80e-35 CTNNB1 binding, N-teminal
ENSBTAP00000013336 ProSiteProfiles PS50118 IPR009071 199 267 0.00e-00 High mobility group box domain
ENSBTAP00000013336 SMART SM00398 IPR009071 198 268 2.10e-23 High mobility group box domain
ENSBTAP00000013336 SUPERFAMILY SSF47095 IPR009071 198 279 0.00e-00 High mobility group box domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSBTAP00000013336 PF08347 3.8e-35 CTNNB1_binding N-terminal CTNNB1 binding
ENSBTAP00000013336 PF00505 1.5e-21 HMG_box HMG (high mobility group) box
ENSBTAP00000013336 PF09011 1.7e-08 HMG_box_2 HMG-box domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSBTAP00000013336 GO:0006351 biological_process transcription, DNA-templated
ENSBTAP00000013336 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSBTAP00000013336 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
ENSBTAP00000013336 GO:0007275 biological_process multicellular organismal development
ENSBTAP00000013336 GO:0016055 biological_process Wnt signaling pathway
ENSBTAP00000013336 GO:0060070 biological_process canonical Wnt signaling pathway
ENSBTAP00000013336 GO:0005634 cellular_component nucleus
ENSBTAP00000013336 GO:0003677 molecular_function DNA binding
ENSBTAP00000013336 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSBTAP00000013336 GO:0008013 molecular_function beta-catenin binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100120687 8128 Oreochromis niloticus 100698220
39432 Saimiri boliviensis 101033762 7227 Drosophila melanogaster 43769
9544 Macaca mulatta 694560 9646 Ailuropoda melanoleuca ENSAMEG00000002051
6087 Hydra magnipapillata 100199257 400682 Amphimedon queenslandica 100641322
8090 Oryzias latipes 100820729 34638 Metaseiulus occidentalis 100905988
9597 Pan paniscus 100968002 9555 Papio anubis 101017547
6239 Caenorhabditis elegans 171849 10090 Mus musculus 21415
7955 Danio rerio 30523 7070 Tribolium castaneum 641465
9615 Canis familiaris ENSCAFG00000007832 9358 Choloepus hoffmanni ENSCHOG00000003739
10141 Cavia porcellus ENSCPOG00000014492 10020 Dipodomys ordii ENSDORG00000013753
9796 Equus caballus ENSECAG00000022931 9371 Echinops telfairi ENSETEG00000018020
9595 Gorilla gorilla ENSGGOG00000008549 7897 Latimeria chalumnae ENSLACG00000002104
9785 Loxodonta africana ENSLAFG00000016275 59463 Myotis lucifugus ENSMLUG00000003918
9669 Mustela putorius furo ENSMPUG00000008657 61853 Nomascus leucogenys ENSNLEG00000001462
9986 Oryctolagus cuniculus ENSOCUG00000008749 30611 Otolemur garnettii ENSOGAG00000001078
9978 Ochotona princeps ENSOPRG00000014672 9813 Procavia capensis ENSPCAG00000011792
9601 Pongo abelii ENSPPYG00000012234 9598 Pan troglodytes ENSPTRG00000012128
132908 Pteropus vampyrus ENSPVAG00000002649 9823 Sus scrofa ENSSSCG00000008241
99883 Tetraodon nigroviridis ENSTNIG00000006080 31033 Takifugu rubripes ENSTRUG00000001134
9478 Tarsius syrichta ENSTSYG00000002447 9739 Tursiops truncatus ENSTTRG00000008959
7719 Ciona intestinalis ENSCING00000002003 9483 Callithrix jacchus ENSCJAG00000011025
9365 Erinaceus europaeus ENSEEUG00000003751 9685 Felis catus ENSFCAG00000003376
69293 Gasterosteus aculeatus ENSGACG00000011184 9031 Gallus gallus ENSGALG00000026476
8049 Gadus morhua ENSGMOG00000018031 9315 Macropus eugenii ENSMEUG00000014957
13616 Monodelphis domestica ENSMODG00000015573 9305 Sarcophilus harrisii ENSSHAG00000006659
43179 Ictidomys tridecemlineatus ENSSTOG00000021988 8083 Xiphophorus maculatus ENSXMAG00000001901

Paralogs
ENSBTAG00000021574