Basic Information
Gene ID ENSCAFG00000017707
Gene Name NULL
Full Name Signal transducer and activator of transcription
Organism Canis familiaris [9615]

Cross Reference
UniProt J9P7J4 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSCAFP00000041631 Gene3D G3DSA:1.10.238.10 IPR011992 438 558 2.50e-41 EF-hand domain pair
ENSCAFP00000041631 Gene3D G3DSA:1.10.532.10 IPR013799 1 122 3.10e-28 STAT transcription factor, protein interaction
ENSCAFP00000041631 Gene3D G3DSA:1.20.1050.20 IPR013800 136 305 5.30e-38 STAT transcription factor, all-alpha
ENSCAFP00000041631 Gene3D G3DSA:2.60.40.630 IPR012345 306 437 1.20e-34 STAT transcription factor, DNA-binding, subdomain
ENSCAFP00000041631 Gene3D G3DSA:3.30.505.10 IPR000980 560 678 4.00e-38 SH2 domain
ENSCAFP00000041631 PANTHER PTHR11801 IPR001217 2 750 0.00e-00 Transcription factor STAT
ENSCAFP00000041631 Pfam PF00017 IPR000980 556 608 2.90e-08 SH2 domain
ENSCAFP00000041631 Pfam PF01017 IPR013800 136 302 6.90e-37 STAT transcription factor, all-alpha
ENSCAFP00000041631 Pfam PF02864 IPR013801 305 544 2.40e-81 STAT transcription factor, DNA-binding
ENSCAFP00000041631 Pfam PF02865 IPR013799 2 122 3.10e-31 STAT transcription factor, protein interaction
ENSCAFP00000041631 Pfam PF12188 IPR022756 758 813 2.70e-31 Signal transducer and activation of transcription 2, C-terminal
ENSCAFP00000041631 ProSiteProfiles PS50001 IPR000980 550 685 0.00e-00 SH2 domain
ENSCAFP00000041631 SMART SM00252 IPR000980 548 629 2.90e-04 SH2 domain
ENSCAFP00000041631 SMART SM00964 IPR013799 2 123 3.20e-56 STAT transcription factor, protein interaction
ENSCAFP00000041631 SUPERFAMILY SSF47655 IPR015988 136 305 0.00e-00 STAT transcription factor, coiled coil
ENSCAFP00000041631 SUPERFAMILY SSF48092 IPR013799 1 122 0.00e-00 STAT transcription factor, protein interaction
ENSCAFP00000041631 SUPERFAMILY SSF49417 IPR008967 306 545 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSCAFP00000041631 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSCAFP00000041631 PF01017 2.9e-37 STAT_alpha STAT protein, all-alpha domain
ENSCAFP00000041631 PF12188 2.7e-31 STAT2_C Signal transducer and activator of transcription 2 C terminal
ENSCAFP00000041631 PF02865 3.1e-31 STAT_int STAT protein, protein interaction domain
ENSCAFP00000041631 PF00017 1.2e-08 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSCAFP00000041631 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
ENSCAFP00000041631 GO:0007259 biological_process JAK-STAT cascade
ENSCAFP00000041631 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSCAFP00000041631 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSCAFP00000041631 GO:0005634 cellular_component nucleus
ENSCAFP00000041631 GO:0005737 cellular_component cytoplasm
ENSCAFP00000041631 GO:0003677 molecular_function DNA binding
ENSCAFP00000041631 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSCAFP00000041631 GO:0004871 molecular_function signal transducer activity
ENSCAFP00000041631 GO:0005509 molecular_function calcium ion binding

Paralogs
ENSCAFG00000000121