Basic Information
Gene ID ENSECAG00000020875
Gene Name RUNX2
Full Name Runt-related transcription factor 2
Organism Equus caballus [9796]

Cross Reference
UniProt F6TIE9 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSECAP00000018481 Gene3D G3DSA:2.60.40.720 IPR012346 73 198 4.10e-75 p53/RUNT-type transcription factor, DNA-binding domain
ENSECAP00000018481 Gene3D G3DSA:4.10.770.10 IPR027384 301 358 1.60e-23 Runx, central domain
ENSECAP00000018481 PANTHER PTHR11950 IPR000040 1 462 0.00e-00 Acute myeloid leukemia 1 protein (AML1)/Runt
ENSECAP00000018481 Pfam PF00853 IPR013524 74 196 1.20e-73 Runt domain
ENSECAP00000018481 Pfam PF08504 IPR013711 368 462 9.50e-44 Runx, C-terminal domain
ENSECAP00000018481 PIRSF PIRSF009374 IPR016554 1 462 1.60e-249 Runt-related transcription factor RUNX
ENSECAP00000018481 PRINTS PR00967 IPR000040 104 123 7.80e-111 Acute myeloid leukemia 1 protein (AML1)/Runt
ENSECAP00000018481 PRINTS PR00967 IPR000040 124 145 7.80e-111 Acute myeloid leukemia 1 protein (AML1)/Runt
ENSECAP00000018481 PRINTS PR00967 IPR000040 146 167 7.80e-111 Acute myeloid leukemia 1 protein (AML1)/Runt
ENSECAP00000018481 PRINTS PR00967 IPR000040 168 190 7.80e-111 Acute myeloid leukemia 1 protein (AML1)/Runt
ENSECAP00000018481 PRINTS PR00967 IPR000040 360 379 7.80e-111 Acute myeloid leukemia 1 protein (AML1)/Runt
ENSECAP00000018481 PRINTS PR00967 IPR000040 386 400 7.80e-111 Acute myeloid leukemia 1 protein (AML1)/Runt
ENSECAP00000018481 PRINTS PR00967 IPR000040 402 416 7.80e-111 Acute myeloid leukemia 1 protein (AML1)/Runt
ENSECAP00000018481 PRINTS PR00967 IPR000040 431 448 7.80e-111 Acute myeloid leukemia 1 protein (AML1)/Runt
ENSECAP00000018481 PRINTS PR00967 IPR000040 82 103 7.80e-111 Acute myeloid leukemia 1 protein (AML1)/Runt
ENSECAP00000018481 ProSiteProfiles PS51062 IPR013524 65 192 0.00e-00 Runt domain
ENSECAP00000018481 SUPERFAMILY SSF49417 IPR008967 73 192 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSECAP00000018481 PF00853 0 Runt Runt domain
ENSECAP00000018481 PF08504 9.52883e-44 RunxI Runx inhibition domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSECAP00000018481 GO:0005634 cellular_component nucleus
ENSECAP00000018481 GO:0005524 molecular_function ATP binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9555 Papio anubis 101005700 9595 Gorilla gorilla 101147953
10116 Rattus norvegicus 367218 7668 Strongylocentrotus purpuratus 373468
28377 Anolis carolinensis ENSACAG00000013003 9358 Choloepus hoffmanni ENSCHOG00000005639
9361 Dasypus novemcinctus ENSDNOG00000015041 13616 Monodelphis domestica 100619969
9597 Pan paniscus 100970671 39432 Saimiri boliviensis 101034272
10090 Mus musculus 12393 9598 Pan troglodytes 472017
9646 Ailuropoda melanoleuca ENSAMEG00000009223 9913 Bos taurus ENSBTAG00000004104
9483 Callithrix jacchus ENSCJAG00000012153 10141 Cavia porcellus ENSCPOG00000005277
7955 Danio rerio ENSDARG00000059233 10020 Dipodomys ordii ENSDORG00000007645
9365 Erinaceus europaeus ENSEEUG00000009243 9371 Echinops telfairi ENSETEG00000004708
9031 Gallus gallus ENSGALG00000026484 8049 Gadus morhua ENSGMOG00000010468
30608 Microcebus murinus ENSMICG00000012251 59463 Myotis lucifugus ENSMLUG00000000514
61853 Nomascus leucogenys ENSNLEG00000003611 9258 Ornithorhynchus anatinus ENSOANG00000008265
9986 Oryctolagus cuniculus ENSOCUG00000011739 8128 Oreochromis niloticus ENSONIG00000008210
9978 Ochotona princeps ENSOPRG00000002943 8090 Oryzias latipes ENSORLG00000010169
9813 Procavia capensis ENSPCAG00000005288 7757 Petromyzon marinus ENSPMAG00000000391
9601 Pongo abelii ENSPPYG00000016664 42254 Sorex araneus ENSSARG00000001376
9823 Sus scrofa ENSSSCG00000025551 43179 Ictidomys tridecemlineatus ENSSTOG00000010163
59729 Taeniopygia guttata ENSTGUG00000013249 99883 Tetraodon nigroviridis ENSTNIG00000009685
9478 Tarsius syrichta ENSTSYG00000008524 9739 Tursiops truncatus ENSTTRG00000006943
30538 Vicugna pacos ENSVPAG00000003613 8083 Xiphophorus maculatus ENSXMAG00000003400
9685 Felis catus ENSFCAG00000022480 69293 Gasterosteus aculeatus ENSGACG00000012322
7897 Latimeria chalumnae ENSLACG00000011545 9785 Loxodonta africana ENSLAFG00000005054
9103 Meleagris gallopavo ENSMGAG00000014267 9669 Mustela putorius furo ENSMPUG00000012508
30611 Otolemur garnettii ENSOGAG00000003900 13735 Pelodiscus sinensis ENSPSIG00000014293
132908 Pteropus vampyrus ENSPVAG00000001720 9305 Sarcophilus harrisii ENSSHAG00000009950
37347 Tupaia belangeri ENSTBEG00000000948 31033 Takifugu rubripes ENSTRUG00000003501
8364 Xenopus tropicalis ENSXETG00000001397