Basic Information
Gene ID ENSFCAG00000028112
Gene Name STAT5B
Full Name Signal transducer and activator of transcription
Organism Felis catus [9685]

Cross Reference
UniProt M3X4V6 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSFCAP00000021657 Gene3D G3DSA:1.10.238.10 IPR011992 474 599 1.10e-47 EF-hand domain pair
ENSFCAP00000021657 Gene3D G3DSA:1.10.532.10 IPR013799 2 126 5.50e-48 STAT transcription factor, protein interaction
ENSFCAP00000021657 Gene3D G3DSA:1.20.1050.20 IPR013800 140 186 2.20e-10 STAT transcription factor, all-alpha
ENSFCAP00000021657 Gene3D G3DSA:2.60.40.630 IPR012345 335 473 5.90e-69 STAT transcription factor, DNA-binding, subdomain
ENSFCAP00000021657 Gene3D G3DSA:3.30.505.10 IPR000980 600 714 6.80e-41 SH2 domain
ENSFCAP00000021657 PANTHER PTHR11801 IPR001217 3 781 0.00e-00 Transcription factor STAT
ENSFCAP00000021657 Pfam PF00017 IPR000980 597 669 1.80e-10 SH2 domain
ENSFCAP00000021657 Pfam PF01017 IPR013800 139 186 1.30e-07 STAT transcription factor, all-alpha
ENSFCAP00000021657 Pfam PF02864 IPR013801 334 585 1.60e-99 STAT transcription factor, DNA-binding
ENSFCAP00000021657 Pfam PF02865 IPR013799 3 126 4.60e-47 STAT transcription factor, protein interaction
ENSFCAP00000021657 ProSiteProfiles PS50001 IPR000980 591 688 0.00e-00 SH2 domain
ENSFCAP00000021657 SMART SM00252 IPR000980 589 707 5.80e-08 SH2 domain
ENSFCAP00000021657 SMART SM00964 IPR013799 3 127 3.10e-65 STAT transcription factor, protein interaction
ENSFCAP00000021657 SUPERFAMILY SSF47655 IPR015988 138 186 0.00e-00 STAT transcription factor, coiled coil
ENSFCAP00000021657 SUPERFAMILY SSF48092 IPR013799 2 125 0.00e-00 STAT transcription factor, protein interaction
ENSFCAP00000021657 SUPERFAMILY SSF49417 IPR008967 331 586 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSFCAP00000021657 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSFCAP00000021657 PF02865 0 STAT_int STAT protein, protein interaction domain
ENSFCAP00000021657 PF00017 1.4e-11 SH2 SH2 domain
ENSFCAP00000021657 PF01017 5e-08 STAT_alpha STAT protein, all-alpha domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSFCAP00000021657 GO:0001553 biological_process luteinization
ENSFCAP00000021657 GO:0001779 biological_process natural killer cell differentiation
ENSFCAP00000021657 GO:0006351 biological_process transcription, DNA-templated
ENSFCAP00000021657 GO:0007259 biological_process JAK-STAT cascade
ENSFCAP00000021657 GO:0007565 biological_process female pregnancy
ENSFCAP00000021657 GO:0007595 biological_process lactation
ENSFCAP00000021657 GO:0019218 biological_process regulation of steroid metabolic process
ENSFCAP00000021657 GO:0019915 biological_process lipid storage
ENSFCAP00000021657 GO:0030155 biological_process regulation of cell adhesion
ENSFCAP00000021657 GO:0030856 biological_process regulation of epithelial cell differentiation
ENSFCAP00000021657 GO:0038161 biological_process prolactin signaling pathway
ENSFCAP00000021657 GO:0040018 biological_process positive regulation of multicellular organism growth
ENSFCAP00000021657 GO:0042104 biological_process positive regulation of activated T cell proliferation
ENSFCAP00000021657 GO:0043029 biological_process T cell homeostasis
ENSFCAP00000021657 GO:0043066 biological_process negative regulation of apoptotic process
ENSFCAP00000021657 GO:0045086 biological_process positive regulation of interleukin-2 biosynthetic process
ENSFCAP00000021657 GO:0045579 biological_process positive regulation of B cell differentiation
ENSFCAP00000021657 GO:0045647 biological_process negative regulation of erythrocyte differentiation
ENSFCAP00000021657 GO:0045931 biological_process positive regulation of mitotic cell cycle
ENSFCAP00000021657 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSFCAP00000021657 GO:0046543 biological_process development of secondary female sexual characteristics
ENSFCAP00000021657 GO:0050729 biological_process positive regulation of inflammatory response
ENSFCAP00000021657 GO:0005634 cellular_component nucleus
ENSFCAP00000021657 GO:0005737 cellular_component cytoplasm
ENSFCAP00000021657 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSFCAP00000021657 GO:0004871 molecular_function signal transducer activity
ENSFCAP00000021657 GO:0005509 molecular_function calcium ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9986 Oryctolagus cuniculus 100348267 9601 Pongo abelii 100462537
400682 Amphimedon queenslandica 100641588 9597 Pan paniscus 100989105
9555 Papio anubis 101000002 39432 Saimiri boliviensis 101043203
10090 Mus musculus 20851 10116 Rattus norvegicus 25126
9031 Gallus gallus 395556 9823 Sus scrofa 397340
7227 Drosophila melanogaster 42428 7668 Strongylocentrotus purpuratus 576433
9646 Ailuropoda melanoleuca ENSAMEG00000006061 9615 Canis familiaris ENSCAFG00000015509
9358 Choloepus hoffmanni ENSCHOG00000005387 10141 Cavia porcellus ENSCPOG00000026466
9361 Dasypus novemcinctus ENSDNOG00000007398 9796 Equus caballus ENSECAG00000007847
9371 Echinops telfairi ENSETEG00000008528 9595 Gorilla gorilla ENSGGOG00000008216
9103 Meleagris gallopavo ENSMGAG00000003430 30608 Microcebus murinus ENSMICG00000011988
59463 Myotis lucifugus ENSMLUG00000012050 61853 Nomascus leucogenys ENSNLEG00000011444
9258 Ornithorhynchus anatinus ENSOANG00000006496 9978 Ochotona princeps ENSOPRG00000008312
8090 Oryzias latipes ENSORLG00000003961 13735 Pelodiscus sinensis ENSPSIG00000015138
9598 Pan troglodytes ENSPTRG00000009198 132908 Pteropus vampyrus ENSPVAG00000003876
42254 Sorex araneus ENSSARG00000014205 43179 Ictidomys tridecemlineatus ENSSTOG00000006691
37347 Tupaia belangeri ENSTBEG00000009608 59729 Taeniopygia guttata ENSTGUG00000002572
9739 Tursiops truncatus ENSTTRG00000006684 30538 Vicugna pacos ENSVPAG00000005450

Paralogs
ENSFCAG00000002153