Basic Information
Gene ID ENSGALG00000005757
Gene Name IRF8
Full Name Interferon regulatory factor 8
Organism Gallus gallus [9031]

Cross Reference
UniProt R9PXM4 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSGALP00000009229 Gene3D G3DSA:1.10.10.10 IPR011991 9 120 3.10e-50 Winged helix-turn-helix DNA-binding domain
ENSGALP00000009229 Gene3D G3DSA:2.60.200.10 IPR017855 194 418 1.90e-72 SMAD domain-like
ENSGALP00000009229 Pfam PF00605 IPR001346 9 114 4.50e-47 Interferon regulatory factor DNA-binding domain
ENSGALP00000009229 Pfam PF10401 IPR019471 205 382 1.60e-60 Interferon regulatory factor-3
ENSGALP00000009229 PRINTS PR00267 IPR001346 35 48 7.20e-30 Interferon regulatory factor DNA-binding domain
ENSGALP00000009229 PRINTS PR00267 IPR001346 53 70 7.20e-30 Interferon regulatory factor DNA-binding domain
ENSGALP00000009229 PRINTS PR00267 IPR001346 75 97 7.20e-30 Interferon regulatory factor DNA-binding domain
ENSGALP00000009229 PRINTS PR00267 IPR001346 9 28 7.20e-30 Interferon regulatory factor DNA-binding domain
ENSGALP00000009229 ProSitePatterns PS00601 IPR019817 28 61 - Interferon regulatory factor, conserved site
ENSGALP00000009229 ProSiteProfiles PS51507 IPR001346 7 114 0.00e-00 Interferon regulatory factor DNA-binding domain
ENSGALP00000009229 SMART SM00348 IPR001346 3 115 5.40e-68 Interferon regulatory factor DNA-binding domain
ENSGALP00000009229 SUPERFAMILY SSF49879 IPR008984 206 416 0.00e-00 SMAD/FHA domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSGALP00000009229 PF00605 0 IRF Interferon regulatory factor transcription factor
ENSGALP00000009229 PF10401 0 IRF-3 Interferon-regulatory factor 3

Gene Ontology Annotation
Protein Entry Name Space Description
ENSGALP00000009229 GO:0005634 cellular_component nucleus
ENSGALP00000009229 GO:0000975 molecular_function regulatory region DNA binding
ENSGALP00000009229 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9986 Oryctolagus cuniculus 100350620 61853 Nomascus leucogenys 100598495
8128 Oreochromis niloticus 100702346 10029 Cricetulus griseus 100770390
9597 Pan paniscus 100969190 9555 Papio anubis 101020216
39432 Saimiri boliviensis 101040525 9595 Gorilla gorilla 101152979
9669 Mustela putorius furo 101679661 43179 Ictidomys tridecemlineatus 101971354
8083 Xiphophorus maculatus 102220694 13735 Pelodiscus sinensis 102455775
9606 Homo sapiens 10379 10090 Mus musculus 15900
7955 Danio rerio 403013 9615 Canis familiaris 489673
9913 Bos taurus 614909 9544 Macaca mulatta 693933
28377 Anolis carolinensis ENSACAG00000005409 9646 Ailuropoda melanoleuca ENSAMEG00000018268
10141 Cavia porcellus ENSCPOG00000027266 51511 Ciona savignyi ENSCSAVG00000008812
10020 Dipodomys ordii ENSDORG00000015963 9796 Equus caballus ENSECAG00000015449
9365 Erinaceus europaeus ENSEEUG00000002644 9371 Echinops telfairi ENSETEG00000008368
9685 Felis catus ENSFCAG00000007615 69293 Gasterosteus aculeatus ENSGACG00000015958
8049 Gadus morhua ENSGMOG00000003945 7897 Latimeria chalumnae ENSLACG00000005859
30608 Microcebus murinus ENSMICG00000012090 59463 Myotis lucifugus ENSMLUG00000005109
13616 Monodelphis domestica ENSMODG00000004572 9978 Ochotona princeps ENSOPRG00000002139
8090 Oryzias latipes ENSORLG00000018216 9813 Procavia capensis ENSPCAG00000004460
9601 Pongo abelii ENSPPYG00000007620 9598 Pan troglodytes ENSPTRG00000008435
132908 Pteropus vampyrus ENSPVAG00000003758 9823 Sus scrofa ENSSSCG00000023184
37347 Tupaia belangeri ENSTBEG00000013828 59729 Taeniopygia guttata ENSTGUG00000004127
99883 Tetraodon nigroviridis ENSTNIG00000009283 31033 Takifugu rubripes ENSTRUG00000018213
9478 Tarsius syrichta ENSTSYG00000007445 9739 Tursiops truncatus ENSTTRG00000016024
30538 Vicugna pacos ENSVPAG00000006643 8364 Xenopus tropicalis ENSXETG00000003561