Basic Information
Gene ID ENSGALG00000026718
Gene Name HIC1
Full Name Hypermethylated in cancer 1 protein
Organism Gallus gallus [9031]

Cross Reference
UniProt R4GFN9 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSGALP00000040837 Gene3D G3DSA:3.30.160.60 IPR013087 445 475 7.40e-07 Zinc finger C2H2-type/integrase DNA-binding domain
ENSGALP00000040837 Gene3D G3DSA:3.30.160.60 IPR013087 476 499 9.70e-13 Zinc finger C2H2-type/integrase DNA-binding domain
ENSGALP00000040837 Gene3D G3DSA:3.30.160.60 IPR013087 500 522 4.60e-14 Zinc finger C2H2-type/integrase DNA-binding domain
ENSGALP00000040837 Gene3D G3DSA:3.30.160.60 IPR013087 523 553 8.30e-15 Zinc finger C2H2-type/integrase DNA-binding domain
ENSGALP00000040837 Gene3D G3DSA:3.30.710.10 IPR011333 13 129 4.20e-28 BTB/POZ fold
ENSGALP00000040837 PANTHER PTHR11389:SF322 IPR028424 1 556 0.00e-00 Hypermethylated in cancer 1 protein
ENSGALP00000040837 Pfam PF00096 IPR007087 447 469 2.10e-04 Zinc finger, C2H2
ENSGALP00000040837 Pfam PF00096 IPR007087 475 497 1.50e-05 Zinc finger, C2H2
ENSGALP00000040837 Pfam PF00651 IPR013069 26 132 3.50e-24 BTB/POZ
ENSGALP00000040837 ProSitePatterns PS00028 IPR007087 395 415 - Zinc finger, C2H2
ENSGALP00000040837 ProSitePatterns PS00028 IPR007087 449 469 - Zinc finger, C2H2
ENSGALP00000040837 ProSitePatterns PS00028 IPR007087 477 497 - Zinc finger, C2H2
ENSGALP00000040837 ProSitePatterns PS00028 IPR007087 505 525 - Zinc finger, C2H2
ENSGALP00000040837 ProSitePatterns PS00028 IPR007087 533 553 - Zinc finger, C2H2
ENSGALP00000040837 ProSiteProfiles PS50097 IPR000210 36 99 0.00e-00 BTB/POZ-like
ENSGALP00000040837 ProSiteProfiles PS50157 IPR007087 393 420 0.00e-00 Zinc finger, C2H2
ENSGALP00000040837 ProSiteProfiles PS50157 IPR007087 447 474 0.00e-00 Zinc finger, C2H2
ENSGALP00000040837 ProSiteProfiles PS50157 IPR007087 475 502 0.00e-00 Zinc finger, C2H2
ENSGALP00000040837 ProSiteProfiles PS50157 IPR007087 503 530 0.00e-00 Zinc finger, C2H2
ENSGALP00000040837 ProSiteProfiles PS50157 IPR007087 531 558 0.00e-00 Zinc finger, C2H2
ENSGALP00000040837 SMART SM00225 IPR000210 36 133 8.80e-27 BTB/POZ-like
ENSGALP00000040837 SMART SM00355 IPR015880 393 415 3.50e-04 Zinc finger, C2H2-like
ENSGALP00000040837 SMART SM00355 IPR015880 447 469 7.70e-06 Zinc finger, C2H2-like
ENSGALP00000040837 SMART SM00355 IPR015880 475 497 3.00e-08 Zinc finger, C2H2-like
ENSGALP00000040837 SMART SM00355 IPR015880 503 525 1.50e-06 Zinc finger, C2H2-like
ENSGALP00000040837 SMART SM00355 IPR015880 531 553 1.70e-06 Zinc finger, C2H2-like
ENSGALP00000040837 SUPERFAMILY SSF54695 IPR011333 13 131 0.00e-00 BTB/POZ fold

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSGALP00000040837 PF00651 2e-24 BTB BTB/POZ domain
ENSGALP00000040837 PF00096 2.3e-24 zf-C2H2 Zinc finger, C2H2 type
ENSGALP00000040837 PF13465 2.3e-21 zf-H2C2_2 Zinc-finger double domain
ENSGALP00000040837 PF13894 3e-20 zf-C2H2_4 C2H2-type zinc finger
ENSGALP00000040837 PF12171 9.9e-18 zf-C2H2_jaz Zinc-finger double-stranded RNA-binding
ENSGALP00000040837 PF12874 5.3e-11 zf-met Zinc-finger of C2H2 type
ENSGALP00000040837 PF13912 7.6e-10 zf-C2H2_6 C2H2-type zinc finger
ENSGALP00000040837 PF12756 3.3e-05 zf-C2H2_2 C2H2 type zinc-finger (2 copies)

Gene Ontology Annotation
Protein Entry Name Space Description
ENSGALP00000040837 GO:0006351 biological_process transcription, DNA-templated
ENSGALP00000040837 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSGALP00000040837 GO:0005634 cellular_component nucleus
ENSGALP00000040837 GO:0003677 molecular_function DNA binding
ENSGALP00000040837 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9823 Sus scrofa 100525779 8128 Oreochromis niloticus 100694398
30611 Otolemur garnettii 100954137 9597 Pan paniscus 100994626
9669 Mustela putorius furo 101674299 7897 Latimeria chalumnae 102359906
9606 Homo sapiens 3090 9646 Ailuropoda melanoleuca ENSAMEG00000007657
9913 Bos taurus ENSBTAG00000025130 10141 Cavia porcellus ENSCPOG00000020382
10020 Dipodomys ordii ENSDORG00000016613 9796 Equus caballus ENSECAG00000004462
69293 Gasterosteus aculeatus ENSGACG00000010848 9595 Gorilla gorilla ENSGGOG00000027584
9785 Loxodonta africana ENSLAFG00000001259 9103 Meleagris gallopavo ENSMGAG00000005397
30608 Microcebus murinus ENSMICG00000012908 9544 Macaca mulatta ENSMMUG00000030393
13616 Monodelphis domestica ENSMODG00000010600 10090 Mus musculus ENSMUSG00000043099
8090 Oryzias latipes ENSORLG00000004895 9601 Pongo abelii ENSPPYG00000007789
13735 Pelodiscus sinensis ENSPSIG00000007902 9598 Pan troglodytes ENSPTRG00000008543
132908 Pteropus vampyrus ENSPVAG00000002158 10116 Rattus norvegicus ENSRNOG00000003096
42254 Sorex araneus ENSSARG00000010162 43179 Ictidomys tridecemlineatus ENSSTOG00000011792
59729 Taeniopygia guttata ENSTGUG00000005835 31033 Takifugu rubripes ENSTRUG00000004590
8083 Xiphophorus maculatus ENSXMAG00000001419