Basic Information
Gene ID ENSOGAG00000017198
Gene Name STAT5B
Full Name Signal transducer and activator of transcription
Organism Otolemur garnettii [30611]

Cross Reference
UniProt H0XH20 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSOGAP00000015405 Gene3D G3DSA:1.10.238.10 IPR011992 492 599 6.40e-38 EF-hand domain pair
ENSOGAP00000015405 Gene3D G3DSA:1.10.532.10 IPR013799 1 99 8.30e-35 STAT transcription factor, protein interaction
ENSOGAP00000015405 Gene3D G3DSA:1.20.1050.20 IPR013800 142 335 5.10e-65 STAT transcription factor, all-alpha
ENSOGAP00000015405 Gene3D G3DSA:2.60.40.630 IPR012345 336 470 2.20e-61 STAT transcription factor, DNA-binding, subdomain
ENSOGAP00000015405 Gene3D G3DSA:3.30.505.10 IPR000980 600 714 1.40e-40 SH2 domain
ENSOGAP00000015405 PANTHER PTHR11801 IPR001217 2 780 0.00e-00 Transcription factor STAT
ENSOGAP00000015405 Pfam PF00017 IPR000980 597 669 1.80e-10 SH2 domain
ENSOGAP00000015405 Pfam PF01017 IPR013800 141 333 2.70e-55 STAT transcription factor, all-alpha
ENSOGAP00000015405 Pfam PF02864 IPR013801 335 585 8.80e-78 STAT transcription factor, DNA-binding
ENSOGAP00000015405 Pfam PF02865 IPR013799 2 104 4.30e-35 STAT transcription factor, protein interaction
ENSOGAP00000015405 ProSiteProfiles PS50001 IPR000980 591 688 0.00e-00 SH2 domain
ENSOGAP00000015405 SMART SM00252 IPR000980 589 707 1.70e-08 SH2 domain
ENSOGAP00000015405 SMART SM00964 IPR013799 2 115 5.30e-41 STAT transcription factor, protein interaction
ENSOGAP00000015405 SUPERFAMILY SSF47655 IPR015988 139 335 0.00e-00 STAT transcription factor, coiled coil
ENSOGAP00000015405 SUPERFAMILY SSF48092 IPR013799 1 99 0.00e-00 STAT transcription factor, protein interaction
ENSOGAP00000015405 SUPERFAMILY SSF49417 IPR008967 330 586 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSOGAP00000015405 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSOGAP00000015405 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSOGAP00000015405 PF02865 4.3e-35 STAT_int STAT protein, protein interaction domain
ENSOGAP00000015405 PF00017 1.5e-11 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSOGAP00000015405 GO:0001553 biological_process luteinization
ENSOGAP00000015405 GO:0001779 biological_process natural killer cell differentiation
ENSOGAP00000015405 GO:0006351 biological_process transcription, DNA-templated
ENSOGAP00000015405 GO:0007259 biological_process JAK-STAT cascade
ENSOGAP00000015405 GO:0007565 biological_process female pregnancy
ENSOGAP00000015405 GO:0007595 biological_process lactation
ENSOGAP00000015405 GO:0019218 biological_process regulation of steroid metabolic process
ENSOGAP00000015405 GO:0019915 biological_process lipid storage
ENSOGAP00000015405 GO:0030155 biological_process regulation of cell adhesion
ENSOGAP00000015405 GO:0030856 biological_process regulation of epithelial cell differentiation
ENSOGAP00000015405 GO:0038161 biological_process prolactin signaling pathway
ENSOGAP00000015405 GO:0040018 biological_process positive regulation of multicellular organism growth
ENSOGAP00000015405 GO:0042104 biological_process positive regulation of activated T cell proliferation
ENSOGAP00000015405 GO:0043029 biological_process T cell homeostasis
ENSOGAP00000015405 GO:0043066 biological_process negative regulation of apoptotic process
ENSOGAP00000015405 GO:0045086 biological_process positive regulation of interleukin-2 biosynthetic process
ENSOGAP00000015405 GO:0045579 biological_process positive regulation of B cell differentiation
ENSOGAP00000015405 GO:0045647 biological_process negative regulation of erythrocyte differentiation
ENSOGAP00000015405 GO:0045931 biological_process positive regulation of mitotic cell cycle
ENSOGAP00000015405 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSOGAP00000015405 GO:0046543 biological_process development of secondary female sexual characteristics
ENSOGAP00000015405 GO:0050729 biological_process positive regulation of inflammatory response
ENSOGAP00000015405 GO:0005634 cellular_component nucleus
ENSOGAP00000015405 GO:0005737 cellular_component cytoplasm
ENSOGAP00000015405 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSOGAP00000015405 GO:0004871 molecular_function signal transducer activity
ENSOGAP00000015405 GO:0005509 molecular_function calcium ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
61853 Nomascus leucogenys ENSNLEG00000011444 9978 Ochotona princeps ENSOPRG00000008312
13735 Pelodiscus sinensis ENSPSIG00000015138 37347 Tupaia belangeri ENSTBEG00000009608
42254 Sorex araneus ENSSARG00000014205

Paralogs
100958999